Nature Metabolism
@NatMetabolism
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Nature Metabolism publishes studies that advance our understanding of metabolic and homeostatic processes in physiology and disease.
Berlin, Germany
Joined December 2017
✨New issue✨ Check out the latest in #Metabolism research from across all disciplines. Read about #DietarySugars, #Drosophila development, #Exenatide, #Ketone metabolism, #Neurolipids, #NAD+, #RedoxPathways, and many more topics! https://t.co/ywYqOW4RSi
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#Throwback PERSPECTIVE | W Wu, GA Sunagawa & H Chen Synthetic torpor: advancing metabolic regulation for medical innovations https://t.co/Rh1IiMCcvP
nature.com
Nature Metabolism - Chen et al. provide an overview of historical and more recent approaches for the induction of synthetic torpor, and discuss their potential medical applications.
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🚨Job Alert! 🚨 Last chance to apply! @NatMetabolism seeks an #Editor to join our team and work in collaboration with @NatureComms 🧪🧑💻 If being a Editor is for you, check out our #job posting below and apply before Oct 26th! Locations: US, China. Details below!
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RESEARCH | CM Metallo, T Cordes et al. (Salk, TU Braunschweig) Tracing of circulating itaconate in vivo to gain insight into its fate and systemic metabolism. https://t.co/C35vW1mQPD
nature.com
Nature Metabolism - In this study, Willenbockel et al. trace circulating itaconate in vivo to gain insight into its fate and systemic metabolism.
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#Throwback COMMENT | @nutsci, L Golzarri-Arroyo & DB Allison A brief guide to statistical analysis of grouped data in preclinical research https://t.co/6j9bSHOxBD
nature.com
Nature Metabolism - Clustering and nesting (C&N) arise in many preclinical studies, such as when animals are group-housed or share litters, or in cell culture. Ignoring C&N...
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#Throwback METABOLIC MESSENGERS | Oestradiol AL Hevener & SM Correa https://t.co/rH6MMffNqG
nature.com
Nature Metabolism - Hevener and Correa provide a comprehensive overview of the preclinical and clinical evidence showing the metabolic role of oestradiol and its receptors in both women and men.
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RESEARCH | R Liu, H Shen et al. (@Yale) A new method enables a thorough characterization of coenzyme A dynamics and subcellular partitioning. https://t.co/co7dbBV6ig
nature.com
Nature Metabolism - By developing a method that allows detection of transient, low-abundance acyl-CoA species, Liu et al. provide a thorough characterization of coenzyme A dynamics and subcellular...
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🚨Job Alert! 🚨 @NatMetabolism seeks an #Editor to join our team and work in collaboration with @NatureComms 🧪🧑💻 If being a Editor is for you, check out our #job posting below and apply before Oct 26th! Locations: US, China. Details below! https://t.co/2LMeCscDxY
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Sweet signals for myelin: glucose sensing redirected to regeneration
nature.com
Nature Metabolism - Oligodendrocyte progenitor cells harness aldolase C–TRPV–AMPK signalling in a bespoke way to sense glucose availability and prioritize energy towards remyelination.
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Oligodendrocyte precursor cell-specific blocking of low-glucose-induced activation of AMPK ensures myelination and remyelination
nature.com
Nature Metabolism - Inhibition of AMPK activation under low glucose conditions in oligodendrocyte precursor cells is shown to be important for myelination during development and remyelination in...
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#Throwback REVIEW | M Van Hul, P Cani et al. The gut microbiome and cancer: from tumorigenesis to therapy https://t.co/H36yT0bxME
nature.com
Nature Metabolism - This Review discusses the impact of the gut microbiota on cancer and on cancer therapy, highlighting the importance of developing microbiota-targeting strategies to improve...
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RESEARCH | J Bonnereau, P Agostinis et al. (@KU_Leuven) BDH2 participates in iron distribution between cellular compartments, which sets the threshold for the ferroptosis vulnerability of melanoma cells. https://t.co/0sHM68iSYx
nature.com
Nature Metabolism - Rizzollo et al. show that BDH2 participates in iron distribution between cellular compartments, which sets the threshold for the ferroptosis vulnerability of the melanoma cell...
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Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4+ T cells to confer protection against intestinal inflammation
nature.com
Nature Metabolism - The gut microbiota-derived metabolite indole-3-propionic acid (IPA) is found to enhance mitochondrial fatty acid and amino acid oxidation in CD4+ T cells. In mice,...
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#NatMetabPicks | In @ScienceMagazine led by J Zuber (@IMPvienna) and W Palm (@DKFZ) Acidosis induces mitochondrial fusion by suppressing cytoplasmic ERK signaling, which increases cancer cell resilience to metabolic stress. https://t.co/SrOBNbiDPj
science.org
Malignant tumors are characterized by diverse metabolic stresses, including nutrient shortages, hypoxia, and buildup of metabolic by-products. To understand how cancer cells adapt to such challenges,...
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#Throwback REVIEW | @AnneloftSdu, M Emont, E Rosen et al. Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution https://t.co/9hp00mRnoM
nature.com
Nature Metabolism - In this Review, the authors present a roadmap towards achieving consensus on development, analysis and interpretation of single-cell transcriptomics data in adipose tissue,...
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A lactate–acetate interaction between macrophages and cancer cells drives metastasis
nature.com
Nature Metabolism - Cancer cells often increase their uptake of acetate for acetyl-coenzyme A biosynthesis, a mechanism that facilitates cancer metastasis. We found that, in hepatocellular...
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Tumour-associated macrophages serve as an acetate reservoir to drive hepatocellular carcinoma metastasis
nature.com
Nature Metabolism - Acetate accumulation and metastasis of hepatocarcinoma cells is driven by a metabolic interaction involving HCC-derived lactate and acetate secretion from tumour-associated...
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#Throwback COMMENT | KS Lee, X Su & T Huan Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics https://t.co/YlaTvcsM4Q
nature.com
Nature Metabolism - Pathway analysis, originally developed for gene expression data, has been adapted for metabolomics. However, owing to the unique characteristics and constraints of metabolites...
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RESEARCH | S Benhmammouch, @yvancharvet et al. (Univ Côte d’Azur) Glutamine uptake and utilization regulates macrophage function in atherosclerosis. https://t.co/0gxFqRw88s
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