HoLab
@PCHo_Lab
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Scientist grew up in TAIWAN, studied in USA and work in SWISS. Love immunology, cancer and metabolism.
Lausanne, Switzerland
Joined May 2016
What a amazing 2-photon image from my superb student @Stef_Vil.
The May 2025 edition of the Ludwig Link is here! Catch up on the latest from Ludwig researchers, including awards, new leadership and a gallery of beautiful (and fascinating) micrographs. Check it out online here or download the PDF
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A mist read for liver immunologists!.
1/ 🚨 Hot off the press in @NatImmunol: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. 🧵(1/11).2/
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RT @PetrovaLab: 🚨 Still a few days left to apply!. Our department is looking to host a junior researcher aiming to apply for Ambizione, SNS….
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Having a great lunch with Alain Fischer, Phil Greenberg, Yu-Huan Tsai and my formal student and future postdoc in Taipei! Go FISS and immunology!
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RT @LabWaggoner: IFN-γ chimeric autoantibody receptor T cells broadly deplete B cells autoreactive against interferon-γ..
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Second paper in a day🫶 Checking out the work of Jhan-Jie Peng, a terrific co-mentored student. CAR T cells against autoantibody producing B cells published in @SciImmunology ! Thanks for the supports from @Ludwig_Cancer @CancerResearch @OncoUNILCHUV .
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Check out our new review with my amazing postdoc and formal trainee. A new topic and direction! #tumorimmunology #lymphnode Thanks the support from @Ludwig_Cancer @CancerResearch @OncoUNILCHUV
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Having a great time in Chicago for AACR 2025. Looking forward to share with everyone another new direction/work we explored in 10 days✌️
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It is a great journey from bench to bedside! It is also a fun process to collaborate with my formal trainees, Chin-Hsien and Sheue-Fen. @OncoUNILCHUV @Ludwig_Cancer @CancerResearch.
Online now concurrent with the #AACR25 Major Symposium on #Immunometabolism by session speaker .@PCHo_Lab: PLT012, a Humanized CD36-Blocking Antibody, Is Effective for Unleashing Anti-Tumor Immunity against Liver Cancer and Liver Metastasis
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Joining my talk on Monday in AACR. I gonna present our journey from bench to bedside. Paper will be published simultaneously during my talk. We also just got pre-IND feedback! Let’s help cancer patients with more interventions!!! @Ludwig_Cancer @CancerResearch @OncoUNILCHUV.
The AACR Annual Meeting begins today, and we’ve compiled a list of the presentations and posters by Ludwig researchers this year. Consider these excellent additions to your itinerary! #AACR25
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.@_AnaBelenAg & @PCHo_Lab review how aging& diet influence metabolic reprogramming of the tumor–immune microenvironment, contributing to cancer progression & immune evasion as well as strategies to restore antitumor immunity by targeting metabolic pathways
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RT @JExpMed: .@_AnaBelenAg & @PCHo_Lab review how aging& diet influence metabolic reprogramming of the tumor–immune microenvironment, contr….
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RT @PetrovaLab: 📢 Our department is looking to host a junior research group!.We welcome expressions of interest from cancer researchers aim….
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RT @CellReports: iMetAct: An integrated systematic inference of metabolic activity for dissecting tumor metabolic preference and tumor-immu….
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Congrats!!!! Joe is going to give a distinguished seminar at our institute in June. It gonna be exciting!.
Proud to share our group latest paper in Nature. "Spatial immune scoring system predicts hepatocellular carcinoma recurrence.".A game-changer for early-stage HCC management - high risk patients benefited from Immunotherapy - Dawn of Spatial Medicine?. Our.
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A fun process to jump into a new topic. By integrating phosphorylation regulome, iMetAct can better predict metabolic preference. Stay tuned for the next step about how we can integrate this with machine learning! @Ludwig_Cancer @CancerResearch.
iMetAct: An integrated systematic inference of metabolic activity for dissecting tumor metabolic preference and tumor-immune microenvironment
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It is a great journey to start from bench to bedside with my terrific collaborator-Huang-Yu. Thanks for @NatMetabolism and Ruoning for highlight our work. @Ludwig_Cancer @CancerResearch @snsf_ch.
Metabolic immunotherapy: L-Asparaginase enhances the anti-tumor T cell response with clinical benefits when combined with pembrolizumab.@NatMetabolism
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RT @SWculek: Looking for a #PhDposition? My lab & my colleagues @IRBBarcelona are recruiting! You want to study how dendritic cells and #ma….
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