Sue Tsai
@SueYTsai1
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Assistant Prof at the University of Alberta, diabetes/immunology researcher
Joined June 2020
Insulin signaling in microglia: A metabolic switch controlling neuroinflammation and amyloid pathology in Alzheimer’s disease https://t.co/d80R4amhQF
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The source of dietary fat influences anti-tumour immunity in obese mice https://t.co/omcNtkQW3J
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Mitochondrial respiration is necessary for CD8+ T cell proliferation and cell fate @NatImmunol
https://t.co/RCLCvpvnDA
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We show new ideas that lung and vagal nerves could be harnessed to prevent, improve or maybe reverse pulmonary fibrosis. @ActionPFcharity @Breathingmatter @PFTrust @IpfRm @pfforg @KevinJTraceyMD
https://t.co/jD6y5F4HNu
https://t.co/UFtlYufcSC
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I was invited to yet another internal committee today, since I contribute to “diversity”. I will not discuss how marginalized this made me feel. However, I will say that equity will not be established simply by having minority representation. It is the weight our voices carry.
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Faculty position and research chair in Immunology - applications closing soon!
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A fun process to jump into a new topic. By integrating phosphorylation regulome, iMetAct can better predict metabolic preference. Stay tuned for the next step about how we can integrate this with machine learning! @Ludwig_Cancer @CancerResearch
iMetAct: An integrated systematic inference of metabolic activity for dissecting tumor metabolic preference and tumor-immune microenvironment
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Unconventionally primed type 1 Tfh are required for long-lived IgA plasma cell development following mucosal viral infection https://t.co/TtBRQJuW5F
@JenGommerman
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Mitochondrial swap from cancer to immune cells is a functional poison pill that thwarts anti-tumor defenses https://t.co/77gBnCtGqu
@NatureNV @BrestoffLab
https://t.co/PqRtPAdGjW
https://t.co/2JY6nEtkXt
@Nature
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New paper alert📢! https://t.co/HWlHmDbFZr (@CellCellPress) - How does immune responses to solid tumors vary by age and tumor characteristics in children?! 🧵1/8
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A bit of chaotic fun in class designing and playing a tile laying survival game to model viral host immune interactions. Thank you @Offey4 💗 for mentorship and letting me experiment with teaching, and the awesome creative students 🎲🃏🧩
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Happy to announce our collaboration with @Tcellogic on metabolic features of exhausted T cells is now out in @ScienceMagazine. TL;DR they can't use acetate to fuel their function. Great work by Shixin Ma and Mike Dahabieh.
science.org
Exhausted T cells (TEX) in cancer and chronic viral infections undergo metabolic and epigenetic remodeling, impairing their protective capabilities. However, the impact of nutrient metabolism on...
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Online now: Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling
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Correction: drive to Banff can take 4hrs +/- Stdev. The mountains make you forget how long it takes; having kiddos next to you, on the other hand, exerts the opposite effects 🤣
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Our favorite sessions were the vigorous debates that help us learn from past data.
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Important milestones for the lab include Erin’s first international talk and the insightful feedback we got
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