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Ben Rome Profile
Ben Rome

@bnrome

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@bnrome
Ben Rome
1 year
📺 Tune in at 2PM as I talk with the House @WaysMeansCmte Health Subcommittee about high drug prices, PBMs, and rebates! 💊💵
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@bnrome
Ben Rome
3 years
My hospital system @MassGenBrigham is now vaccinating all employees, including those who work from home and have no clinical responsibilities. We haven’t yet started vaccinating high-risk patients. If we have extra doses, we should return them to the state for re-allocation.
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@bnrome
Ben Rome
2 years
Is your team role identified on your hospital ID badge??? Now out in @JAMANetworkOpen , we describe our experience rolling out Doctor badges to residents at BWH & MGH. Are these badges helpful?? Read on to find out 👇👇👇 1/
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@bnrome
Ben Rome
8 months
Now begins the most awkward period in any relationship: When 1 person dumps the other but they still have to live together for 5 years until the lease runs out…
@BostonGlobe
The Boston Globe
8 months
Dana-Farber Cancer Institute and Beth Israel Deaconess Medical Center have announced plans to build a new inpatient hospital for adult cancer care in Boston, breaking the cancer hospital’s almost 30-year relationship with Brigham and Women’s.
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@bnrome
Ben Rome
3 years
Hate to say it, but if Donald Trump had started recommending #Booster vaccines before @US_FDA or @CDCgov weighed in, there would have been outrage. A few thoughts 👇
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@bnrome
Ben Rome
2 years
🚨NEW PAPER🚨out today in @JAMA_current ➡️Average prices for new drugs have increased 20%/year from 2008-2021!!! 💊💰📈 ➡️In 2020-21, ~HALF of new drugs cost >$150k/yr (vs 9% in 2008-13)! 🔗 A few thoughts 👇
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@bnrome
Ben Rome
5 years
Our new @JAMAInternalMed article shows how "Doctor" ID badges can reduce role misidentification, particularly among female residents. Great team, including @ersied727 @MariaYialamas @SanjayDivakaran . @womeninmedchat #womeninmedicine
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@bnrome
Ben Rome
2 years
“Sorry for the confusion… we have no plans to change our practice of charging unbelievably high prices for a century-old drug.”
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@bnrome
Ben Rome
9 months
Someone forgot to tell the @nytimes graphics editor that the GLP1 drugs are injections, not pills…
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@bnrome
Ben Rome
3 years
Some exciting personal news to share — I’m thrilled to have joined the faculty at @PORTAL_Research ! Looking forward to continued work with @akesselheim , Jerry Avorn, @AmeetSarpatwari , @JonathanDarrow , and all the other brilliant and wonderful faculty at DoPE!
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@bnrome
Ben Rome
4 years
In a journal club with @harvardmed students last week we talked about this issue — death can’t be a censoring event in an analysis of clinical improvement. These letters all raise points that should have made @NEJM think twice before publishing an industry-funded case series.
@djc795
David J. Cohen, MD, MSc
4 years
So, apparently, the statistics in the NEJM report on compassionate use remdesivir without a control group were wrong. 53 authors and not one knows how to conduct a Kaplan-Meier analysis??
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@bnrome
Ben Rome
3 years
Any comment, @BrighamWomens ?
@MassGeneralNews
MassGeneral News
3 years
We could use a little help with today’s @nytimes crossword.
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@bnrome
Ben Rome
3 years
Today I graduate with my MPH from @HarvardChanSPH ! Feeling immense gratitude to my mentors, the faculty and students at HSPH, and my friends and family for their support! (Probably my last degree, but definitely not the end of my educational journey!)
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@bnrome
Ben Rome
2 years
Truly an honor to be recognized by @VictorDzau as an Emerging Leader in Health and Medicine scholar at @theNAMedicine annual meeting. Such an inspiring group of colleagues. Thanks @akesselheim for the mentorship and nomination! And to my family and @PORTAL_Research colleagues.
