J. Am. Chem. Soc.
@J_A_C_S
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Research, news, and information from the Journal of the American Chemical Society.
Washington, DC
Joined December 2008
Rapid-response DNA sensors developed at Université de Montréal and showcased in JACS could redefine blood diagnostics and pave the way for groundbreaking advances in disease treatment. Explore the research, as referenced in News Medical: https://t.co/Kg5QpL4vko
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On the cover of this week's issue: "Strong Coupling of Iridium and Boron–Carbon-Nitride Support for Enhanced Acidic Water Oxidation" Read it here 🔗 https://t.co/kTQjaPFZkf
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JoggAI Black Friday is HERE! Spin the Lucky Wheel for up to +100% credits, then upgrade during the campaign to unlock your boosted plan. Get 50% off any Annual Plan — and your Credit Boost stacks with the discount.
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The #ACS150 JACS Symposium Series: @Kor_Chem_Soc General Meeting celebrates 150 years of breakthroughs in organic, inorganic, and sustainable chemistry. 📍 Jeju Island, South Korea 📅 15 April 2026 Apply to attend this free, in-person event: https://t.co/DBmpKw1wFQ
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Intermolecular Attraction–Repulsion Forces Enable Self-Reinforcing Electrolytes for Wide-Temperature Sodium Metal Batteries | Journal of the American Chemical Society
pubs.acs.org
Developing an electrolyte system with stable performance over a wide temperature range is crucial for energy storage devices operating in extreme environments, especially achieving both simultaneou...
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Catenanes of Twin-Cavity Cages | Journal of the American Chemical Society
pubs.acs.org
Catenanes, interlocked molecular architectures, hold promise for molecular machines and catalysis, yet constructing complex topologies from multicavity cages remains challenging. Herein, we report...
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Stepwise Ligand-Exchange Strategy for the High-Yield Synthesis of Water-Soluble, Metal-Doped MAg24 Nanoclusters | Journal of the American Chemical Society
pubs.acs.org
Water-soluble gold nanoclusters (NCs) with diverse nuclearities and protecting ligands have been extensively investigated as luminescent probes for biosensing and bioimaging. In contrast, the...
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Hydrogen-Bond-Donor Coupled Electron Transfer Enabled Copper-Catalyzed Asymmetric Radical Alkynylation with a Planar Chiral Ligand | Journal of the American Chemical Society
pubs.acs.org
H-bonding noncovalent interactions can efficiently facilitate electron transfer in many biological processes and organic transformations, enabling the activation of inert chemical bonds. As a...
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Colloidal Crystals Engineered with DNA from Supramolecular Programmable Atom Equivalents with Stimuli-Responsive Cores | Journal of the American Chemical Society @CHADNANO @NUChemistry @NorthwesternU
pubs.acs.org
Oligonucleotide-functionalized nanoparticles (NPs), known as “programmable atom equivalents” (PAEs), are the primary building blocks for the field of colloidal crystal engineering with DNA. With...
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In Situ Observation of Active Surface Etching in Gold Nanoplates: Evidence for Intermediate Ligand Effects | Journal of the American Chemical Society
pubs.acs.org
We report the in situ observation of active surface etching in Au nanoplates using liquid-cell TEM. By analyzing the distinctive etching modes and in combination with our previous ex situ etching...
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Enantioselective Radical Sulfonylation of 2-Naphthols and β-Ketoamides with Sodium Sulfinates | Journal of the American Chemical Society
pubs.acs.org
Sulfones represent privileged structural motifs in pharmaceuticals and bioactive molecules. Despite advances in constructing C(sp3)–SO2 bonds via sulfonyl anions or radicals, enantiocontrol remains a...
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Thermally Stabilized Hydrogenation Dynamics in Single-Atom Alloys Enables Selective CO2 Electroreduction | Journal of the American Chemical Society
pubs.acs.org
Electrochemical CO2 reduction to single-carbon products is central to sustainable fuels and chemicals, but under industrially relevant conditions elevated temperature fundamentally alters reaction...
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Nickel(0)/Phosphine-Catalyzed Copolymerization of CO2 and Cyclohexylallene to Degradable Long-Chain Polyesters | Journal of the American Chemical Society
pubs.acs.org
Developing efficient strategies to copolymerize carbon dioxide (CO2) with unsaturated hydrocarbon monomers, such as olefins, to produce CO2-based polyesters is highly desirable but remains challeng...
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Aromatic Ketone-Mediated Two-Electron Lithiation for Rapid and Room-Temperature Regeneration of Spent LiFePO4 Cathodes | Journal of the American Chemical Society
pubs.acs.org
Addressing the growing demand for sustainable lithium-ion battery (LIBs) recycling, we present a novel aromatic ketone (AK)-mediated chemical lithiation reaction for the rapid and spontaneous...
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Light-Activated Metal-Dependent Protein Degradation: A Heterobifunctional Ruthenium(II) Photosensitizer Targeting New Delhi Metallo-β-lactamase 1 | Journal of the American Chemical Society @KingsCollegeLon @TheCrick @Jeannine__Hess
pubs.acs.org
Antimicrobial resistance (AMR) is a global health threat, yet, despite this, antibiotic drug discovery has stagnated. Most compounds entering the clinic represent already discovered classes, to which...
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Single-Atom-Layer-Induced Reversed Diffusion Pathway of Reactive Metal–Support Interaction | Journal of the American Chemical Society
pubs.acs.org
Reactive metal–support interaction (RMSI) exhibits great potential in modulating the component, configuration, and electronic structure of supported metal catalysts. While current experimental and...
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A Unified Synthetic Approach to 2-Alkyl Azetidines, Oxetanes, Thietanes and Cyclobutanes from Unactivated Alkenes | Journal of the American Chemical Society
pubs.acs.org
2-Alkyl substituted four-membered carbocycles and heterocycles are relevant motifs in pharmaceuticals and agrochemicals. However, synthetic methods to access these scaffolds mostly rely on functional...
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Rewiring the Fusion Oncoprotein EWSR1::FLI1 in Ewing Sarcoma with Bivalent Small Molecules | Journal of the American Chemical Society
pubs.acs.org
Dysregulated transcription is a defining hallmark of cancer. Recently, novel chemically induced proximity approaches have enabled the rewiring of transcriptional machinery to drive expression of...
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Decoding the Elusive Redox Properties of [FeS] Clusters in [FeFe]-Hydrogenase on a Nanostructured Electrode | Journal of the American Chemical Society
pubs.acs.org
Proton-coupled electron transfer (PCET) is essential for [FeFe]-hydrogenase to operate reversibly with high activity at a minimal overpotential. However, whether the reduction of the [4Fe4S] cluster...
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From Bits to Bonds: High-Throughput Virtual Screening of Ribonucleic Acid Nanocarriers Using a Combinatorial Approach of Machine Learning and Molecular Dynamics | Journal of the American Chemical Society
pubs.acs.org
The implementation of high-throughput methods for fuelling the design of effective nanocarriers for RNA delivery remains challenging. Traditional experimental screening is resource-intensive, while...
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Operando Analysis of Nickel Catalyst Speciation in Reductive Biaryl Synthesis Using Thin Layer Electrochemistry and a Microelectrode | Journal of the American Chemical Society @UWMadisonChem @UWMadison
pubs.acs.org
Operando insights into nickel speciation during nickel-catalyzed cross-electrophile coupling reactions could play a major role in advancing these reactions, but analytical methods capable of provid...
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