Yasmin Kamal, MD, PhD
@yasminkmdphd
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IM Resident at Brigham & Women’s Hospital | Physician-Scientist | Dartmouth MD PhD | Focus on gastrointestinal cancer genomics and & tumor immunology
Joined October 2021
Do you use logistic regression? If so, you’ll want to read the thread below. ⚠️ Warning: Memes, charts, #rstats, and practical advice ahead.
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Spatial periodicity in grid cell firing is explained by a neural sequence code of 2D trajectories https://t.co/HY3dn2KcjO Thank you to Rebecca R.G. and Giorgio Ascoli for a fantastic collaboration!
biorxiv.org
Spatial periodicity in grid cell firing has been interpreted as a neural metric for space providing animals with a coordinate system in navigating physical and mental spaces. However, the specific...
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🔥Check out our new paper🔥 Make Science Disruptive Again! All graduate programs should teach the CREATIVE SCIENTIFIC PROCESS to help change the research system and increase the disruptiveness of science projects. @MartinJLercher @NatureBiotech
https://t.co/tLXiGQcRId
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In research out today in @Nature, the Rabinowitz Lab's “Slow TCA flux and ATP production in primary solid tumours but not metastases” quantifies for the first time a cancerous tumor’s low energy budget. Great work Josh, @Caroline_Bartma and all: https://t.co/xcEooxBCpc
#cancer
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Out now @ImmunityCP! Our comprehensive #singlecell atlas of >720k intestinal cells from #crohnsdisease patients uncovers transcriptional heterogeneity across tissues/inflammation states & identifies potential regulators of fibrosis. https://t.co/m1qM4R81IB
@MGH_RI
@broadinstitute
cell.com
Crohn’s disease (CD) is a heterogeneous condition impacting the ileum and colon in unique ways. Here, Kong et al. define the unique epithelial, stromal, and immune characteristics of CD by generating...
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📢🥁By popular demand presenting the TOP Oncology publications of 2022. PS: List not exhaustive - so feel free to tag & add important papers to the list @OncoAlert @NEJM @TheLancetOncol @Annals_Oncology @NatureMedicine @Nature @CD_AACR
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Key concept for physician-scientist trainees (and programs) to embrace is that “Real Life” doesn’t wait for us to finish training, nor should it. I am an intern, father, scientist, husband, colleague, friend, neighbor, son… and I am all of these things at the same time.
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Valuable #immunology cell atlas: #scRNAseq + paired B & T cell receptor seq for 330,000 tissue-resident immune cells across 16 human tissues. CellTypist: new & robust immune cells annotation algorithm, finding 101 immune cell types in 1,000,000 cells‼️ Why this is important👇🧵
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Better title for this study might have been: “Colonoscopies prevent cancers and deaths only if people do them” Must recognize that study was more about “invitation for colonoscopy” than “effectiveness” https://t.co/8uehrimR5U
nejm.org
Although colonoscopy is widely used as a screening test to detect colorectal cancer, its effect on the risks of colorectal cancer and related death is unclear. We performed a pragmatic, randomized ...
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Do you want to get into scRNA-seq but are lost in the sea of never-ending papers? No worries, I got you covered. Here's a list of the best review that have help me understand the core concepts of the technique, analysis and interpretation:🧵
@rmassonix do any of you have similar ones for single-cell RNAseq? We want to establish both techniques in my lab!
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Attempts to reinforce a leaky physician-scientist “pipeline" often turn to an institutional narrative. Here, we reflect on the application, interview, and match process as PSTP trainees. @A_P_S_A @DataExplorer21 @BenjaminReisman @jpwaller @yasminkmdphd
https://t.co/wb4MmSenWp
medrxiv.org
Background Replenishing the physician-scientist workforce remains a central mission of medical education, but the hemorrhaging of qualified trainees threatens the physician-scientist role. Among the...
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Paper is finally out in @NatureGenet! "Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment" Check out our catalog of conserved cancer cell states defined by scRNA-Seq & ST. Congrats @BarkleyDalia! https://t.co/MBY3BQSfcM
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Congratulations to Dr. Walter Chan (@WalterChanMD), our Director of the Center for GI Motility & Director of Clinical Research Education, for his #promotion to Associate Professor of Medicine at Harvard Medical School @harvardmed 🍾 #BWHMotility #BrighamGIFaculty #BrighamGIAlum
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1.What if we explored different models for how labs could run? For example? the multi-PI lab. Presently every PI is like a decathlete: paper writing, grant writing, project management, budgeting, mentoring, etc. It would be so fun to run lab w/ other PIs & divide these chores up!
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Anemia might be the most common lab finding I’ve seen in my first month on inpatient servide. Although frequent blood draws are the most common cause, it helps to think broadly:
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