David Jones
@DavidJonesBrain
Followers
2K
Following
3K
Media
402
Statuses
3K
Neuroscience, Cognitive and Behavioral Neurology, Complex Systems, AI, Alzheimer's and Multimodal Neuroimaging, content personal opinion https://t.co/6QLYHTNahe
Minnesota, USA
Joined November 2015
I have started accumulating prerecorded video lectures, and some folks may find them useful so I am going to start posting them on this channel. First 2: Should amyloid be targeted in Alzheimer's disease? Progressive dysexecutive syndrome due to AD https://t.co/DtQL8uq3DW
youtube.com
I am a practicing Neurologist that specializes in conditions that impact perception, cognition, and behavior. I give invited lectures and prepare educational material about Alzheimer's disease (AD)...
6
16
116
New discovery: A brain wave sweeps across the cortex like radar, scanning a mental image in working memory to read it out.
When spotting what’s changed from one scene to the next, performance will depend on a low-frequency “theta” brain wave that scans the mental image, a new MIT study in @NeuroCellPress shows https://t.co/kMQb7nRZaz
#neuroscience #cognition @ScienceMIT @mitbrainandcog
1
13
119
I said it before and I'll say it again: Cognition is rhythmic Contents of visual predictions oscillate at alpha frequencies https://t.co/F5725iDQIJ
#neuroscience
jneurosci.org
Predictions of future events have a major impact on how we process sensory signals. However, it remains unclear how the brain keeps predictions online in anticipation of future inputs. Here, we...
7
21
124
🚨New in Lancet Neurology: Autopsy study of aducanumab in #Alzheimer’s shows superficial cortical Aβ cleared, but deeper persists. ARIA showed inflammation+ microinfarcts in leptomeningeal/penetrating vessels. Some path is PET-invisible. @DrNeuroChic
https://t.co/gAStfXlsTX...
3
31
64
Nature Rate and noise in human amygdala drive increased exploration in aversive learning https://t.co/GbAVgXRG8q
nature.com
Nature - Human exploration is driven by two distinct neural mechanisms, a valence-independent rate signal and a valence-dependent global noise signal.
1
11
99
Trends in Cognitive Sciences Testing circuit-level theories of consciousness in humans https://t.co/8Ax6M0A2cZ
4
50
185
Sequential predictive learning is a unifying theory for hippocampal representation and replay https://t.co/9WRGROvR37
biorxiv.org
The mammalian hippocampus contains a cognitive map that represents an animal’s position in the environment [1][1] and generates offline “replay” [2][2],[3][3] for the purposes of recall [4][4],...
0
10
54
I can not emphasize this enough. Senior people need to make space for new innovation
10
11
98
Human auditory cortex integrates information in speech across absolute time (e.g., 200 ms), not phonemes, syllables, words, or any other time-varying speech structure: https://t.co/63T8qdQkUH
4
19
57
New EEG work shows a neat dissociation in attentional rhythms. When we sustain attention on space or features, alpha (8–12 Hz) dominates. But when attention must explore or reorient, especially across spatial locations, theta (4–7 Hz) emerges. Post-stimulus theta rises on
Alpha for sustained attention, theta is the wanderer. Theta-rhythmic attentional exploration of space https://t.co/EYvIRkykev
#neuroscience
1
1
15
Surprising but important and I’ll change my mind on this subject
1
1
6
1
2
22
The hippocampus is one of the most studied brain areas because of its major role in fundamental brain functions including learning, memory, and spatial navigation. In a new #ScienceReview, researchers focus on the role of overlooked areas and circuits within the hippocampus.
6
173
751
NPH is common and reversible cause of dementia symptoms. It’s obviously cost effective for health systems to prioritize proper diagnosis and treatment of all patients presenting with cognitive decline.
neurology.org
Background and ObjectivesIdiopathic normal pressure hydrocephalus (iNPH) is an underdiagnosed but potentially treatable condition in older adults. Population-based data on incidence and progression...
0
2
4
Johansson et al. leverage longitudinal clinical and task-based fMRI data to show that progression of bradykinesia in PD relates more strongly to changes in compensatory mechanisms in the dorsal premotor cortex, than to advancing nigrostriatal dysfunction. https://t.co/ggKvwMmxbH
0
3
23
Do inhibitory interneurons encode information or just keep the rhythm? https://t.co/2aSqdbywIb
science.org
Inhibitory interneurons may help encode the brain’s internal representation of space
0
23
90
This one made me smile. September cover of @Brain1878 depicts Hume and Sartre in animated conversation, accompanying a new essay on mental imagery by Margherita Arcangeli and @PaoloBartolome0
https://t.co/IM2zhHF3tj
1
9
43
Brain-wide organization of intrinsic timescales at single-neuron resolution https://t.co/AZNxen4M6i
biorxiv.org
Variations in intrinsic neural timescales across the mammalian forebrain reflect the anatomical structure and functional specialization of brain areas and individual neurons. Yet, the organization of...
2
14
60
Mayo Clinic experts, with partners, developed an individualized ALS therapy for Dr. Rakesh Parekh — the first person in the world to receive a treatment targeting a CHCHD10 mutation. A bold step in precision medicine — halting disease progression and offering new hope.
6
6
35
Neurology Podcast: Dr. Trey Bateman and Dr. David T. Jones discuss how the StateViewer system leverages FDG-PET imaging and machine learning to improve diagnostic accuracy for #AlzheimerDisease and related disorders. Listen now: https://t.co/rgAJyTgr2j
#NeuroTwitter
4
6
14