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@bnrome
Ben Rome
3 years
A gentle and kind soul has been taken way too early. I’ll miss you, @wshraun . 💔 #brighamfamily
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@bnrome
Ben Rome
4 years
Just spent 2 hours reformatting a manuscript / tables / figures for a different journal. 😤 There must be a better way!!
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@bnrome
Ben Rome
3 years
We know that HCQ isn't effective for Covid-19... but that hasn't stopped people from using it! NEW in @JournalGIM - @akesselheim Jerry Avorn and I examined which patients and prescribers used HCQ during the pandemic. 📜(free to read): 🔑findings 👇
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@bnrome
Ben Rome
9 months
A lot of people are framing today’s list as choices CMS made. That’s a bad framing. Congress gave very explicit instruction to CMS about how to select drugs. There isn’t a lot of wiggle room. We summarized the selection rules in our simulation:
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@bnrome
Ben Rome
2 years
Dear editors, Saturday morning is the WRONG time to send proofs with a 48hr turnaround. Sincerely, Academics everywhere
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@bnrome
Ben Rome
9 months
Tomorrow @JoeBiden announces the first 10 drugs to face Medicare price negotiation. According to predictions from the team at @PORTAL_Research , here’s the most likely drugs to be selected: Eliquis Enbrel Ibrance Imbruvica Januvia Jardiance Myrbetriq Trulicity Xarelto Xtandi
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@bnrome
Ben Rome
9 months
So just to be clear, @MassGenBrigham is: ➡️ Cutting health care benefits for employees. ➡️ Bumping pay for top execs. Cool. Good plan.
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@bnrome
Ben Rome
4 years
What monster designing SAS decided to put the “clear all” button right next to “run”?? 😖 #epitwitter #SAS
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@bnrome
Ben Rome
2 years
8/ In summary: In this large prospective study of residents in multiple specialties, we found that Doctor badges were a simple, low-cost tool that reduced role misidentification, particularly among female residents.
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@bnrome
Ben Rome
1 year
In 2014, we founded the BWH house staff council to get trainee voices at the table. We had some important short-term wins: long-term disability coverage, 9pm meal. But the fact that residents want to unionize suggests that there’s still a lot of room to go. 1/
@MGBUnited
MGB Housestaff United
1 year
It's official! MGB Housestaff United has filed for an election with the National Labor Relations Board! We are voting YES!
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@bnrome
Ben Rome
3 years
Five years ago today… starting intern year on #OncNights @BrighamMedRes ! Good luck to all the interns embarking on the rewarding, challenging, and humbling journey that is residency!! #NeverWorryAlone
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@bnrome
Ben Rome
9 months
Really exciting to see this momentous step for the Medicare program. Some quick reactions to this first list of 10 drugs: 1. Many drugs are no surprise - especially Eliquis, Xarelto, Januvia, Jardiance, and Imbruvica. All widely expected to make this list
@ZacharyBrennan
Zach Brennan
9 months
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@bnrome
Ben Rome
4 years
🚨TODAY at 1:30PM ET I’ll be testifying before the @HouseScience Investigations and Oversight Subcomittee hearing about repurposing drugs to treat #COVID19 . Tune in to the livestream 👇
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@bnrome
Ben Rome
3 years
@VPrasadMDMPH Shouldn't you be asking this first?
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@bnrome
Ben Rome
1 year
@S__Baksh Does MGB negotiate with individual residents or groups of residents now about salary, benefits, or work environment?
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@bnrome
Ben Rome
4 years
This misses the point. The concern isn’t that this will slow down FDA decisions. It’s that this threatens @US_FDA independence and could lead to decisions based on politics and not science.
