Mingqi Han
@MingqiHan
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Assistant Professor/CPRIT Scholar@CSI_MD Anderson Cancer Center Exploring metabolism, organelle communication and quantitative imaging in lung cancer
Houston, TX
Joined April 2019
Excited to share that I'm joining the Cancer Systems Imaging (CSI) @MDAndersonNews as Assistant Professor this July! My lab focus on cancer metabolism and quantitative imaging. We're looking for a highly motivated postdoc to explore "metabolism visualization" across scales!
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Our latest review on #cuproptosis in cancer is now online 👉 Cuproptosis in cancer: from molecular mechanisms to therapeutic intervention https://t.co/Y3c9ItKnzi
@ACKoongMDPhD @BoyiGan @MDAndersonNews
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Happy to see our News & Views is out! We highlight two landmark papers that demonstrate the potential for therapeutic targeting of FSP1 and #ferroptosis in in vivo cancer models. Beautiful work from @ThalesPapaG, Jessalyn Ubellacker, and colleagues. 🥳 https://t.co/RfVaipXVfE
nature.com
Nature Cell Biology - FSP1 is a key suppressor of lipid peroxidation and ferroptosis, yet it is largely dispensable in standard cell culture models. Two new studies now show that FSP1 becomes...
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Congrats to Postdoc Danny Son and all of our colleagues and collaborators on this paper.
Neutrophil-derived IL-1β preserves lipid stores during metabolic stress, highlighting a physiological function of innate immune cells in limiting lipid loss and maintaining energy homeostasis @Nature @UCSDMedSchool @LabSaltiel
https://t.co/5rYZMl75ft
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Organelles share the load | Science
science.org
Peroxisome-mitochondria contact sites manage mitochondrial oxidative stress
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SCI member @LabWinslow & others show aging represses #KRAS driven tumor growth in mouse lung cancer models. Aging dampens tumor suppressor inactivation, especially PTEN, and reduces cancer-aging signatures, revealing tumor-suppressive effects of age. https://t.co/jBHsbMnYVY
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#Throwback REVIEW | @E_MSchneider, @jfcryan Feeding #gut #microbes to nourish the #brain: unravelling the diet–microbiota–gut–brain axis https://t.co/i6rXm53eGa
nature.com
Nature Metabolism - This Review provides an overview of the interplay between host diet and the gut microbiota, and how this affects brain function.
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Super excited to see this study out in Nature from @ThalesPapaG Lab on FSP1's role in protecting against ferroptosis in vivo during tumor progression. Huge congrats to Kat, Thales and the team!🔥 #ferroptosis
https://t.co/GWLrrHeCq5
nature.com
Nature - The ferroptosis suppressor protein FSP1 has a critical role in ferroptosis protection of tumours across multiple in vivo models and is linked to worse prognosis in human lung...
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Our new review article in @NatureRevCancer discussing targeting metabolic cell death (#ferroptosis, #cuproptosis and #disulfidptosis) in cancer https://t.co/x1z6jPzKNJ;
nature.com
Nature Reviews Cancer - In this Review, Mao et al. discuss the regulation and interplay of the metabolic cell death pathways ferroptosis, disulfidptosis and cuproptosis and explore how these...
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Out today the last piece of work that Maria Guillamot did in our lab in a collaboration with @AWeinstock and @DrShrutiNaik (who lead the study) showing type I interferon (IFN)-mediated activation of hematopoietic stem/progenitor cells resulting in profound changes to systemic
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Excited to share our work on discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine biosynthesis. @Cell_Metabolism @RockefellerUniv
cell.com
Khan et al. apply machine learning to identify substrates of UNC93A, SLC45A4, and SLC25A45. Biochemical assays and in vivo metabolite tracing establish SLC25A45 as a key mediator of mitochondrial...
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Spatial Multiomics (Metabolome➡️ Lipidome➡️ Glycome) on a single 10 µm brain section👹 +Sami Spatial Augmented Multiomics Interface with Small Molecule Pathway Database Direct pixel-to-pixel matching across modalities😎 @RCSunlab @NatureComms 2025 https://t.co/66INVGwfar
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Truly a joy to hear @JeffRathmell's keynote at the 14th Metabolism in Cancer Symposium hosted by CSI @MDAndersonNews! Grateful for the positive energy and exciting insights into T cell metabolism & immunotherapy & fever. Look forward to more discoveries from Rathmell Lab!🔬👑
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Great to join @AndreaMiyahira @PCFnews on @urotoday to discuss our @MDAndersonNews research on CAMKK2-CREB signaling + cholesterol metabolism in #prostatecancer. Full interview here➡️
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Highly multiplexed 3D profiling of cell states and immune niches in human tumors @naturemethods @harvardmed 🇺🇸 https://t.co/nJ4EQtJYL5
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Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis
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Preprint from @HaoqiangY & @wantong_yao labs @MDAndersonNews KRAS inhibition activates an actionable CD24 do-not-eat-me signal in #PancreaticCancer
https://t.co/Hg6iFvVodu A new mechanism of resistance to KRAS inhibitors + an autochthonous model of the KRAS G12C allelic variant
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MD Anderson and Nature are bringing together researchers to explore the tumor ecosystem and its impact on cancer development, progression and treatment. Learn more about the free, in-person conference: https://t.co/07LytydJGh
@SpringerNature #EndCancer
mdanderson.org
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🚨 New Review Alert! 🚨 Our latest in CSH Perspectives in Biology explores when, where, and how calcium ions flow between organelles—and why this matters for cellular signaling & health. Read more 👉 #CellBiology #Calcium @cshperspectives
https://t.co/T7DZUWKDPr
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New @CCR_AACR study by Charles Manning @MDAndersonNews Preclinical Fluorescence-Guided Imaging Leveraging Surrounding Sentinel Tumor Microenvironment Identifies High-Risk #PancreaticCancer precursor lesions https://t.co/gvEqFTsGo2
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