Abin Biswas
@bis_was_here
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Postdoc w/ @GuckLab & @SimoneReber @MPI_Light + @mpiib_berlin Investigating the intersection of biology & physics by day, dreaming of butter chicken by night.
Berlin
Joined December 2009
Hi there fellow #cellbiology, #biophysics and #devbio afficionados! Have you ever wondered how intracellular densities vary within cells? Are you curious about the effect density distributions have on cellular organization? Our latest preprint might have some answers. (1/15) …
How dense is the nucleus? Check our preprint "Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes" https://t.co/q2ceSs8X5s ✨Congrats @bis_was_here Omar Muñoz @KyoohyunK Carsten Hoege @HymanLab @DShechter @GuckLab @VasilyZaburdaev✨
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Come to Heidelberg!
⏰ Final call for abstracts for #EESNucleus! 📥 Submit your abstract by 26 August: https://t.co/GnkTzsQ1bb Come and join the brand new EMBO | EMBL Symposium: 'Cell biology of the nucleus' 🌟 Don't miss your chance to discover the cutting-edge research shaping our understanding
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FINALLY! This was challenging to publish but we believe it is an important discovery: https://t.co/lN4KQqfIC6 💫Thanks to the amazing team 💫 @bis_was_here @Omar136661 @KyoohyunK Carsten Hoege Benjamin Lorton @RainerNikolay @MatthewKraushar
@DShechter @GuckLab @VasilyZaburdaev
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Finally is an important word - and perhaps it reflects how non-trivial this finding was! Thanks and congrats to the whole fine team!
FINALLY! This was challenging to publish but we believe it is an important discovery: https://t.co/lN4KQqfIC6 💫Thanks to the amazing team 💫 @bis_was_here @Omar136661 @KyoohyunK Carsten Hoege Benjamin Lorton @RainerNikolay @MatthewKraushar
@DShechter @GuckLab @VasilyZaburdaev
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It's here! AND It's become better 🐸 Our fundamental work on intracellular density distributions, how it influences cellular organisation & how deviations occur during pathophysiological states like senescence is in @NatureComms Congratulations & thank you to the whole team!
FINALLY! This was challenging to publish but we believe it is an important discovery: https://t.co/lN4KQqfIC6 💫Thanks to the amazing team 💫 @bis_was_here @Omar136661 @KyoohyunK Carsten Hoege Benjamin Lorton @RainerNikolay @MatthewKraushar
@DShechter @GuckLab @VasilyZaburdaev
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Congratulations to everyone involved!!! 🍾🎉🤩 Fortunate to have contributed to this beautiful work demonstrating how cytoplasmic density tunes mitotic spindle architecture 🔬📈🐸
✨Thanks to amazing students @TobiasKletter @MrEnkapsis, postdocs @bis_was_here & collaborators @Omar136661 @VasilyZaburdaev ALMF @EMBLHeidelberg ✨ 👉Cytoplasmic material properties control spindle architecture and scaling 👉out today @NatureCellBio
https://t.co/GJ3TAqkRmy
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Investigating spatio-temporal dynamics in the complex cytoplasm using label-free tools 🔬 and 🐸 extracts. Beautiful work by @MockelConrad Congratulations! 🎉🍾
🔍Exploring cytoplasmic dynamics! Our study reveals hierarchical heterogeneities in Xenopus egg extracts using #DDM 🐸🔬. Macromolecules, energy, and the cytoskeleton each play a role. Check out our new preprint: https://t.co/4CjHnn731J
@GuckLab @MPI_Light @MPZ_PhysMed @UniFAU
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Congrats to Mirko Pleitner for the FEBS Letters Poster Award! Mirko from the lab of @SimoneReber at @HumboldtUni presented an excellent poster at the @EMBO @embl Symposium "Wild frontiers of model organisms". Thanks for the fantastic insights! #EESWildModels @EMBLEvents
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How did microtubules adapt to support life across 🐸species at divergent thermal niches? Now online & OA @CurrentBiology Thanks to @elladegaulejac @luca_troman @bis_was_here @CarolynMoores1 @mpiib_berlin @BirkbeckUoL 🙌 Enjoy reading! 👉
cell.com
Despite tubulin’s evolutionary conservation, microtubule dynamics are highly temperature sensitive. Troman et al. use natural tubulin variants from closely related Xenopus species to show that a...
