Leslie Vosshall PhD
@leslievosshall
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VP/CSO @HHMInews & Head of #VosshallLab @rockefelleruniv Toward Excellent, Diverse, Equitable, Inclusive, & Open Science MASTODON: @leslievosshall @mstdn .science
Chevy Chase, MD USA
Joined April 2009
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Last Seen Profiles
Pinned Tweet
Think your lab is happy? -- ASK THEM!!
ANONYMOUS LAB SURVEY:
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Here is the front door of a C. elegans lab. These people mean business.
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We're doing a thing! Speakers
@HHMINEWS
Science Meetings will no longer put journal names on their talk slides.
Instead display first author, year, PMID (or DOI) like
@ardemp
Why?
-end prestige-signaling
-people can actually find reference
#nojournalnamesontalkslides
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I am honored and excited to be selected to succeed David Clapham as Vice President and Chief Scientific Officer of the Howard Hughes Medical Institute in 2022
@HHMINEWS
. 1/8
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As of tonight
@RockefellerUniv
has a painting that depicts women scientists, the first in its 121 year history.
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🧵📢
We need to retain talented postdocs in academic science. I'm happy to say that
@HHMINEWS
has taken a big step forward this week.
$70,000
That's the new starting minimum salary for all postdocs employed in HHMI labs
(1/4)
HHMI is implementing a new salary scale for HHMI-employed postdoctoral researchers, effective April 9, 2023. (1/4)
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It's tenure-track biomedical academic search season and "chalk talks" are right around the corner. Chalk talks are not something we "teach" our trainees and most postdocs are unprepared for them as a result.
Here are my Chalk Talk Pro Tips:
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Often a major scientific discovery can be boiled down to a
#singleplot
in a paper. Mullis & Faloona describe "polymerase-catalyzed chain reaction". We did this paper in 1st year journal club
@RockefellerUniv
and concluded that nobody would ever use this method
#PCR
PMID: 3431465
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This should have been obvious to me 20 years ago, but what happens when students/postdocs leave the lab before submitting their paper to
@biorxivpreprint
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Often a major scientific discovery can be boiled down to a single plot in a paper. This is the birth of the field of epigenetic modification of chromatin by Brownell and Allis (now
@RockefellerUniv
) PMID: 7603997. Lane 2 is histone acetyltransferase (HAT) detected by... (1 of 3)
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Think your lab is happy? -- ASK THEM!!
ANONYMOUS LAB SURVEY:
(evergreen tweet)
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I have
#COVID19
. A 🧵
I'm fine. I'm vaccinated and protected from serious disease thanks to
@moderna_tx
What I didn't expect is how people react to this news. 1/4
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Just accepted the last manuscript I am handling as Deputy Editor (cellular/molecular neuroscience)
@ScienceAdvances
before I step down to become VP/CSO of
@HHMINEWS
I handled ~1,400 manuscript 2019-2021. Wonderful to see the journal grow into a great
#OpenAccess
venue
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Often a major scientific discovery can be boiled down to a
#singleplot
in a paper. Nüsslein-Volhard, Wieschaus, & Kluding identify mutations that underlie almost every signaling pathway driving development (and cancer)
@nobelprize
no-name journal, breathtaking work
PMID: 28305337
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<Please RT> It's here!!!! - $1.5B to support early career faculty who recognize the importance of diversity in STEM and are prepared to lead happy inclusive labs as Freeman Hrabowski Scholars.
Spread the word - applications open now
HHMI expects to hire and support up to 150 early career faculty as Freeman Hrabowski Scholars – appointing 30 Scholars every other year for the next decade. Learn more here:
#FHScholars
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Did you know that
@Columbia
University was the last Ivy League to admit women? From 1754 - 1982 women were excluded. I was a member of the first co-educational class - women graduated at the top of our class. Inclusion and diversity improve institutions
#Merit
#WomenInSTEM
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Q&A with Katalin Karikó
@Vilcek
Prize recipient:
"I was quite happy without all this recognition. I didn’t even get an R01 grant in my career and, for nearly 40 years, I received virtually no awards; yet, I was glad to just to keep doing experiments."
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Set up your new lab in NYC!!!
Tenure-Track Faculty Positions
@RockefellerUniv
We have an "open search" process - we hire people, not projects. It's a great community - please apply
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🧵JUST LAUNCHED!! Freeman Hrabowski Scholars Program
#FHScholars
is the $1.5B centerpiece of
@HHMInews
#DEI
Goals supporting early career faculty committed to advancing diversity, equity, & inclusion in science (1/7) <PLEASE RT!!>
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Hi Tweeps,
I'm having fun boiling down scientific discoveries into a single plot. Someone asked if I can thread them, but instead I am hash-tagging them so you all can find them
"Often a major scientific discovery can be boiled down to a
#singleplot
in a paper."
