David Kaplan
@KaplanLab_Tufts
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Department of Biomedical Engineering, Tufts University, Editor-in-Chief @ACSBiomaterials Silk, Tissue Engineering, Cellular Agriculture, Account run by students
Medford, Massachusetts
Joined June 2017
New paper! Remember this: https://t.co/8T7QBUlt2w showing massive nerve growth following zolmitriptan application in frog model? Well, now here it is in mammals! https://t.co/cWmE9X2WwE "Sustained Serotonergic Stimulation Platform for Peripheral Axonal Regeneration" @TuftsBME
nature.com
npj Regenerative Medicine - A migraine drug that modulates neurotransmitter signaling can boost the neural connections of eyes grafted onto tadpoles to enhance vision. Michael Levin and colleagues...
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Check out our new collaborative article on 'Sustained Serotonergic Stimulation Platform for Peripheral Axonal Regeneration' published in the Journal of Hand Surgery. @TuftsBME @TuftsEngineer @jugalsahoo @drmichaellevin
https://t.co/4FTTofjj9N
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New research article led by Udathari on 'Temporary silk nanocoatings preserve immune cell functions and protection against biochemical and mechanical stressors' published in Biomaterials. Check out- https://t.co/kLZk072GwG
@TuftsEngineer @TuftsBME
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New research article led by Yushu on 'Biodegradable and electroactive cryogel microspheres for neurovascularized bone regeneration' published in Matter @CellPressNews @TuftsEngineer @TuftsBME Check out: https://t.co/2zNtRSuJL3
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Check out Sanjana's latest paper on 'Fluorinated Hydrophobic Silk as Platelet Compatible Coatings for Platelet Conservation and Storage Applications'- Gopalakrishnan - Advanced Functional Materials - @TuftsEngineer #NonStickSilk
https://t.co/lCfXTy8dwL
advanced.onlinelibrary.wiley.com
The supply and storage of platelets is challenging due to the high propensity of platelets to adhere to and activate when exposed to foreign surfaces, temperature, and pH. Furthermore, the storage...
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check out @logandmorton Logan's latest paper in collaboration with @CotruvoLab published in @ACSBiomaterials on 'Mechanically and Chemically Robust Lanmodulin-Functionalized Silk Sponges for Rare Earth Element Sequestration' | @jugalsahoo @TuftsEngineer
https://t.co/5do0Yr7AdF
pubs.acs.org
The extraction of rare-earth elements (REEs) from low-grade sources like electronic waste (E-waste) could supplement current unsustainable mining practices. REEs are crucial for various industries,...
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Out in @NatureRevMat, we chart the biomaterials toolkit for future foods: polysaccharides, plant & microbial proteins, lignin, polyesters, then show how AI-driven multiscale modeling can de-risk scale-up, tune texture + nutrition, and hit safety & LCA targets in cellular-ag and
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Recent paper from the group led by Olivia is now out- Functional Nanoparticle‐Enhanced Silk Hydrogels for Tissue Engineering Biomaterials - Foster - 2025 - Journal of Biomedical Materials Research Part A - Wiley Online Library https://t.co/lLwzNXl4sV
@SunnyShaidani @Chjacobus23
onlinelibrary.wiley.com
Hydrogels prepared from natural polymers, such as silk fibroin, are useful in the field of tissue engineering due to their biocompatibility, biodegradability, and biological performance. However,...
