I’m beyond excited to share that I’ll be starting my own lab at the University of Wisconsin–Madison School of Pharmacy @UWMadPharmacy in Jan 2026! So grateful to everyone who’s supported me along the way—especially my postdoc advisor Alice Ting @aliceyting. Can’t wait to start

Hooray!! The first major product from the lab is out today @Nature. Small molecules that bind the GPCR-transducer interface change G protein subtype selectivity in predictable ways, enabling rational drug design.💥 Check it out! 👉 https://t.co/oO21BkoxVQ 🧵👇

I don't understand how someone can read this and not think that the American biomedical research system is a modern miracle that should be protected at all costs

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @DjenetBousbaine led the charge... @Nature 1/55

The 5th Rising-star Seminar Series by @nkalogriopoulos January 8, 6pm of California time Join via Zoom on QR code His cool work on synthetic GPCR on Nature

So excited to share our work developing a new class of modular synthetic GPCRs, out today @Nature! Check it out https://t.co/vELPS7Ftcu Synthetic receptors that mediate antigen-dependent cell responses are transforming therapeutics, drug discovery and basic research. However,

Congrats to the team: especially @gori7873 and Brian Krumm from @RothLabUNC and Adrien and Matan from Greg Scherrer's lab!! A ton of work! Structure-guided design of a peripherally restricted chemogenetic system: Cell

Happy to share the lab’s latest research tagging psychedelic-activated neurons in mice. See the post below from first author @jessie_muir for a tweeprint on the work. Thanks to wonderful collaborators @DEOlsonLab @LinTianPhD and to our reviewers/editor! https://t.co/Gt6iGbLWdn

Doing good science is 90% finding a science buddy to constantly talk to about the project.

(1/4) Did you know that there are bacteria in human tumors? Well, this is old news now 😊. Our new study, featured on the cover of @CellCellPress, shows that human tumors contain fungi as well and that tumor fungi matter! (Cover by @munafomarzia) https://t.co/gQA3olwSpO

Today in partnership with @emblebi, we’re releasing predicted structures for nearly all catalogued proteins known to science, which will expand the #AlphaFold database by over 200x - from nearly 1 million to 200+ million structures: https://t.co/GjVES2pBFY 1/

The world's most valuable skill: Clarity of thought. The problem? There's no school for this. It takes time, patience and a lot of early career fumbling. Here are 10 cognitive distortions I faced early in my career and an insight on how to break through each one:

Happy to share the @biorxivpreprint for my first bit of work w/ @aliceyting. Together with @heegwangroh, we built a simple and versatile single-component luminescent biosensor for detecting the SARS-CoV-2 spike protein. https://t.co/GPU8D4MwlA

Out in @CellCellPress! Our collaborative team @jasonzxzhang @RangamaniUCSD & Susan Taylor discovered that cAMP induces and is sequestered into membraneless organelles formed by a regulatory subunit of PKA, important for suppressing tumorigenic signaling. https://t.co/xDLohhPb1K

AMAZING! "Thus, de novo designed proteins can perform computations on the surface of cells, integrating multiple distinct binding interactions into a single output."

Split-TurboID out @ PNAS! Reconstitution across mito-ER contacts in HEK IDs 101 proteins, incl. 8 novel ones we validated by MAM purification or imaging. https://t.co/HUky4SvWMG One of my favorite figures shows intracellular split-TbID reconstitution driven by cell-cell contact:

Split-TurboID enables conditional proximity labeling w/even greater spatial specificity than TurboID. We reconstituted split-TurboID across ER-mito contacts & enriched 101 human proteins, many of which have not prev. been linked to mito-ER contact sites. https://t.co/uWGCTW5iwL

Grad students, this time of year can mean extra intense comparison to friends or family your age who took jobs right out of college. Remember that their path is not your path. Stay focused on your long-term goals and the things that you are proud of having accomplished. #PhDchat

Faculty, next time you ask a student or postdoc “how is your research going?” try following up with “and how are *you* doing?” Showing that we care about people does not mean that we care any less about research, and it can make a big difference in someone’s day.

#salute We salute the mom who made sure her son who has cerebral palsy — and who wanted to skate — got to do just that. See the next tweets for the details: 1/3