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If you are a senior PhD graduate student, postdoc, or junior faculty in
#neuroscience
, consider adding your name to my DIY database of peer reviewers. Many academic journal editors draw from this list and you may be contacted:
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Full page ad in the A section of the
@nytimes
!
@HHMINEWS
celebrating the big
@NobelPrize
win by
@CarolynBertozzi
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Carolyn Bertozzi wins the 2022 Nobel Prize in Chemistry !!!!!!!!!!!!!!!
@HHMINEWS
@NobelPrize
@CarolynBertozzi
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OK KIDS HOW COOL IS THIS?!?!!!
Dr. Katalin Kariko
@kkariko
@RockefellerUniv
honorary degree recipient. The most inspirational
#WomenInSTEM
life journey - from marginalized to saving millions of lives
@BioNTech_Group
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It's a GO!!! First in-person Science Meeting
@HHMINEWS
in 3 years. Now with incredible touchscreen e-Posters
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Often a major scientific discovery can be boiled down to a single plot in a paper. Lane 13 is the 1991 discovery of vertebrate odorant receptors by Linda Buck and Richard Axel
@NobelPrize
PMID: 1840504
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Writing a letter of recommendation for a postdoc on the tenure-track job market?
Please check it for gender bias before you submit:
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Often a major scientific discovery can be boiled down to a single plot in a paper. siRNA 73 is the 2010 discovery of Piezo by Bertrand Coste and Ardem Patapoutian
@ardemp
@NobelPrize
PMID: 20813920
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Often a major scientific discovery can be boiled down to a
#singleplot
in a paper. Troemel and Bargmann
@betenoire1
show that when you put a receptor for a yummy smell into a yucky neuron, the yummy smell now smells yucky (neuron not receptor encodes valence) PMID: 9346234
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Monumental portrait of pioneering
#WomenInSTEM
@RockefellerUniv
by Brenda Zlamany
@BZDailyPortrait
. Hidden Figures No Longer 1/ 🧵
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It was tough being a postdoc in the 1990s. Women were invisible at my institution. What a difference 2 decades make
#WomenInSTEM
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It matters who does science
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Pure joy
@HHMINEWS
#FHScholars
IRL with Freeman Hrabowski at our in-person orientation including
@KizzyPhD
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🧵📢👇
@HHMINEWS
is incredibly excited to launch the 2024
#HannaGrayFellows
competition. $1.5M award bridging your postdoc and early career faculty years with the goal of increasing diversity in the professoriate 1/
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How can research institutions assess mentorship?
Ask former students/postdocs!!
Collect their feedback confidentially just like tenure letters. Here are 4 simple questions (with thanks to
@IGCiencia
@IGCcentrioles
for the inspiration): 1/6
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These questions are unhelpful and unanswerable.
I was one of 40,000 people who tested positive in NYC on 1/6/2022.
#Omicron
is highly contagious.
You can be positive and asymptomatic and unknowingly shed virus.
You can do everything right and still catch it. 3/4
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Important new work from
@Datta_Lab
@ShanskyLab
Overturns the dogma that females are too "complicated" to include in biomedical studies. This dogma has led to a huge disparity in clinical studies, many of which exclude women
1/2
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Charming video of Matt Meselson and Frank Stahl speaking about their 1958 experiment, which truly is the most beautiful experiment, and the beautiful friendship they have, and how playful and free science seemed to be back then
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Often a major scientific discovery can be boiled down to a single plot in a paper. Huda Zoghbi
@Baylor
showed that Rett Syndrome is caused by mutations in the X-linked gene MeCP2. C1 is the unaffected mother of two affected half-sisters (C2 and C3) with Rett. PMID: 10508514
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#OTD
2002 Society for Neuroscience Meeting: shout-out to all the parents heading to
@SfNtweets
#SfN22
next week with their kids.
So amazing that SfN now offers on-site childcare:
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Here they are!!! 31 outstanding scientists who as early career faculty with exceptional mentoring skills will build inclusive and supportive labs where all trainees thrive and persist
#FHScholars
HHMI is proud to announce our inaugural class of Freeman Hrabowski Scholars, outstanding early career faculty in science who have potential to become leaders in their research fields and to create diverse and inclusive lab environments. 1/3
#FHScholars
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Often a major scientific discovery can be boiled down to a single plot in a paper. Konopka and Benzer discover a single gene (period) that controls daily circadian rhythms in Drosophila melanogaster flies: short-day, long-day, and party-all-day-and-all-night flies. PMID: 5002428
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100% of people go immediately into blame and fault and guilt mode:
"How did you get it?"
"Who gave it to you?"
"Were you doing anything that put you at risk? Parties?"
"Were you wearing a mask?"
