Nature Methods
@naturemethods
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Nature Methods publishes cutting-edge methods, tools, analyses, resources, reviews, news and commentary, supporting life sciences research. Tweets by editors.
New York
Joined March 2011
MIHCLE: minimum information about a high containment laboratory experiment. Reporting standards for experiments with pathogens in BLS-3 and -4 laboratories. https://t.co/4tEVKUwIgQ
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Deep Imputation for Skeleton data (DISK) imputes missing animal tracking keypoints in videos and motion capture recordings. @bozeklab
https://t.co/L7T6tYTDkj
nature.com
Nature Methods - Analysis of behavioral data often involves tracking animal keypoints in video and motion capture recordings. DISK imputes missing keypoints, thereby improving downstream analyses.
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LatentSNA is a method for network analysis in human neuroimaging, that links neural activity with behavior. https://t.co/h90Q9y3aSe
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C-COMPASS: a tool to predict spatial cellular distribution of proteins and lipids. https://t.co/LjD2sVpajR
nature.com
Nature Methods - C-COMPASS is an open-source software designed to predict the spatial cellular distribution of proteins and lipids from cellular organelle profiling using a neural network-based...
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RFdiffusion2 builds de novo enzyme active sites using atom-level functional group constraints. https://t.co/a9CrE1dS5v
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CaBLAM: a bioluminescent, genetically encoded calcium indicator for high-contrast imaging in cells and in vivo. @_theglowup @NathanShaner @BiolumHub @ADC_NeuroEnv
https://t.co/WXyV8AeAaa
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Parallelized single-molecule fluorescence and FRET experiments enable quantitative analysis of molecule function from multiple samples in a single experiment. @TheBlanchardLab
https://t.co/dNUYpuFStZ
nature.com
Nature Methods - Parallelized single-molecule fluorescence and single-molecule FRET experiments enable quantitative biophysics investigations of molecular function from multiple samples in a single...
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ROSE-3D is a single-molecule localization microscopy method with high isotropic resolution, for whole-cell and multicolor imaging. @WeiJi94835972
https://t.co/Ui3p2P8n9K
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An Analysis benchmarks 50 state-of-the-art TCR-epitope binding prediction methods. https://t.co/Aatp5qrmTh
nature.com
Nature Methods - This Analysis benchmarks 50 state-of-the-art TCR–epitope binding prediction methods and evaluates key factors that influence predictive performance.
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ExoSloNano: nanogold probe-based labeling of proteins in live cells for cryo-ET and CLEM. @lindsey__young @thevillalab
https://t.co/ob4I95wfX3
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We are looking for a new editor with expertise in genetics, genomics and/or molecular biology to join our editorial team in the US (NYC/Jersey City) or China (Shanghai/Beijing)! Only 2 days left to get your applications in! https://t.co/zxh4dyTyDx
https://t.co/RPNGduUgVi
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Method of the Year 2025: In her feature, @metricausa asks scientists about their strategies and decision-making as they scale EM-based approaches for larger brains. https://t.co/NowgFr63Vq
nature.com
Nature Methods - Using electron microscopy, scientists mapped a Caenorhabditis elegans nervous system and Drosophila brain at single-neuron resolution. Connectomics work on bigger brains takes new...
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Method of the Year 2025: In his Comment, Moritz Helmstaedter @mh_lab looks into the future of connectomics and the feasibility of scaling up to larger brains. https://t.co/iafRUt3LjT
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Method of the Year 2025: In their Comment, Wei-Chung Allen Lee @darbly and Ramin Khajeh discuss alternatives to the well-established approaches used in connectomics. https://t.co/1SVSZyrUmq
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Method of the Year 2025: In his Comment, @janfunkey discusses current challenges in connectomics, which is time-consuming and labor-intensive. He focuses on proofreading and discusses how automated models might be further developed to embrace uncertainty. https://t.co/uL5ynHxB9B
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Method of the Year 2025: A Comment from @martamcosta2 discusses challenges and prospects of comparative connectomics, which provides insights into variability between individuals, changes during development, differences between sexes and evolutionary changes between species.
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Method of the Year 2025: In his Comment, @rclayreid discusses functional connectomics, which links structure and function by combining electron microscopic reconstruction of brain tissue with calcium imaging of neuronal activity. https://t.co/3gbE2vw3ku
nature.com
Nature Methods - Functional connectomics is a new approach, involving calcium imaging of neuronal activity followed by correlated electron microscopy connectomics of the same neurons, that relates...
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