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Growing new tissues and organs in the lab holds incredible promise, but seeing what's happening inside these complex structures remains a major hurdle. Traditional optical imaging can’t penetrate the thick, opaque scaffolds often used in tissue engineering. To address this,
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Check out our recent review on 'Biomaterials in cellular agriculture and plant-based foods for the future' led by Edward, just published in @NatRevMater @ProfBuehlerMIT #FutureFoods #CellAg #Sustainability
https://t.co/fzeEnv7kbt
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Check out the latest paper from the group led by Sophia on 'Establishment & characterization of a non-adherent insect cell line for cultivated meat' published in @SciReports @TuftsEngineer @TuftsBME
https://t.co/ObdR1WoXQm
nature.com
Scientific Reports - Establishment & characterization of a non-adherent insect cell line for cultivated meat
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First PhD defense in 2025- Sunny successfully defended her PhD thesis yesterday about her work in silk nanoparticles and protein coronas. Amazing work and job well done. Full steam ahead. @SunnyShaidani
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This pre-print is now published! Thanks to the @tuftscellag industrial consortium for supporting this work! @TuftsEngineer @TuftsUniversity @KaplanLab_Tufts @GoodFoodInst See it here:
🆕New pre-print🆕! Our first foray into 🥩cultivated meat🍖 with @KaplanLab_Tufts Kyong Lee @tuftscellag! We report that microbial lysates can be used as serum alternatives for in vitro animal cell proliferation. https://t.co/5aecBKsDs6
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Head injury may raise the risk of neurodegenerative disease by awakening a dormant virus @scisignal @KaplanLab_Tufts
https://t.co/ELrG2yhYFu
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A new study connects herpes simplex virus and neuroinflammation from #TraumaticBrainInjury to #AlzheimersDisease and finds that blocking the cytokine #IL1B prevents amyloid accumulation in latently infected cells. @KaplanLab_Tufts @TuftsBME
https://t.co/IJf7IT2UzD
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@gpgrazioli @Kariem_Ezzat @PAULJLAMONT @SuzanneESchind1 @ProfRobHoward @LonSchneiderMD @LogarithmicDis @MemoryDoc @AlbertoEspay @nvillain_alz @seb_walsh @EWidera @LTCShop @MadhavThambiset @RenegadeSynapse @dr_shibley @PhilAlz @_michael_scholl @StefanoSensi14 @Gill_Livingston @DrTFromKC @jasonkarlawish @JamesRuFletcher @AdamMBrickman @ManlyEpic @SFAckley @howard_gleckman @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @EmmyBetz @DrJoRyan @MaggieAime @OskarHansson9 @DavidJonesBrain @PTenigma @Ayisha_Sharma97 @EMA_News @NICEComms @TGAgovau @CDA_AMC Using lab-grown human mini-brains, scientists find links between head trauma, herpes, and Alzheimer’s: @KaplanLab_Tufts et al research suggests concussions could awaken latent infections in the brain and lead to dementia https://t.co/MnbGTL19CJ via @MeganMolteni
statnews.com
Research published Tuesday is the first to connect the dots between a common herpes virus, head injury, and Alzheimer's.
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Check out our recent paper in Science Signaling @scisignal led by Dana on 'Repetitive injury induces phenotypes associated with Alzheimer’s disease by reactivating HSV-1 in a human brain tissue model | Science Signaling @TuftsBME @TuftsEngineer
https://t.co/bOMraZH281
science.org
Head injury may raise the risk of neurodegenerative disease by awakening a dormant virus.
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Check out our latest paper led by Yushu published in @NatureComms on silk based living bioplastics via plasticizer-assisted thermal molding of silk congratulations Yushu. #Livingbiomaterials
@KaplanLab_Tufts
@TuftsBME
https://t.co/aoPS2VrVyu
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We celebrated the success of all our group members in 2024 at our group holiday party yesterday evening !! We had a lot of fun with great food, a Yankee gift swap, and a fun award for lab superlatives. Happy holidays everyone !! @TuftsUniversity @TuftsEngineer @TuftsBME
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Selective Biofilm Inhibition through Mucin-Inspired Engineering of Silk Glycopolymers | Journal of the American Chemical Society @MITdeptofBE @MIT @TuftsEngineer @TuftsUniversity #Biofilm #Inhibition #Mucin #Emgineering #Silk #Glycopolymers
pubs.acs.org
Mucins are key components of innate immune defense and possess remarkable abilities to manage pathogenic microbes while supporting beneficial ones and maintaining microbial homeostasis at mucosal...
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