"Do you think you infected your family/parent/lab members/friends?" 2/4
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Celebrating BIG JOB with
@nyckevil
and a Shirley Gothic mocktail at
#lildebsoasis
"it's exactly what you think"
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One more view of the astoundingly crazy cool Mosquito Fascinator (hat) from
#VosshallLab
Wearing this to all IRL future events including royal wedding, Kentucky derby etc.
@ardemp
can you hook me up for Nobel banquet ticket
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Congratulations
@michelle_monje
Michelle Monje
@Stanford
@HHMINEWS
winner of the 2023
@theNASciences
Richard Lounsbery Award
#NAS160
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Hey we found new small molecules that suppress mosquito 🦟 appetite: 100X more potent than the OG small molecules
Congrats
@laurabduvall
!!
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Biomedical PhD with no more than 24 months of postdoc experience? Interested in learning more about the
@HHMINEWS
Hanna H. Gray Fellows program? $1.5M award that bridges postdoc to early career faculty
Join us for an informational webinar Monday 1/22/2024 3:30pm. Registration…
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Scientists mark your calendars: the next competition for
@HHMINEWS
#HannaGrayFellows
opens on August 24, 2022. This program supports scientists from the postdoc through the early career faculty stage as part of our DEI Goal 3
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📢 Please RT - incredible opportunity for 8 years of funding from postdoc>TT faculty position in the biomedical sciences
@HHMINEWS
#HannaGrayFellows
program
#DEI
Deadline is 12/7/2022
📢Deadline T minus 26 days
@HHMINEWS
#HannaGrayFellows
program
🟢 recruit and retain individuals from gender, racial, ethnic, and other groups underrepresented in the life sciences
🟢$70K salary x 4 year postdoc funding
🟢$250K/yr x 4 year faculty funding
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In case you missed today's announcement - this is likely to change how science is communicated forever. It is important. It is transformative. We have waited for this day for decades. Read this thread from
@mbeisen
, one of the most important people getting us to today.
It's worth spending some time discussing what this new
@whitehouse
Open Science policy does and doesn't do, and what is still be to determined.
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‼️ In 4 days, applications open for the 2025 Freeman Hrabowski Scholars Program
@HHMINEWS
#FHScholars
Join this cohort of outstanding early career faculty who are committed to advancing diversity, equity, and inclusion through their mentoring efforts
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Nobel Selfie!!! Congratulations David Julius
Cheers and congratulations to our newest medicine laureate David Julius!
Here Julius and his wife Holly Ingraham are celebrating his
#NobelPrize
with a cup of early morning coffee.
Photo: Holly Ingraham.
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Compelling Op-Ed piece by
@KafuiDzirasa
on the disturbing brain-drain from academic science that is weakening US competitiveness in science, and how
@NIH
can stem the outflowing tide by improving postdoc salary and benefits 1/2
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FIRST STRUCTURE OF A VERTEBRATE ODORANT RECEPTOR!!! 32 years after they were cloned by Buck and Axel. Amazing.
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Film shoot
@HHMINEWS
getting ready to announce our next HHMI Investigator Competition!!
#PeopleNotProjects
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Great visit to Texas to give the Oshman Lecture at Baylor College of Medicine
@bcmhouston
hosted by my favorite scientist and inspiring leader, physician -scientist Dr Huda Zoghbi
#womeninSTEM
@HHMINEWS
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Inspiring to see the new compensation philosophy for postdocs
@StJude
$70K starting salary - sets an important new standard
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Often a major scientific discovery can be boiled down to a single plot in a paper. Declan Doyle and Rod MacKinnon
@RockefellerUniv
show how the KcsA potassium channel selectively allows potassium ions (green spheres) but not smaller sodium ions to transit the pore. PMID: 9525859
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Just launched: 2022 Exceptional Scholars Workshop
@RockefellerUniv
This program will bring postdoctoral scientists of diverse backgrounds to our campus to share their science and participate in career workshops. We can't wait to meet you! Deadline 3/3/2022
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EXCITING NEWS FOR MOSQUITO PEOPLE
We have a new Asian Tiger mosquito (Aedes albopictus) genome. End-to-end chromosome assembly, deduplicated, fully annotated by
@NCBI
RefSeq, and gorgeous.
