Immunity
@ImmunityCP
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Cutting-edge research in immunology from around the world. This account is no longer monitored, and content is automated. Join us on BlueSky!
Cambridge, MA, USA
Joined May 2011
We are turning this account into a fully automated page. To learn more about what’s going on at Immunity, please follow us on Bluesky! https://t.co/2BFKPbcSGQ
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1/2 Sharing exciting news! ✨ Our recently published paper “Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity” has been selected for the cover of the October issue of Immunity! @ImmunityCP
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Bana Jabri (@BanaJabri, @UChicago) joins the @CellSymposia #CSMicrobiome2026 speaker panel! Explore gut immunity + microbiome disruption. May 10–12 | Bruges Submit abstracts by Jan 16 https://t.co/x1Vnzg2mJK
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Looking forward to #RTN2025 today! Excited for some #neuroimmunology! If you'll be there, please look for me and say hello! @GeneLayInst @RTNconference
https://t.co/MSeW9AUoXw
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Congrats to @alex_lercher, former CeMM PhD student at @bergthalerlab, on receiving one of the @ascina Young Scientist Awards 2025! 👏 The prize honors his 2024 @ImmunityCP paper revealing how the innate immune system can develop antiviral memory. 🔗Paper: https://t.co/5nuRJBWCQb
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Explore the scientific program for @CellSymposia #CSCancerImmunity2025. Join global leaders in cancer immunology to discuss breakthroughs in immune activation, T cell dynamics & immunotherapy. There’s still time to register: https://t.co/RXnYAgagww
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Discover insights into the #immunesystem’s function beyond its traditional remit as the host’s defense system, including its role in maintaining the normal function of organs and tissues @CellSymposia #CSImmuneHomeostasis26 @sjtu1896 Visit:🔗 https://t.co/OaMGz7LyKC
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Online now: Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity
cell.com
The Pfs230:Pfs48/45 complex is the target of leading anti-malaria transmission-blocking vaccine candidates, yet its molecular assembly is poorly understood. Bekkering, Yoo, Hailemariam, et al....
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New publication alert! Eomes drives differentiation of type-1 regulatory CD4 T cells that are critical for limiting immune toxicity and tumor relapse after T cell immunotherapy through dual regulatory and cytotoxic functions. Check it out! @ImmunityCP
https://t.co/GUFimgr5TX
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Could Tr1 CD4+ T cells be the key to decouple anti-tumor effects from the toxicities of immune effector cell therapies?🤔 Proud to have contributed to this work from the @Geoff_Hill_Lab just out in @ImmunityCP! 🥹 https://t.co/qtSh7dR007
@fredhutch
New publication alert! Eomes drives differentiation of type-1 regulatory CD4 T cells that are critical for limiting immune toxicity and tumor relapse after T cell immunotherapy through dual regulatory and cytotoxic functions. Check it out! @ImmunityCP
https://t.co/GUFimgr5TX
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Researchers reveal a mechanism that allows triple negative #BreastCancer (#TNBC) to develop #resistance #to therapy. @XiangZhangLab L. Yu et al @ImmunityCP #BreastCancerAwarenessMonth @bcmhouston
blogs.bcm.edu
The researchers show that disrupting lipid formulation reverses treatment resistance and the immunosuppressive microenvironment.
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Review @ImmunityCP Inflammation in atherosclerosis: Lessons and therapeutic implications https://t.co/Uucstxewx1
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Review @ImmunityCP Obesity, diabetes, and inflammation: Pathophysiology and clinical implications https://t.co/70XvGUBqi5
@DanielJDrucker
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Online now: Inflammation in atherosclerosis: Lessons and therapeutic implications
cell.com
Cardiovascular risk factors can spark inflammation by eliciting misdirected responses of intrinsic vascular cells and leukocytes, culminating in lesion initiation, progression, and complication....
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Online now: Obesity, diabetes, and inflammation: Pathophysiology and clinical implications
cell.com
Obesity and its related disorders are now recognized as chronic inflammatory conditions. Donath and Drucker review the mechanisms underlying inflammation in these settings and discuss how understan...
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#Microbiota #FriendOrFoe? Our own @BostonChildrens Chatila, Benamar &co show @ImmunityCP that #gut microbiota drives Notch3+ Tregs which migrate to brain & interacts with microglia becoming Th17 cells, subvert brain Tregs, supporting multiple sclerosis/EAE https://t.co/DVvs7DC4MH
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Online now: The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells
cell.com
TCF-1, encoded by Tcf7, supports CD8+ T cell memory and is silenced in effector T cells. Murphy et al. identify two cis-elements required for Blimp1-mediated Tcf7 repression and find that decoupling...
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Online now: Notch3 destabilizes regulatory T cells to drive autoimmune neuroinflammation in multiple sclerosis
cell.com
Benamar et al. demonstrate that Notch3+ Treg cells are increased in multiple sclerosis and in EAE. They are induced in the gut by microbiota and translocate to the CNS to degenerate into pathogenic...
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Online now: Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes
cell.com
Type-1 regulatory T cells (Tr1) promote immune tolerance during chronic infection, autoimmunity, and transplantation, but the role of Eomes in Tr1 differentiation and function after cell therapy is...
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Kenya Honda (@Honda1Kenya, @Keio_univPR) presents on immune-microbiota crosstalk at @CellSymposia #CSMicrobiome2026 May 10–12, 2026 | Bruges Abstract deadline: Jan 16 https://t.co/6x62cs629M
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Join us to explore the "middle path" 👇👇👇
Introducing the organizers of #CSImmuneHomeostasis26: 🔹Bing Su (@sjtu1896) 🔹Florent Ginhoux (@GustaveRoussy) 🔹Lai Guan Ng (@Westlake_Uni) 🔹Bruce Koppelman (@ImmunityCP & @CellCellPress) Abstract submission deadline: December 19, 2025 🔗 https://t.co/M6c74Lott0
@CellSymposia
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