Cell Reports
@CellReports
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Cell Reports is an open-access journal at Cell Press, publishing weekly. Tweets by Cell Reports editors.
Cambridge, MA, USA
Joined July 2011
Join the global mitochondrial community! 🌍 Submit your abstract to Cell Symposia: Multifaceted mitochondria and connect with researchers shaping the future of mitochondrial biology. 📅 Deadline: Feb 13, 2026 @CellSymposia #CSMito2026 #Mitochondria 👉 https://t.co/NIpqLKI4aQ
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Post-translational switch of DHCR24 acetylation sustains sterol synthesis and promotes HCC via the 7-ketocholesterol/p62 axis
cell.com
Zhou et al. identify DHCR24 acetylation at Lys254 as a key metabolic switch in hepatocellular carcinoma. This modification stabilizes DHCR24, enhances cholesterol synthesis, and promotes 7-ketochol...
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Quiescent ILC1 cells confer protection against MCMV infection during undernutrition
cell.com
Tatematsu et al. show that, under caloric restriction, hepatic ILC1 cells preferentially survive by adopting an mTORC1-dependent quiescent state with enhanced glucose uptake and oxidative phosphory...
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Sec61 translocon inhibitor flavitransin blocks selectively dengue virus polyprotein insertion in the ER with pan-orthoflavivirus antiviral potency
cell.com
Verhaegen et al. demonstrate that Sec61 inhibitor flavitransin selectively targets translocon insertion and ER membrane integration of the first, N-terminal transmembrane domain of the dengue virus...
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SRM1 phosphorylation coordinates plant immunity and growth in Arabidopsis
cell.com
Liu et al. demonstrate that the MYB transcription factor SRM1 promotes plant growth by activating PORA expression and enhances plant disease resistance by triggering DFR and EDS1 expression. SRM1...
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Join our Editor-in-chief Shawnna Buttery at @KeystoneSymp's, Membrane Dynamics, Repair and Disease. The short talk abstract and early registration deadline is today! Register for in-person, on-demand, or livestream access: https://t.co/0LNk8r8w5N
#KSMembrane26
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Purmorphamine exerts anti-obesity effects by enhancing secretin-activated brown fat thermogenesis
cell.com
Zhang et al. show that purmorphamine reduces body weight in diet-induced obese mice by potentiating secretin-activated thermogenesis in brown adipose tissue. The compound acts synergistically with...
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Selective decoupling of IgG1 binding to viral Fc receptors restores antibody-mediated NK cell activation against HCMV
cell.com
Antibodies targeting human cytomegalovirus (HCMV) are undermined by viral immune evasion strategies, including capture of the Fc. Qerqez et al. engineer human Fc variants with markedly reduced...
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Interleukin-1/Toll-like receptor signaling potentiates macrophage olfactory receptor 2-driven atherosclerosis
cell.com
Zhang et al. demonstrate that IL-1R1/TLR signaling enhances atherosclerosis by disrupting β-arrestin-2 (βarr2)-mediated OR6A2 internalization in macrophages. This shift, driven by βarr2K295 deSUMOy...
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DROSHA, DICER, and damage-induced long ncRNA control BMI1-dependent transcriptional repression at DNA double-strand break
cell.com
Genes near DNA double-strand breaks are silenced through a BMI1-dependent mechanism, while transcription of damage-induced lncRNAs (dilncRNAs), processed by DROSHA and DICER, occurs at break sites....
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How does inflammation shape aging? Find out from Vishwa Deep Dixit (@YaleMed) this October at @CellSymposia #CSAging2026. Submit your abstract by June 5 for a chance to join the program. https://t.co/iXarCB6u8j
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Cadherin-1-mediated communication at the leader-follower boundary controls mouse breast tumor organoid collective migration
cell.com
Morikis et al. highlight the importance of communication between breast tumor leader cells and follower cells during directional collective migration. Differential roles for cadherin-1 in followers,...
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Multi-site phosphorylation of a transcription factor orchestrates imidacloprid resistance in whitefly
cell.com
Liu et al. show that upregulation of p38 within the MAPK pathway enhances phosphorylation of Eagle at Ser363, while downregulation of PKA_C1 in the PKA pathway reduces phosphorylation of Eagle at...
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NEMO recruitment at single cytokine-receptor complexes shows quantized dynamics independent of ligand affinity
cell.com
Kim et al. leverage natural variation in IL-1β affinity across species to show that while ligand affinity sets activation thresholds, each IL-1 receptor signaling complex outputs a fixed, quantized...
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Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy
cell.com
Atakkatan et al. identify a distinct subset of C3+IL-33+ adventitial fibroblasts (AFs) that drives allergic inflammation by maintaining ILC2 responses. In turn, ILC2-derived IL-13 supports AF...
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Phosphorylation of MAP18 by MPK6 orchestrates microtubule reorganization in Arabidopsis during adaptation to salt stress
cell.com
MPK6 phosphorylates MAP18 to temporally coordinate microtubule disassembly-reassembly, thereby modulating root growth under salt stress.
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SLC44A1 deficiency impedes myelin development in the central nervous system
cell.com
Chen et al. show that oligodendrocyte-enriched SLC44A1 is essential for CNS myelination by supporting choline metabolism and phosphatidylcholine synthesis. Its loss impairs oligodendrocyte maturation...
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Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum
cell.com
Brill-Weil et al. show that axonal GABAA receptors regulate excitatory nicotinic input onto the axons of dopaminergic neurons. This regulation alters integration of the subthreshold nicotinic input...
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FoxP3 forms a head-to-head dimer in vivo and stabilizes its multimerization on adjacent microsatellites
cell.com
The transcription factor FoxP3 binds DNA through two modes: multimerization on TnG repeats to stabilize chromatin loops and head-to-head dimerization on inverted forkhead motifs. Pull-down sequencing...
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CD8+MT+ effector T cells from enlarged tumor-draining lymph nodes enhanced anti-tumor immunity and improved prognosis in colorectal cancer
cell.com
Jiang et al. performed single-cell and bulk RNA-seq on tumor-draining lymph nodes from patients with CRC, revealing enlarged, non-metastatic TDLN-enriched CD8+MT+ effector T cells with a stress-ada...
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