Jessica Zhao
@jesszhiyuezhao
Followers
217
Following
1K
Media
2
Statuses
132
PhD candidate @brangwynnelab @princeton chem. & bio. eng, previously @ucla
Princeton, NJ
Joined November 2018
Excited to share that the first paper of my PhD work in @brangwynnelab is out! In this work @NatureComms, we focus on how condensates in the cell nucleus respond to mechanical deformation during cell confined migration, a process involved in cancer cell metastasis. (1/3)
3
14
70
@amsikking Volumetric imaging of 384 wells in a contact free format using an air lens. Importantly, the 3D imaging remains diffraction limited and distortion-free, despite the large refractive index mismatch from air to water.
2
1
6
Happy to share a new preprint! Ebola virus condensates don’t just contain viral RNA🧬 — they also capture and regulate host mRNAs , reshaping interferon responses and viral adaptation. #Virology #RNA #Condensates
https://t.co/FEgR2m9WSp🧵👇
1
8
22
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: https://t.co/84lDgRTJgc
5
21
86
I’m thrilled to share our preprint that uses deep learning to interrogate structure-function relationships in condensates! https://t.co/izhFI1ANXa In here, we ask: can AI read condensate biology from pictures alone? Turns out yes... see what we discover below! 🤖🧬🖼️ (1/10)
biorxiv.org
Biomolecular condensates compartmentalize the interior of living cells to spatiotemporally organize complex functions, yet linking molecular interactions within condensates to their mesoscale...
1
12
39
Real-time feedback control microscopy for automation of optogenetic targeting https://t.co/lJy7BIZQwa
#biorxiv_cellbio
biorxiv.org
Optogenetics have revolutionized our ability to study cellular signaling by enabling precise control of cellular functions with light. Most classical implementations rely on fixed or manually updated...
0
2
8
Our squid primary cell isolation protocol is now out in @STARProtocols ⭐️🦑🧫This protocol enables molecular studies of cephalopod biology, aging, and basic cell physiology. Thanks to @brangwynnelab @HaileyTanner26 @JoshRosenthal16 check it out here https://t.co/DRq99soazt 🤩
HNY! In case you thought 2025 is the year of the snake, it's actually the year of the SQUID🦑Excited to present this new protocol paper from the @brangwynnelab on isolating+transfecting squid primary cells🧫✨! Check it out here:
3
6
39
FINALLY! This was challenging to publish but we believe it is an important discovery: https://t.co/lN4KQqfIC6 💫Thanks to the amazing team 💫 @bis_was_here @Omar136661 @KyoohyunK Carsten Hoege Benjamin Lorton @RainerNikolay @MatthewKraushar
@DShechter @GuckLab @VasilyZaburdaev
6
32
101
WORK! My lab currently have 5 (!) open positions for postdocs/PhD students for: -Nanopore protein sequencing -Archaeal CDV cell division -Microfluidics for synthetic cells -Nuclear Pore Complex -Origami mimics of peroxisomes Please apply! https://t.co/t4Yk0aZLHF RT=👍
4
66
123
The federal government’s demand of $1 billion from @UCLA would devastate the nation’s best public university, cut off life-saving care, halt tech and economic growth, and reduce educational access. Stand with UC to protect our students, staff, faculty and our vital mission:
universityofcalifornia.edu
The federal government’s demand of $1 billion from UCLA puts the entire University of California system at risk. Stand with us to protect UC.
4
14
52
“As a public university, we are stewards of taxpayer resources, and a payment of this scale would completely devastate our country’s greatest public university system as well as inflict great harm on our students and all Californians.” —UC President James B. Milliken
Breaking News: A Trump administration settlement proposal demands more than $1 billion from UCLA. It calls for the payout to contribute to a claims fund that would compensate victims of civil rights violations after a pro-Palestinian protest on campus.
9
68
195
Check out our most recent published paper in @NatureComms about the effects of cell surface crowding in cell-cell fusion:
0
5
13
How the material properties of nucleoli relate to their ribosome-maturing function 📹 Holly H. Cheng et al @Princeton in @PNASNews 📷 https://t.co/maNRVLqlNO with @DrJohnAnkers
0
6
29
Excited to share our new preprint on @biorxivpreprint from our great team @EMBL! https://t.co/JaeFubrQWd If the nucleolus is liquid-like, why does it often appear irregularly shaped in proliferating mammalian cells? What controls the nucleolar shape? #PhaseSeparation #Nucleolus
3
32
130
Everyone working in a STEM field should read this - ‘writing is thinking’ https://t.co/pps0zyCURe
79
1K
6K
Grateful to have contributed to this piece- check out our new manuscript on how chromatin meshwork controls phase separation of nuclear condensates 🧬
Congrats to Jing @jesszhiyuezhao & @DNAmyStrom on cool manuscript!!! Reveals how cell nucleus is a heterogeneous material, w chromatin organization controlling formation & phase behavior of nuclear condensates. #CellBiology #Chromatin #PhaseSeparation
0
0
9
Experimental biophysicist Joshua Shaevitz and quantitative biologist Britt Adamson have joined the Omenn-Darling Bioengineering Institute as associated faculty members. Welcome! More: https://t.co/qWyLaBu4F0
0
1
2
Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior. Congratulations Jing! Happy to have contributed in a small way to this interesting work! https://t.co/OZHRknyFV4
nature.com
Nature Communications - Chromatin heterogeneity in the cell nucleus modulates the size, mobility, and formation of biomolecular condensates; decreasing chromatin heterogeneity correlates with...
1
16
113
It was a pleasure working with the amazing physio students over the past two weeks! Such an honor to be part of this immersive scientific community @MBLScience ❤️
0
0
10
So proud of @XiangyiDing from the Starr-Luxton lab featured in @NatureMethods! The collaborative spirit she describes captures what we're creating through our @PaulGAllenFront supported work with @DanielStarr9 at @UCDavis #Frontierscience
https://t.co/6HKygVxUZ6
nature.com
Nature Methods - Some graduate students, postdoctoral fellows and senior researchers choose a special kind of science-focused summer.
1
2
9