Waggoner Lab
@LabWaggoner
Followers
11K
Following
7K
Media
8K
Statuses
31K
Research lab of Dr. Stephen Waggoner. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer. @labwaggoner.bsky.social
Cincinnati, OH
Joined August 2018
Congrats @CincyImmunology @AndypedsId.@HAFeldman17 @VijayVelu77 @tuazonjasmine @allisonyan @_Ayad_Ali .Refined cell transfer model reveals roles for Ascl2 and Cxcr3 in splenic localization of mouse NK cells during virus infection.@J_Immunol
Excited to share preprint (currently in revision) from the PhD dissertation of my former @CincyImmunology student LC. Thanks to @AndypedsId, @HAFeldman17 @VijayVelu77, @tuazonjasmine, @allisonyan @_Ayad_Ali and the rest of the team for their hard work.
1
3
31
Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies @JExpMed .
0
0
0
Targeting intestinal inflammation using locked nucleic acids delivered via lipid nanoparticles @NatureComms @peer_lab @QassemShahd.
0
0
1
RNA N6-methyladenosine reader protein YTHDF2 is a negative regulator of T helper 9 (TH9) cell differentiation and effector function @NatImmunol .preview by @statfourwork
0
0
0
Review @NatImmunol @eickelatz @aweberlab.The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets.
0
1
2
Regulatory T cell therapy promotes TGF-β and IL-6-dependent pro-inflammatory Th17 cell generation by reducing IL-2 @NatureComms .
2
26
108
Hepatic arterial infusion chemotherapy promotes tertiary lymphoid structures formation in HCC, enhancing anti-tumor immunity and patient outcomes.@CellRepMed
1
5
18
Nasopharyngeal carcinoma-specific SOX4 regulates zinc metabolism via ZIP14, promoting tumor growth and creating a zinc-deficient niche that impairs CD8+ T cell function @CellRepMed .
0
0
6
High-dose ascorbic acid selectively induces pyroptosis in lung cancer with LKB1 deficiency via the ROS-caspase-3-GSDME axis @CellRepMed .
0
1
5
A genetically encoded CXCL10 sensor to visualize the state-specific CXCL10 dynamics across multiple systems, revealing how its spatiotemporal features translate environmental information during inflammation @ImmunityCP .
0
16
113
Review @TrendsImmuno @buonagurol @Jamie_Rossjohn.Molecular mimicry as a driver of T cell-mediated tumor immunity.
0
6
45
Turning the tide in peritoneal metastases: Locoregional CAR-NK therapy primes systemic immunity in colorectal cancer @MolTherapy @dow072109.
0
1
8
Congrats @jazibuddin!.CGRP-related neuropeptide adrenomedullin 2 promotes tissue-protective ILC2 responses and limits intestinal inflammation @NatImmunol .
1
6
50
ICAM-1 identifies preadipocytes and restricts white adipogenesis by adhering immune cells @cddpress .
0
0
7
CCR7+ dendritic cells expressing both IL-23A and IL-12B potentially contribute to psoriasis relapse @NatureComms .
0
0
10
Brain editing now ‘closer to reality’: the gene-altering tools tackling deadly disorders @Nature .
0
5
12
Cancelling mRNA studies is the highest irresponsibility.The rest of the world is not following the US government’s dangerous path, and will stick with the technology that helped the world out of the COVID-19 pandemic @Nature
0
0
2
Beyond lab animals @ScienceMagazine @Sara_Reardon.With a boost from the Trump administration, organ chips, AI, and other technologies bid to replace animals for drug and chemical testing.
science.org
Drug and chemical safety can be assessed with AI and organ chips, but some scientists say it’s too soon to forgo animal methods entirely
0
2
3