Nair @Nair Lab
@nair_lab
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#SynBio #ProteinEngineering #MetabolicEngineering #MicrobiomeEngineering lab @TuftsUniversity @TuftsEngineer @[email protected] @nair-lab.bsky.social
Medford, MA
Joined June 2018
🆕New pre-print🆕! Our first foray into 🥩cultivated meat🍖 with @KaplanLab_Tufts Kyong Lee @tuftscellag! We report that microbial lysates can be used as serum alternatives for in vitro animal cell proliferation. https://t.co/5aecBKsDs6
biorxiv.org
Cultivated meat, the process of generating meat in vitro without sacrificing animals, is a promising alternative to the traditional practice of livestock agriculture. However, the success of this...
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This pre-print is now published! Thanks to the @tuftscellag industrial consortium for supporting this work! @TuftsEngineer @TuftsUniversity @KaplanLab_Tufts @GoodFoodInst See it here:
🆕New pre-print🆕! Our first foray into 🥩cultivated meat🍖 with @KaplanLab_Tufts Kyong Lee @tuftscellag! We report that microbial lysates can be used as serum alternatives for in vitro animal cell proliferation. https://t.co/5aecBKsDs6
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🚨 We’re Hiring! 🚨 Join the Molinari Lab @UMD_BioE as a Postdoctoral Associate or Staff Scientist and help shape the future of engineered living materials! 💡🔬 📅 Apply today by sending your CV and cover letter at saramol@umd.edu #syntheticbiology #ELMs
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Advancing protein display on bacterial spores through an extensive survey of coat components https://t.co/l43BzIoxCE
#biorxiv_synbio
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Finally, we show that engineered spores can be used to degrade plastic PET films. #plasticdegradation
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We compare coat proteins for surface availability and protection from inactivating agents (e.g., heat, protease), and their effect on sporulation efficiency. We also assess how different coat proteins can be co-utilized to increase display levels.
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Allelic tagging allows us to examine the activation timing and strength of promoters associated with spore coat structural proteins.
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In addition, this work investigates scarless allelic tagging of spore coat proteins using genome editing by co-transformation, analyzing factors affecting genome editing by congression.
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🚨🆕New manuscript🆕🚨from the lab! Started by @TrevorBNicks & completed by ToddChappell. This work assesses the utility of >30 spore coat proteins for #surfacedisplay - almost 3x currently described! We found that SscA is a great carrier not used before‼️ https://t.co/KpYZ2eRWV1
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#ICME #microbiomeEngineering conference is ongoing now! Fantastic talks so far and excellent audience participation! @TuftsUniversity @TuftsEngineer
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@SarahLebeer shares what she’ll be speaking about in her #ICME2024 keynote and talks about new technologies that have influenced her research. https://t.co/H8i5RkNSb7
#microbiome #labonchip #superbugs #antibioticresistance #synbio #bioinformatics
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There's still time to register for #ICME #MicrobiomeEngineering next week at @TuftsUniversity! Fellowships are still available to cover registration fees for trainees and asst. profs.! https://t.co/Uq5OfkYaMn
aiche.org
This conference brings together scientists across the quickly growing field of microbiome engineering. The conference integrates synthetic biology, systems biology, microbial ecology, and bioinform...
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Less than one week until the 7th International Conference on Microbiome Engineering, an event that integrates synthetic biology, systems biology, microbial ecology, and bioinformatics across a range of application spaces. Learn more and register at https://t.co/5GspTr9OsA.
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Microbial lysates as low-cost serum replacements in cellular agriculture media formulation https://t.co/NwYvgBi8BH
#biorxiv_bioE
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With a distinguished career at the intersection of veterinary medicine and biotechnology, Dr. Arvind Kumar specializes in pioneering technologies that aim to transform livestock health and sustainability through microbiome research. Register here: https://t.co/rab8ptF1Ha
#ICME24
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The work was led by post-doc Damayanti Chakravarty (Nair) & @DolginJames (Kaplan) w/ support from Pomai Yamaguchi (Lee) & many others from the Nair & Kaplan groups.
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We found that both, protein + metabolites, in VN lysate are needed to support fast growth. The cells were less stressed on VN lysate when compared to other serum alternatives and could be differentiated after several passages.
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We found that different cell lines are compatible with different microbial lysates. We were able to adapt bovine satellite cells for long-term growth on Vibrio natriegens lysate. After adaptation, their growth rate on VN lysate was similar to that on serum.
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