Iannis Aifantis
@iannisaifantis1
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Cancer & Immunology Research. Professor & Chair, @NYUGSOM_Path @nyugrossman. All opinions are my own only. Visit me also on @instagram and @LinkedIn.
New York City, NY
Joined October 2015
Excited to share with all our latest work on the use of single cell tools in following IDH mutant AML patients during their treatment! Out today @CellStemCell !! An amazing collaboration with @AkEisfeld & @PapaemmanuilLab & @landau_lab !!! Driven by the impressive @MariaSirenko
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More highlights from Day 1 of the AML-ALL EU Focus Meeting 2025 in Athens. Sign up to watch the full meeting recording: https://t.co/YJQzX5NdQY
#Hematology #Oncology #AML #ALL #Leukemia @Daver_Leukemia @sanamloghavi @charliecraddock @cpapayannidis
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Fantastic news for AML patients with the extended approval of Revumenib for R/R NPM1m AML! Congrats to all investigators & those on the frontlines! We are truly in a new era of targeted therapies for AML 👏👏👏
Revumenib is now @US_FDA ✅ for R/R AML w/ NPM1 mutation (approved for KMT2A translocation previously). - ORR 46.9% - Response seen in all subgroups (comutations, previous HSCT, or high number of prior lines of Rx). #HemeTwitter @beatalleukemia @LeukDocJZ 👏👏
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Last day of @FEBSnews workshop on aging in hematopoiesis in beautiful Crete. So many inspiring talks! Great to meet colleagues and new young scientists. Inspiring science in the sun- what more can you wish for? Many thanks and congratulations to the organizers!
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The Skok Lab is recruiting an experienced computational scientist to lead single-molecule epigenomic and 3D genome analysis. We integrate long-read sequencing with Hi-C/Hi-ChIP, scmulti-omics, and machine-learning to explore chromatin topology, and gene regulation.
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🚨Our new paper is out today in Nature! We show that SARS-CoV-2 mRNA vaccines can sensitize tumors to immune checkpoint blockade (ICI) — revealing that clinically available RNA vaccines may act as potent immune modulators.
nature.com
Nature - mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.
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Inspired by last night’s @CancerResearch Institute gala and the amazing community dedicated to advancing cancer research. Honored to be a CRI Fellow! Thank you for your support! ✨
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Join us on November 25th, online, to discuss 3D nuclear organization, gene transcription and human cancer! Organized by @jane_skok and @NYUGSOM_Path !!
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As the weather turns chilly and the leaves start to fall, our @nyugsom_path residents took to Queens County Farm Museum for a “Maze by Moonlight” Corn Maze activity! We found all the clues to finish the maze and learned some “Kernals of Knowledge” along the way too! Happy Fall!🎃
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Excited to be this week at the "Aging and Hematopoiesis" workshop organized by @FEBSnews on the beautiful island of Crete in Greece! An amazing line up of speakers!
Register today for the FEBS Workshop on Aging in Hematopoiesis that will take place in Crete on 20-24 October 2025. An outstanding scientific program in a beautiful location! More information: https://t.co/9kdAeJCWCf
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Ever wondered how the 3D shape of DNA influences nucleosome spacing along chromatin? Dr. Vijay Ramani from the Gladstone Institute, will reveal fresh, unpublished insights on this topic, featuring a new method – LASSI – that tracks single-molecule sequence interactions in 3D.
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🔍 New study from @ALLIANCE_org and AML Cooperative Group asks: Are age-based treatment classifications for #AML outdated? 🔻 5yr OS by age: 73% (ages 18–24) to 21% (≥75) @AkEisfeld suggests a shift toward biology-driven eligibility over age thresholds. https://t.co/WhEzFuj7Fl
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Congratulations to one of the best physicians, scientists, collaborators and friends out there! Such a great choice for MSKCC!
Dr. Ross Levine (@rosslevinemd), Senior Vice President of Translational Research at MSK, has been named MSK's new Chief Scientific Officer (CSO). Dr. Levine will be responsible for setting and leading strategy for basic and translational research, including programs, centers,
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Very cool study by @glytsou (with some help from our lab and @LabScorrano ) targeting OPA1 in AML and combining it with BH3 mimetic treatment! #drugresistance #leukemia #Venetoclax
Big news from the #Glytsoulab today!✍️Our research on drug resistance in leukemia is published in @ScienceAdvances. Targeting OPA1 can help overcome therapy resistance in AML, including the most challenging cases. 📖
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A paper many years in the making across multiple labs and institutions! Transient skin inflammation can have profound influence in reprogramming immune responses globally! @AWeinstock @iannisaifantis1 #teamworkdreamwork
Out today the last piece of work that Maria Guillamot did in our lab in a collaboration with @AWeinstock and @DrShrutiNaik (who lead the study) showing type I interferon (IFN)-mediated activation of hematopoietic stem/progenitor cells resulting in profound changes to systemic
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Your immune system remembers skin inflammation long after it resolves because of #interferon alpha! Check out our new paper describing these findings just published at @J_Immunol 👇👇👇 https://t.co/RbLNEsIrAY
academic.oup.com
Abstract. Inflammation has enduring impacts on organismal immunity. However, the precise mechanisms by which tissue-restricted inflammation conditions syst
Out today the last piece of work that Maria Guillamot did in our lab in a collaboration with @AWeinstock and @DrShrutiNaik (who lead the study) showing type I interferon (IFN)-mediated activation of hematopoietic stem/progenitor cells resulting in profound changes to systemic
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Out today the last piece of work that Maria Guillamot did in our lab in a collaboration with @AWeinstock and @DrShrutiNaik (who lead the study) showing type I interferon (IFN)-mediated activation of hematopoietic stem/progenitor cells resulting in profound changes to systemic
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BREAKING NEWS The Norwegian Nobel Committee has decided to award the 2025 #NobelPeacePrize to Maria Corina Machado for her tireless work promoting democratic rights for the people of Venezuela and for her struggle to achieve a just and peaceful transition from dictatorship to
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Join @BiolaMJavierre as she unveils the first-ever gene regulatory roadmap of human B cell differentiation – linking chromatin architecture, enhancer activity, and disease risk across nine B cell subtypes. n
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It has been a pleasure and honor working with @DrTonyLetai as @BCD_AACR Scientific Editor, and author of this 2024 article published simultaneously with his talk at the inaugural Blood Cancer Discovery Symposium:
aacrjournals.org
AbstractIn many cancers, mortality is associated with the emergence of relapse with multidrug resistance (MDR). Thus far, the investigation of cancer relapse mechanisms has largely focused on...
The AACR congratulates Anthony Letai, MD, PhD, on his appointment as the 18th Director of the National Cancer Institute. We look forward to working with Dr. Letai and the NCI to advance our shared mission to prevent and cure all cancers. https://t.co/CVERcaZ6cQ
@theNCI
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