@SpoxHHS
ARCHIVED: HHS Office of Public Affairs
4 years
Yet another misleading story that risks undermining the public health response while relying on uninformed anonymous sources. The memo maligned in this story is a good governance, housekeeping action, which will not slow down the important work of the FDA or any HHS division. 1/2
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@bnrome
Ben Rome
3 years
My wife is 6 months into oncology fellowship and this is today’s mail... There’s gotta be a more environmentally friendly way, no?? #savethetrees 🌲🌳
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@bnrome
Ben Rome
2 years
Honored and excited to be a part of this amazing program for the next 3 years. Thanks @theNAMedicine for the opportunity and @akesselheim for the nomination.
@theNAMedicine
National Academy of Medicine
2 years
Announcing @theNAMedicine Emerging Leaders in Health and Medicine! The Scholars are part of a new generation of leaders poised to shape the future of science, medicine, and health equity. Meet the Scholars: #NAMEmergingLeaders
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@bnrome
Ben Rome
2 years
Awesome presentation by @tmmeade1 about @BrighamMedRes efforts to improve ambulatory care of resident patients. #SGIM22 #HamolskyFinalist
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@bnrome
Ben Rome
2 years
Here we go! #SGIM22
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@bnrome
Ben Rome
1 year
Who’s gonna tell him that even if expensive drugs are fully covered by insurance, they still make health care unaffordable?? We all pay for these billions of dollars from patent gaming through taxes, lost wages, premiums. Not just those who need Humira.
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@bnrome
Ben Rome
2 years
🚨New in @JAMA_current 🚨 New Reforms to Prescription Drug Pricing in the US Opportunities and Challenges Our take on the monumental Inflation Reduction Act drug pricing reforms. Bonus🎙️ interview with @akesselheim . Led by @thomasmd @PORTAL_Research .
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@bnrome
Ben Rome
1 year
🚨NEW PAPER🚨 out today in @JAMAHealthForum Under the #InflationReductionAct , Medicare will soon start negotiating drug prices. How will this work?? We dive deep using a historical simulation. 🧵👇 📜:
@JAMAHealthForum
JAMA Health Forum
1 year
Medicare price negotiation under the #InflationReductionAct could reduce prescription drug spending by at least 5% in the first 3 years, according to a simulation study. @bnrome @PORTAL_Research
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@bnrome
Ben Rome
4 years
In clinic this week I got to *actually* use one of the best ICD10 codes I’ve come across: “W56.02XA — Struck by Dolphin, initial Encounter” 🐬🐬🐬 #medtwitter #accuratebilling
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@bnrome
Ben Rome
3 years
Dr. Marty was a gem of a physician and a phenomenal human being who contributed so much to the @BrighamMedRes community. So saddened by this devastating loss.
@rafaelmarty
Rafael Marty
3 years
Hoy en la ciudad de Santo Domingo, República Dominicana, murió mi hermano mayor Francisco Miguel Marty Forero por un accidente, prestigioso médico venezolano infectólogo, PAZ A SU ALMA
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@bnrome
Ben Rome
3 years
In summary: 1⃣Booster vaccines probably safe, but effectiveness unknown. 2⃣Unclear if boosters are needed (e.g. does immunity wane over time). 3⃣Offering booster vaccines in the US now may delay vaccine uptake in the rest of the world. 6/
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@bnrome
Ben Rome
1 year
Grateful for the opportunity to talk on behalf of millions of patients who struggle to afford their prescription drugs. The #InflationReductionAct was a great start. Let’s keep pushing for more changes to lower prices! ICYMI (37:55) -
@bnrome
Ben Rome
1 year
📺 Tune in at 2PM as I talk with the House @WaysMeansCmte Health Subcommittee about high drug prices, PBMs, and rebates! 💊💵
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@bnrome
Ben Rome
3 years
This isn't a simple question of "following the science." It's a complex public health decision that should be analyzed through multiple lenses. For such a complex issue, this is a clumsy role out by the @WhiteHouse . 7/7
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@bnrome
Ben Rome
8 months
I was tongue in cheek with my post yesterday But seriously, I’m worried about the profound effect this change will have, particularly for @BrighamMedRes . Onc was such a huge part of my training. Including my first intern rotation on Onc nightfloat (with @MattRamsisMD ).
