Anish Kumar Mondal
@anish_kumar_07
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Postdoctoral fellow Biophysics and Biophysical Chemistry @BiophysicsJHMed @HopkinsMedicine @JohnsHopkins, Ph.D. @DBS_IISERM @IiserMohali
Baltimore, MD
Joined May 2011
Thrilled to share that my work from postdoctoral research has been published in @Nature . Huge thanks to my mentor Dr. Edward Twomey, and collaborators Elisa Carrillo and Prof. Vasanthi Jayaraman. https://t.co/OjxRxSzA6C
nature.com
Nature - Physiological temperatures augment activation of glutamate receptors, which enables the structural basis of neuronal excitation to be elucidated.
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Delighted to share our latest study published online now @Structure_CP, from @DBS_IISERM @IiserMohali. This is the PhD work of Mahendra @M_S_Dharmawath, in collaboration with @s_ndutta lab and @Jmondal_tifrh lab.
Online now! Cradle loop regulates β-barrel pore-formation mechanism of Vibrio cholerae cytolysin
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Thrilled to have played a small role in our new paper ‘Delta-type glutamate receptors are ligand-gated ion channels’ — now published! 🔬 Read it here:
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Honored to receive the prestigious Paul Ehrlich Research Award as part of this year's Young Investigators' Day Program at Johns Hopkins School of Medicine. Grateful for the recognition and the incredible community at Hopkins. @Hopkins_YIDP
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Thrilled to be a part of this wonderful study describing a novel TLR assembly.
Delighted to share our recent paper in PLOS Pathogens, a collaborative work with Kausik lab @KausikChatt at @DBS_IISERM @IiserMohali
https://t.co/Ze7kfUPF8c
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#Scientists have visualized how glutamate opens #AmpaReceptor channels in #Neurons, a process crucial for learning and thinking. This insight may lead to new treatments for epilepsy and intellectual disorders. @nature
https://t.co/bn4b5A5SmU
medicalxpress.com
In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the...
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Check out the research briefing on our paper for a quick overview.
nature.com
Nature - Structures of drug-free brain receptors are resolved by warming them to physiological temperatures.
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We demonstrated that AMPA receptor gating are sensitive to temperature, and using a temperature-resolved cryo-EM approach, we captured the first activated-state of an ionotropic glutamate receptor (iGluR) in the presence of only glutamate, without using any drugs.
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Exciting news !! I will be showcasing my poster tomorrow at #bps2025 ! And don’t miss my platform talk on 18th feb. !! I will be talking about my recent work glutamate gating in AMPARs. Come by for insights and discussions.
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Human TRPV4 engineering yields an ultrasound-sensitive actuator for sonogenetics | bioRxiv https://t.co/zxpCZAgFf8
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Ratan Tata ’59, B.Arch. ’62, the university’s most generous international donor and one of India's most respected business leaders and philanthropists, passed Oct. 9. We will remember his legacy of transformative giving to Cornell. https://t.co/0v0zYb6aGl
news.cornell.edu
Ratan N. Tata ’59, B. Arch. ’62, one of India’s most influential and respected business leaders and philanthropists, and a former Cornell trustee who became the university’s largest international...
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An announcement: The O'Brien lab is hiring!! If you're interested in GPCR structural biology, dynamics, and/or drug discovery, see posting for postdoc position(s) here ( https://t.co/unDkTl5eQ3) and (NEW!) lab website ( https://t.co/7JDjP63Gku) for more. Please share this widely!!
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Happy to share our recent work accepted for publication in the Biochemical Journal. @Biochem_Journal @DBS_IISERM
@IiserMohali with Kusum Lata and @GAnderluh
https://t.co/j5OJ7GBg7p
portlandpress.com
Cholesterol-dependent cytolysins (CDCs) are the distinct class of β-barrel pore-forming toxins (β-PFTs) that attack eukaryotic cell membranes, and form large, oligomeric, transmembrane β-barrel...
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Researchers @CeNSEatIISc report in @Nature a brain-inspired platform that can store & process data in 16500 states, a huge leap over digital computers limited to 2 states. It can potentially bring complex AI tasks to personal devices. https://t.co/SHSDd9TnU4
#IIScresearch
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Excited to share that our preprint is now available! Check out our latest findings @biorxivpreprint.
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CryoET of β-amyloid and tau within postmortem Alzheimer’s disease brain:
nature.com
Nature - The in-tissue architectures of β-amyloid and tau pathology in a postmortem Alzheimer’s disease donor brain are determined, showing fibril heterogeneity is spatially organized by...
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Very interesting piece of study on autopahagy and clearance of miRNA
Here's the link to my recent paper. "
https://t.co/JT4s24Ute6"
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One man's niche is another man's treasure 😀
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Excited to share our preprint! Using cryoEM to visualize details of the lipid organization within a plasma membrane microdomain. Plus, how that organization changes upon stretch!
CryoEM architecture of a native stretch-sensitive membrane microdomain https://t.co/4n62hi9QnX
#bioRxiv
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Happy to share our recent publication in the journal Infection and Immunity @ASMicrobiology @DharVinica @Shraddhagandhi5 @DBS_IISERM. Vibrio cholerae Porin OmpU Activates Dendritic Cells via TLR2 and the NLRP3 Inflammasome | Infection and Immunity
journals.asm.org
OmpU is one of the major porins of Vibrio cholerae, a Gram-negative human pathogen. Previously, we showed that OmpU stimulates host monocytes and macrophages and induces the production of proinflam...
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