New research in Science greatly expands the potential target scope of molecular glues and should stimulate the development of new small molecules that can selectively target therapeutically relevant proteins for degradation. Learn more in this week's issue:

“GlycoCaging” uses gut bacteria to activate drugs for inflammatory bowel disease. Learn more in a new #SciencePerspective:

By measuring pupil response in 8-month-olds, a new study finds that infants can actively adapt their learning in response to volatility in their environment. The ability to adapt varies between infants, possibly linked to temperament. @ScienceAdvances

The Vera C. Rubin Observatory is set to transform astronomy. Its wide and fast survey will discover billions of dynamic objects while building up a deep map of the universe. Learn more:

RT @NewsfromScience: Exclusive: A major scientific publisher, Taylor & Francis, said it has paused submissions to its journal Bioengineered….

When pursuing science education or work abroad, what is the biggest challenge you face? What one change would help scientists from your country or region overcome this challenge?. #NextGenSci asked—here's how you responded:

🎉 Congratulations to Djenet Bousbaine, winner of the 2025 NOSTER & Science Microbiome Prize for her work to illuminate how the immune system responds to the beneficial skin microbiome. Learn more:

RT @NerdyChristie: Cheese really might give you strange dreams—especially if you have a sensitivity to dairy. That and more of the best in….

A 2024 #SciencePerspective highlights the growing body of evidence that hints at the potential of GLP-1–based medications in treating conditions other than diabetes and obesity, including cardiovascular disease and neurodegenerative disorders. Read more:

Older patients with lupus display a marked drop in the expression of interferon stimulated genes and shifts in methylation epigenetic patterns, according to a clinical study that may explain why the condition becomes milder with age. @ScienceTM

"By fostering collaboration across disciplines and prioritizing equitable deployment, agriphotonics has the potential not only to monitor but to actively shape plant productivity …," writes Xiaobo Yin in a new #ScienceExpertVoices article.

Hundreds of hidden fossils reveal squids’ evolutionary origins. Learn more: @NewsfromScience

Using an innovative “digital fossil-mining” approach, researchers in Science have uncovered hundreds of previously hidden fossil squid beaks, revealing a record that squids originated and became ecologically dominant roughly 100 million years ago—well before the end-Cretaceous

A new delayed delivery platform for malaria vaccines based on polymer microcapsules can deliver both prime and booster doses of the R21 vaccine in a single shot, leading to strong antibody responses in mice. Learn more in @ScienceTM:

"I no longer see reinvention as a deviation from a plan. It has become the most transformative force shaping my path." #ScienceWorkingLife

In @scisignal, researchers identify a molecular hub in neuronal dendrites that shapes the plasticity of synapses and find that the loss of these dendritic scaffolds might play a role in mouse models of Alzheimer's disease.

Natural hazards such as earthquakes, fires, and floods can dramatically affect human life and infrastructure. In a new #ScienceReview, researchers argue the need for a unified, interdisciplinary approach to studying cascading land surface hazards.

Why does Roux-en-Y gastric bypass reduce the risk of colorectal cancer?. New work in mice and patients shows that the procedure diverts bile acids and shifts the bile acid profile in serum, leading to antitumor and antimetastatic effects. @ScienceTM

The newly discovered microbe provisionally known as Sukunaarchaeum isn’t a virus. But like viruses, it seemingly has one purpose: to make more of itself. Learn more: @NewsfromScience

RT @ScienceTM: A new classification system may predict outcomes in patients infected with severe mpox, scientists uncover the secret to rap….