Bhattacharyya Lab
@moitrayee_lab
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science enthusiasts in Pharmacology @Yale studying molecular mechanisms of cell signaling in cancer and neurodegeneration (https://t.co/hKUrRJr3D2)
New Haven, CT
Joined February 2020
Here is a tweetorial summarizing findings from our recent paper from @YalePharm @YaleMed in @NatureNano by @GTWalker7 and @CBcellbiologist. Dream team @shalgene @Xiangyu_GigiG @MuzumdarLab @GuptaLab1! Also see the N&Vs at https://t.co/qnH21l0l2R by @KrishnanYamuna!
New content online: Oligomeric organization of membrane proteins from native membranes at nanoscale spatial and single-molecule resolution https://t.co/4VoCODdGMl
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Researchers in the Vosshall lab have discovered the first evidence of what happens when a female mosquito chooses to mate for the one and only time in her life. We spoke to @leslievosshall and @LeahHouri about their unexpected findings. See the full Q&A: https://t.co/4NODZOfc9n
rockefeller.edu
Researchers have discovered the first evidence of what happens when a female mosquito chooses to mate for the one and only time in her life.
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Super-resolution single-molecule fluorescence meets quantitative phase contrast! This powerful combo enables ~0.05 nm optical path difference detection, < 20 nm resolution, and continuous live-cell imaging with digital staining, opening new windows into molecular dynamics!🔬
A correlative quantitative phase contrast and fluorescence super-resolution microscope for imaging molecules in their cellular context
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This is a game changer
Here’s the big one: In collaboration with @Honigmann_Lab, @LabShevchenko, Björn Drobot and Martin Hof we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. https://t.co/uotVrHnbsK
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Many congratulations @JunLiuLab for this beautiful work!
Exciting findings from @JunLiuLab #postdoc @YueJianUSTC @YaleMed Architecture and activation of the Legionella Dot/Icm type IVB secretion machine #cryoEM #cryoET #Legionella
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The call just opened! https://t.co/1N2ANmLUaJ You can apply to several departments simultaneously, check out which depts better fit your profile! Here is the call for our Department of Medical Biochemistry and Biophysics https://t.co/tZiRFnNlDJ
ki.varbi.com
Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universities,
Come and join us! Start your group at Karolinska Institutet @karolinskainst! https://t.co/xN7BBHR047
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The secret to how nucleosomes shape the genome | Journal Club | PNAS
pnas.org
Nucleosomes--which are composed of histone proteins (purple) wrapped in strands of DNA (green)--appear to regulate gene activity via inherent biophysical properties.
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Excited to attend and speak at the https://t.co/4GAik1vRjO about our work on NGF receptor TrkA @YalePharm @YaleMed! Dr. Shailesh Kumar from my lab is also presenting a poster. Looking forward to hearing about cool new discoveries in the area! @GordonConf
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Check out this tour de force study by Sangwoo Park and his incredible team of collaborators. Biophysical properties of single nucleosomes are responsible for A and B compartments in cell nucleus.
"Native nucleosomes know where to go!” Our Condense-seq paper is now published in Nature! 📄 https://t.co/hNWY0rxsnk I’m deeply grateful to my PhD advisor @taekjip and our incredible collaborators @MuirLab , @binzmit , Erika Pearce, and Ben Garcia lab!!
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https://t.co/yxUQxvHO3t I am hiring a postdoctoral fellow with expertise in molecular modeling and machine learning approaches to accelerate our growing predictive formulation development pipeline. DM me to know more
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Our scientists with over 150 collaborators have released the largest functional map and wiring diagram of the brain to date – seven years in the making. Today’s 1.6 petabyte release marks a historic day for neuroscience. This moonshot milestone will further efforts towards
How does the brain work? Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵
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A big step forward for biomolecular ultrasound! 🔊 Congrats @bgheiles, @DMarescalab at @tudelft and collaborators! #gasvesicles
A new method reported in Science allows the generation of 3D ultrasound images of gene expression and 2D ultrasound images of capillary vessels. The approach enables fast, deep, and volumetric imaging of living opaque organs labeled with echogenic reporters. Learn more in this
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Thank you @Hypothesisfund and Yamuna Krishnan for this opportunity to shed “light” on membrane contact sites! Very honored to be a part of this mechanism and congratulations to my fellow awardees. Can’t wait to start this scientific adventure in my lab @YalePharm @YaleMed!
4/ With a 'molecular scalpel'🔪 to 'biopsy' membrane sites where cells/organoids make contact, Awardee @moitrayee_lab's research may reveal new insights into cellular processes & disease development (e.g. ALS). 🎉Congrats Dr. Bhattacharyya! @Yale 🙏#HFScout Yamuna Krishnan
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Thrilled to share that my work from postdoctoral research has been published in @Nature . Huge thanks to my mentor Dr. Edward Twomey, and collaborators Elisa Carrillo and Prof. Vasanthi Jayaraman. https://t.co/OjxRxSzA6C
nature.com
Nature - Physiological temperatures augment activation of glutamate receptors, which enables the structural basis of neuronal excitation to be elucidated.
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Join us in welcoming our next 2025 Pharmacology Seminar Series speaker, Susan Shao (@sshaolab). She will be presenting her work at 12 pm on Thursday, March 27th in the Brady Auditorium.
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Thrilled to share our latest work published in @CellCellPress: Turnover Atlas of Proteome and Phosphoproteome Across Mouse Tissues and Brain Regions! https://t.co/LrnmFtK24I
@Yanshen73854711 @JunminPengLab @euforna @YaleMed @YalePharm @CancerYale @HUPO #Proteomics #TeamMassSpec
cell.com
This study presents a comprehensive atlas of protein and phosphoprotein turnover across 16 mouse tissues and brain regions using advanced proteomics and isotope labeling. It reveals tissue-specific...
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Excited to share our latest work on songbirds showing dopamine guides learning of natural behavior https://t.co/ufuX4F2rRV Congrats to @JonathanKasdin Alison Duffy Nathan Nadler @pantamallion @alfairhall @neuro_kim ! @ZuckermanBrain @Columbia @GoogleDeepMind @UW
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Our new preprint is out＠bioRxiv: https://t.co/sUqL7fcfMe
@MasaAShimazoe et al. reveal that linker histone H1 acts as a liquid-like "glue" to organize chromatin in living cells. 🎉 Fantastic collab with @rcollepardo, Charlie Phillips, @janhuemar and others—huge thanks! 🙌 1/2
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Very excited to host Dr. Stephen Sligar this Thursday! Anyone doing membrane protein biophysics will immediately recognize his immense contributions in enabling reconstitution of membrane proteins in lipid nanodiscs and subsequent applications! Hope to see many of you there!
Join us in welcoming our next 2025 Pharmacology Seminar Series speaker, Stephen Sligar. He will be presenting his work at 12 pm on Thursday, February 27th in the Brady Auditorium.
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