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🔭 Are you looking for a #PhD project in infectious disease research or #immunology? Do you want to be part of an excellent research environment? 👉 The 2025 call of the IMPRS-IDI graduate school is now open with 7 PhD projects in Berlin: https://t.co/debsq6RGX0
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It was a fantastic Grand Opening Symposium at the Max-Planck-Zentrum für Physik und Medizin! 🤩 Many thanks to all the speakers for their inspiring and motivational talks over the last two days! Now we're looking forward to the official opening ceremony of the #MPZPM tomorrow!
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Congrats @GuckLab 🍾 @VasilyZaburdaev 🍾@SandoghdarLab 🍾 on the new Max-Planck-Zentrum für Physik und Medizin and a great Grand Opening Symposium! Science will be fun here! 🤩
It was a fantastic Grand Opening Symposium at the Max-Planck-Zentrum für Physik und Medizin! 🤩 Many thanks to all the speakers for their inspiring and motivational talks over the last two days! Now we're looking forward to the official opening ceremony of the #MPZPM tomorrow!
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At the new Max-Planck-Zentrum für Physik und Medizin (#MPZPM) in Erlangen, five Core Groups will conduct research to meet the most urgent medical challenges facing society. Learn more about the group ‘Cell Physics’ led by Prof Jochen Guck (@GuckLab) 👉 https://t.co/Q4b3SMAq8b
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How do #stemcells integrate information to make fate decisions? Check out our latest preprint where we find that growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to determine whether to retain or exit #pluripotency🧵👇 https://t.co/CB1vIDUFbX
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Some awesome evo/cell bio here.
How did microtubules adapt to support life across 🐸species at divergent thermal niches? Excited to share our latest work! Thanks to @elladegaulejac @luca_troman @bis_was_here @CarolynMoores1 🙌 👉 https://t.co/Mf90jneLm1
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Just another reason why #xenopus and 🐸 extracts are an awesome system to work with! Happy to have played a small part in this story 🤓 Congratulations to the whole team!! 🎉 🐸🌡️🔬
How did microtubules adapt to support life across 🐸species at divergent thermal niches? Excited to share our latest work! Thanks to @elladegaulejac @luca_troman @bis_was_here @CarolynMoores1 🙌 👉 https://t.co/Mf90jneLm1
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How did microtubules adapt to support life across 🐸species at divergent thermal niches? Excited to share our latest work! Thanks to @elladegaulejac @luca_troman @bis_was_here @CarolynMoores1 🙌 👉 https://t.co/Mf90jneLm1
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Part 2 of my postdoc work is out! We show that the ploidy-to-cell size ratio is a highly conserved, “intrinsic” determinant of cell physiology. Check out the paper for more insight into how and why. Link - https://t.co/xYcCOzXcn0 Free PDF – https://t.co/EawctsG3zn Also, a fun🧵!
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Mike Lanz's latest paper from our group on what happens when cells get too big just came out in NSMB. Read all about it at the link below. Diluting the genome produces a response similar to limiting an essential nutrient
nature.com
Nature Structural & Molecular Biology - Here the authors establish that ploidy-to-cell size ratio is a highly conserved determinant of proteome composition. In both mammals and yeast, they find...
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… the nucleus is not as dense as the cytoplasm - true for all eukaryotic cells - and the ratio is always 0.8. Go figure... @MPI_Light @MPZ_PhysMed
https://t.co/IJ45J49BQd
biorxiv.org
The packing and confinement of macromolecules in the cytoplasm and nucleoplasm has profound implications for cellular biochemistry. How intracellular density distributions vary and affect cellular...
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Review with @moofaca on the technique that has led to one of the most surprising discoveries in bio photonics, biophysics, and maybe even cell biology in recent years… https://t.co/w4T1usnLC3
nature.com
Nature Reviews Methods Primers - Holotomography is a 3D, label-free optical imaging method for visualizing living tissues and cells. In this Primer, Kim et al. discuss the implementation of...
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