Severe head impacts can cause deadly internal bleeding, and the lack of reliable risk estimation limits early intervention. Engineers developed a new computational model to predict bridging vein rupture and simulate the growth of acute subdural hematomas using the Global Human

Ensuring prostate tumors are fully treated without harming surrounding tissue often depends on a clinician’s hands-on experience during cryotherapy. To improve procedural consistency, researchers developed Image-guided Adaptive Cryotherapy (ImAC), an MRI-based system that

When cholesterol regulation fails, the brain’s protective barrier may weaken, potentially accelerating neurological disease. Using human stem cell–derived brain endothelial cells, researchers tested how chemical cholesterol depletion affects blood–brain barrier integrity by

High-precision tracking of hip motion remains limited by the radiation exposure required for current imaging methods. Researchers took aim at this by evaluating whether MRI-derived synthetic computed tomography (sCT) could replace traditional CT scans to provide the bone surface

Predicting how concussion affects an athlete over time remains one of the biggest ongoing gaps in sports medicine, limiting the ability to deliver truly personalized monitoring and care. Researchers analyzed data from more than 3,200 collegiate athletes in the CARE Consortium

Improving astronaut safety depends on understanding how extreme landing forces can cause life-threatening lung injuries. To address this risk, researchers combined high-impact landing tests using a crash-test mannequin with computer simulations to understand how landing forces

Seatbelts save lives – but to protect everyone consistently, we need to know how they load the body in high-speed crashes, especially for women. In controlled sled tests using female postmortem human surrogates, researchers examined how lap belt forces contribute to fractures of

Accurately measuring the forces athletes’ heads experience during impacts remains a critical challenge for protecting players from concussion and other brain injuries. In pursuit of more reliable field measurements, researchers developed and validated an approach using

Stepping over uneven terrain challenges the body’s ability to stay balanced while keeping forward motion efficient. Researchers analyzed gait biomechanics in 18 participants negotiating holes in a walking surface, tracking joint kinematics, muscle activity, center-of-mass

Concerns about long-term brain health in football continue to drive efforts to identify practical ways to make heading safer. In the latest example of that, engineers tested whether lowering ball inflation pressure reduces head-impact kinematics during heading using an

Large bone defects often fail to heal fully because current grafts struggle to regenerate tissue uniformly across the entire injury site. To overcome this limitation, researchers developed a biphasic scaffold that pairs a mechanically robust, porous outer structure with an

Concerns about long-term implant durability continue to drive efforts to better understand why silicone breast implants sometimes fail under everyday forces. Using a Finite Element Analysis framework, researchers modeled implant shells under two clinically relevant conditions –

Facial symmetry remains difficult to restore for individuals born with microtia because current reconstructive options often fall short both aesthetically and medically. In a review, researchers discussed emerging tissue-engineering strategies designed to overcome the

One of the biggest challenges in treating solid tumors is reversing the immunosuppressive environment that helps cancer grow. Responding to this need, researchers explored whether they could locally reprogram tumor-associated macrophages – immune cells that often support tumor

Autofluorescence in plant-derived biomaterials makes it difficult for researchers to clearly visualize how cells behave and integrate with these scaffolds. Scientists evaluated whether three quenching agents – copper sulfate, ammonium chloride, and sodium borohydride – could

Regenerating damaged knee cartilage remains a major obstacle in orthopedic care, leaving many patients without durable solutions for long-term joint function. Against this backdrop, researchers outlined how advances in biomaterial design are enabling new tissue-engineered

Rotator cuff tears can quietly erode shoulder function, yet clinicians still lack clear, non-invasive markers that reveal how deeply the tendon’s mechanical integrity has been compromised. Researchers examined cadaveric supraspinatus tendons to test whether quantitative MRI

Achieving reliable whole-body movement estimates remains difficult when conventional tools assume idealized, noise-free data and offer no sense of how uncertain their outputs really are. To address this, researchers introduced AUKSMIKT, a Bayesian kinematics estimator built

Improving mobility for people with osteoarthritis (OA) depends on tools that can reliably measure how their lower limbs move during walking – without requiring expensive, time-intensive motion-capture setups. To this end, researchers developed and validated a dual-camera