
Nature Reviews Cancer
@NatureRevCancer
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Nature Reviews Cancer is a monthly review journal for researchers working on cancer. We, the editors, highlight the most exciting topics in cancer research.
London, UK
Joined November 2011
Our SEPTEMBER issue is live! π€οΈππ»π. It features articles on:.- ER stress responses in anti-cancer immunity.- Regulatory T cells in the TME.- Metabolic adaptations of brain metastasis .- Engineering strategies for nanoparticles.Read it nowπ.
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Stress and escape, inspired by the Review on p684.
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NEW content online! 3D chromatin architecture as a predictor of somatic mutations in cancer genomes
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Nature Reviews Cancer - In this Journal Club, Bansal and Mazumder discuss a study that investigated the interplay between three-dimensional genome structure and mutational load in cancer.
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Research Highlihgtπ¨ A viral wakeup call. Chia, Johnson et al. outline a mechanism for how pulmonary viral infections can awaken dormant disseminated cancer cells to enhance metastatic burden. πβ¬οΈ.
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Nature Reviews Cancer - Chia, Johnson et al. outline a mechanism for how pulmonary viral infections can awaken dormant disseminated cancer cells to enhance metastatic burden.
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In this #Correspondance, Ribeiro Junior & Claudino dos Santos, build upon Weichenthal (to emphasize that the geographic scope of wildfire impacts is even broader than the fire epicentres, owing to long-range smoke transport.
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π¨ REVIEW π¨ . #Ageing alters immune function and cancer outcomes. McAllister et al. explore how age-resolved immunoprofiling and models of ageing haematopoiesis reveal immune dynamics and new paths to optimize cancer therapy across age groups.
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Nature Reviews Cancer - Ageing reshapes immune composition, function and regenerative capacity, with profound effects on tumour immunity, cancer progression and treatment outcomes. In this Review,...
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Extreme weather events now impact communities once considered safe from climate hazards, posing challenges to cancer control efforts. Nogueira + Salas argue that the oncology community urgently needs to prioritize adaptation & mitigation actions.
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Nature Reviews Cancer - Recent extreme weather events have impacted communities once considered safe from climate hazards, posing growing challenges to cancer control efforts. Here, Nogueira and...
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#ResearchHighlight π¨ . Ben Sabari @bsabari &Co identified a common molecular signature in oncogenic fusion proteins that compartmentalizes RNA polymerase II to confer an increase in gene activation and consequent cancer phenotypes. πβ¬οΈ.
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Nature Reviews Cancer - Lyons et al. explored the rules of specificity and function for condensates formed by oncogenic fusion proteins, and identified a common molecular signature in these...
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NEW content online! No climate havens: the expanding threat of climate change to cancer care
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Nature Reviews Cancer - Recent extreme weather events have impacted communities once considered safe from climate hazards, posing growing challenges to cancer control efforts. Here, Nogueira and...
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#ResearchHighlight π¨ .In a recent study, the Nussenzweig lab @nussenza investigated the mechanisms underlying #cytarabine-induced neurotoxicity and provide a mechanistic explanation for the differing neurotoxicity profiles of #gemcitabine. πβ¬οΈ.
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Nature Reviews Cancer - In a recent study published in Nature, Liu, Wang, et al. investigate the mechanisms underlying cytarabine-induced neurotoxicity and provide a mechanistic explanation for the...
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π¨ Ageing-induced cellular #senescence influences cancer risk. In this #Review, Ye, Melam and Stewart @sastewartlab highlight the role of senescent stromal cells in cancer and the therapeutic implications of this.
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NEW content online! The overlooked global reach of wildfire smoke: beyond local health and cancer risk
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Nature Reviews Cancer - The overlooked global reach of wildfire smoke: beyond local health and cancer risk
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#ResearchHighlight . In a study published in #Cell, Phelps et al. find a mechanism connecting exercise, gut microbiota & anti-tumour immunity; exercise induces microbiota to produce formate, which in turn enhances CD8+ T cell functionality. π .
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Nature Reviews Cancer - In a study published in Cell, Phelps et al. find a mechanism connecting exercise, gut microbiota and anti-tumour immunity; exercise induces microbiota to produce formate,...
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#REVIEW π¨ . #Nanoparticles can be engineered for targeted delivery of cancer therapies. Gomerdinger, Nabar & Hammond explore how surface chemistry drives delivery, targeting & localization. π π .
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Nature Reviews Cancer - Nanoparticle surfaces can be engineered for targeted delivery of cancer therapies. In this Review, Gomerdinger, Nabar and Hammond outline the role of surface chemistry at...
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