Nature Reviews Cancer
@NatureRevCancer
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Nature Reviews Cancer is a monthly review journal for researchers working on cancer. We, the editors, highlight the most exciting topics in cancer research.
London, UK
Joined November 2011
Our DECEMBER issue is live! π
βοΈπ It features articles on: - Cancer therapy-induced peripheral & central neurotoxicity - Ferroptosis potential for cancer therapy - ADCs for cancer therapy - The immune microenvironment of colorectal cancer π π https://t.co/hbZM7SZi9F
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Weekend reading π―οΈπ―οΈ In this #Review, Tang, Wang, Kroemer and Kang outline the regulatory mechanisms of #macropinocytosis, its implications for treatment strategies and potential as a target for enhancing therapeutic efficacy in oncology. πβ¬οΈ https://t.co/arBnDelYod
nature.com
Nature Reviews Cancer - Macropinocytosis enables cancer cells to absorb nutrients from their environment, supporting growth and therapy resistance. In this Review, Tang, Wang, Kroemer and Kang...
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Check out this #ResearchHighlight π A recent study reveals that the endoplasmic reticulum (ER) stress response in leukocytes plays a key role in mediating peripheral nerve damage caused by paclitaxel. @RoyStrowdMD @JCubRuiz πβ¬οΈ https://t.co/mRuMWzsxVO
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NEW content online! The impact of concomitant medications on treatment outcomes in patients with cancer receiving immune checkpoint inhibitors https://t.co/uoByBcwsnC
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You could be here by Friday for a weekend of sun salutations
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NEW content online! A guide to transcriptomic deconvolution in cancer https://t.co/TfoWiA9XRA
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ICYMI π¨ Although ferroptosis is emerging as a therapeutic vulnerability in cancer, clinical translation has faced hurdles. In this #Review, Wahida & Conrad review its biology, immunogenicity & steps towards clinical translation π π https://t.co/RHcsSAMmkV
nature.com
Nature Reviews Cancer - Although ferroptosis, an iron-dependent form of regulated cell death, is emerging as a therapeutic vulnerability in cancer, clinical translation is hindered by...
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ICYMI π¨ Neurotoxicity impacting the central & peripheral nervous systems is an adverse effect of cancer therapies. In this #Review, Karschnia et al. outline the mechanisms that underlie the clinical symptoms & the need for interventions to treat it. π https://t.co/96sUyn6zGf
nature.com
Nature Reviews Cancer - Neurotoxicity impacting the central and peripheral nervous systems is a considerable adverse effect of both conventional and novel cancer therapies. In this Review,...
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ICYMI π¨ In this #Review, Kennel & Greten highlight the role of immune cells in CRC development, progression & metastasis. They emphasize the need for novel strategies to enhance immunogenicity & CRC patient stratification to improve outcomes. π π https://t.co/BEFLCP7uvn
nature.com
Nature Reviews Cancer - In this Review, Kennel and Greten highlight the role of immune cells in colorectal cancer (CRC) development, progression and metastasis as well as the impact of therapies on...
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ICYMI π¨ Inspiring this month's cover, is a review by Zippelius et al., which highlights the molecular interactions and immune system effects of antibody-drug conjugates that drive their efficacy and toxicity. π π https://t.co/6gnoXuWkgD
nature.com
Nature Reviews Cancer - Neurotoxicity impacting the central and peripheral nervous systems is a considerable adverse effect of both conventional and novel cancer therapies. In this Review,...
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#JournalClub π¨ Basurto-Lozada & Robles-Espinoza @UNAM_MX discuss a study that challenges the prevailing view of a monoclonal origin of cancer by showing that early lesions in mouse models of colorectal cancer are polyclonal. πβ¬οΈ https://t.co/DIUyxbfBXt
nature.com
Nature Reviews Cancer - In this Journal Club, Basurto-Lozada and Robles-Espinoza discuss a study that challenges the prevailing view of a monoclonal origin of cancer by showing that early lesions...
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ICYMIπ¨ In light of the #NobelPrize recognizing discoveries in peripheral immune tolerance, our article "Regulatory T cells in the tumour microenvironment" is now free to read. Discover how #Tregs shape cancer immunity π π https://t.co/HjXyNMkYB9
nature.com
Nature Reviews Cancer - This Review by Imianowski et al. outlines the various contributions that regulatory T cells, present in the tumour microenvironment, make towards tumour progression and...
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#Reviewπ¨ Spicer & Co @DoctorJSpicer discuss the role of neutrophil extracellular traps #NETs biology in cancer and emphasize both the translational data available and the need for further clinical trials evaluating NETs & NET-directed therapies. π π https://t.co/68qNLzNina
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NEW content online! One, two, many: how many cells start a tumour?
nature.com
Nature Reviews Cancer - In this Journal Club, Basurto-Lozada and Robles-Espinoza discuss a study that challenges the prevailing view of a monoclonal origin of cancer by showing that early lesions...
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ICYMI π¨ In this month's #Focus issue on #AgeingandCancer, de MagalhΓ£es explores the evolutionary relationship between cancer & ageing, proposing that the need to minimize cancer risk early in life may contribute to tissue degeneration later. π π https://t.co/NRvx5eduZO
nature.com
Nature Reviews Cancer - In this Perspective, de MagalhΓ£es explores the evolutionary relationship between cancer and ageing, proposing that the need to minimize cancer risk early in life may...
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ICYMI π¨ In this month's #Focus issue on #AgeingandCancer, McAllister & colleagues discuss recent insights derived from age-resolved immunoprofiling of the TME and how ageing haematopoiesis affects immune cells and cancer progression. #REVIEW π π https://t.co/iA52GRrLhW
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ICYMI π¨ In this month's #Focus issue on #AgeingandCancer, Easwaran & Weeraratna outline how ageing leads to epigenetic alterations in the tissue microenvironment, enhancing clonal expansion of mutations + increasing cancer risk. #REVIEW π π https://t.co/ieCblTJRHN
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Looking for weekend reading material? π Check out this #Review from Ben Youngblood & Co outlining the epigenetic regulatory programmes that influence T cell differentiation fates and their implication for cancer immunotherapy. @StJudeResearch ππ https://t.co/juTSY1P4Ip
nature.com
Nature Reviews Cancer - Transcriptional and epigenetic mechanisms governing T cell exhaustion substantially impact immunotherapy effectiveness. In this Review, Kang et al. outline epigenetic...
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