Congrats to
@LeahHouri
who led the effort
#VosshallLab
@HHMINEWS
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DROPPING TOMORROW
Announcement of the new class of
@HHMINEWS
#hannagrayfellows
I can't wait for all of you to meet them
#DiversityinSTEM
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Nadia Chaudhri, Scientist With an End-of-Life Mission, Dies at 43
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Purslane, a delicious semi-succulent drought-resistant wild plant that thrives in mall parking lots and highway overpasses has unlocked a new way to photosynthesize. Ideas for a new food future here
#climate
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Tour-de-force paper from Josefina del Marmol and Vanessa Ruta
@RockefellerUniv
The first structure of any odorant receptor binding a ligand. In this figure, the ligand is the bug spray DEET
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Excellent Science. Diverse Science. Open Science. Compassionate Mentoring. These important goals are not mutually exclusive. We can and will move the needle to build in all of these areas. 7/8
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Thanks so much!! I'm incredibly honored at the recognition of my lab's achievements over the past 15 years since we switched our focus to the female
#mosquito
. Can't wait to visit you all in April.
Big congrats to Dr. Leslie Vosshall for receiving the 22nd Perl/UNC Neuroscience Prize for her discovery of receptors involved in mosquito host-seeking behavior!
@leslievosshall
@HHMInews
@RockefellerUniv
.
She will visit
@UNCNeuro
on March 14, 2024 to…
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Laotian dinner at Khe Yo in Tribeca with
@ardemp
. So much delicious food and good to catch up after pandemic stopped science travel
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@nytimes
on my NYC doorstep this morning !!!!!!!
@HHMINEWS
FREEMAN HRABOWSKI SCHOLARS PROGRAM
#FHScholars
I'll explain later today what this program is and why it will be transformative
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📢Deadline T minus 26 days
@HHMINEWS
#HannaGrayFellows
program
🟢 recruit and retain individuals from gender, racial, ethnic, and other groups underrepresented in the life sciences
🟢$70K salary x 4 year postdoc funding
🟢$250K/yr x 4 year faculty funding
3
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Fantastic feature on the one and only Professor Cassandra Extavour
@redmakeda
@Harvard
@HHMINEWS
in
@QuantaMagazine
"A Multitalented Scientist Seeks the Origins of Multicellularity"
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Yay
@ardemp
congratulations!!!!!!!! Love the 3AM family photo so much
Just in! New medicine laureate Ardem Patapoutian and his son Luca, watching the
#NobelPrize
press conference shortly after finding out the happy news.
Stay tuned for our interview with Patapoutian coming up soon!
Photographer: Nancy Hong
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Often a major scientific discovery can be boiled down to a single plot in a paper. Del Marmol (
@MarmolJosefina
) and Ruta
@RockefellerUniv
show that an odor opens the ion-conducting pore of an insect odorant receptor
Fun fact: people used to think these were GPCRs!
PMID: 34349260
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The new
@HHMINEWS
salary scale has the flexibility to bring on new postdocs at up to $91,000 in high cost of labor areas where private industry competes with academia for the best scientists (2/4)
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If you are
@RockefellerUniv
check out the new Prize Wall, now finally featuring our prominent
#WomenInSTEM
including
@betenoire1
, Titia de Lange, and Elaine Fuchs
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HERE THEY ARE!!
These 25 new
#HannaGrayFellows
are doing amazing science and bring welcome diversity to the biomedical sciences. I can't wait to see what they do!
Meet the 2022
#HannaGrayFellows
!
These talented postdoctoral scientists represent a promising and more diverse future for biomedical science.
Learn more about them at
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Presenting Dr. Nipun Basrur
@nipunbasrur
, who impressed everyone with his incredible PhD defense
@RockefellerUniv
today !! Deepest thanks to thesis committee members
@erichjarvis
#VanessaRuta
@lizzyzhao
and esteemed external examiner
@HarmitMalik
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Dear 🌎 allow me to introduce Dr. Krithika Venkataraman, PhD
@kritvenks
!!
Excellent thesis talk and expertly handled defense with
@hopihoekstra
@DanielKronauer
@shahamlab
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More data proving that standardized tests are highly sensitive instruments for predicting family income. Not educational attainment or academic promise.
#Thread
Thread: A slow weekend turned interesting when a student at Columbia, in response to a tweet suggesting the SAT and ACT were "good, actually" posted this chart.
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Inaugural Freeman Hrabowski Scholars Poised To Make Great Advances In Science And Equity via
@forbes
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Back
@HHMINEWS
Headquarters where we continue to celebrate the 2022
#GilliamFellows
including
@laurennealneuro
here on the hallway jumbotron!!!
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Please RT
#VosshallLab
is hiring! This is a research/leadership/ mentorship position similar to a staff scientist. A great opportunity to carry out independent research and mentor early career scientists in the lab.
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Late to the party, just to say that this is changing biology as we know it.
Protein complex prediction with AlphaFold-Multimer
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Often a major scientific discovery can be boiled down to a single plot in a paper. Marshall W. Nirenberg and J. Heinrich Matthaei show that UUU encodes Phenylalanine, the first glimpse of the genetic code. Nirenberg, but not Matthaei, was awarded the
@NobelPrize
. PMID: 14479932
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