@bnrome
Ben Rome
8 months
Now begins the most awkward period in any relationship: When 1 person dumps the other but they still have to live together for 5 years until the lease runs out…
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@bnrome
Ben Rome
1 year
Great to hear from former FDA commissioner @ScottGottliebMD today at the @theNAMedicine Emerging Leaders forum. 📷 with PORTAL fellow @DrHussainL
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@bnrome
Ben Rome
3 years
NEW PAPER in Am Heart J re 💊💰 We found that AFib patients with higher #NOAC copayments had lower adherence. Drugs only work if patients can afford to take them! @akesselheim @PORTAL_Research
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@bnrome
Ben Rome
2 years
Nearly 2 years into this pandemic, why is it so difficult to get a COVID test? This is a huge public health failure.
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@bnrome
Ben Rome
2 years
10/ Completing this study was a heroic 5-year team effort by @MikeFooteMD Nina Jain @ersied727 @MariaYialamas @CEPoweMD . 🙏 to @SanjayDivakaran @SophiaKMcKinley @BrighamMedRes @DouglasBJacobs @vawilmarth and many others not on Twitter!
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@bnrome
Ben Rome
1 year
When you miss 1 of the 10 questions on the Health Streams module pre-test…
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@bnrome
Ben Rome
2 years
Plenary talk by superstar @IshaniG highlighting cascades of care following screening breast MRI vs mammogram. #SGIM22
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@bnrome
Ben Rome
2 years
3/ We reported initial results in @JAMAInternalMed 🔵45% reported at least weekly role misidentification. 🔵Female residents 3.6x more likely to report misidentification 🔵 82% of female residents reported reduced misidentification after Doctor badge
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@bnrome
Ben Rome
4 years
@EricTopol @NEJM Glad this data is being collected, but without control group it’s VERY limited. Most important sentence: “data from several ongoing randomized, controlled trials will soon provide more informative evidence regarding the safety and efficacy of remdesivir for Covid-19.”
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@bnrome
Ben Rome
3 years
Both @pfizer and @moderna_tx vaccines are ~95% effective. How do they size up re side effects? - Vaccines hurt your arm (duh!) - Few systemic side effects with dose 1 - More systemic side effects with dose 2 - Most side effects MILD Tl;dr - Get vaccinated. Either one!
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@bnrome
Ben Rome
3 years
This is sad. Retracted @NEJM paper based on falsified data continues to be cited 1 year later. Often with no mention of the retraction. via @JAMAInternalMed part of @JAMANetwork
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@bnrome
Ben Rome
2 years
Wow, hard to believe that mindfulness curriculum isn’t the solution to resident burnout 🤦 Cc @DGlaucomflecken
@JAMAPediatrics
JAMA Pediatrics
2 years
A cluster randomized controlled trial of a novel mindfulness curriculum found no impact on pediatric intern burnout, mindfulness, or empathy. Ongoing research is needed to identify interventions that decrease burnout among trainees. @FraimanYarden
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@bnrome
Ben Rome
2 years
It’s that time of year when for about 30 seconds I become an expert in the different types of fire extinguishers. 🧯
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@bnrome
Ben Rome
9 months
Scott this is garbage spin, not analysis. The criteria aren’t unpredictable. CMS is just using more recent data than anyone else has access to. Enbrel and Entresto aren’t surprising at all. Farxiga and Stelara a little more so but sales of both have surged in the last 2 years.
@ScottGottliebMD
Scott Gottlieb, MD
9 months
Some surprises on list of 10 drugs that Medicare will set prices for. Many expected Ofev, Pomalyst, Xtandi, Invega to be on list. Instead Farxiga, Entresto, Enbrel, Stelara added. Those were expected to make list in 2027. It shows that Medicare's criteria is still not predictable
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@bnrome
Ben Rome
2 years
I’m not sure you could’ve convinced me that any news story this year about B-amyloid in Alzheimer’s could have been more scandalous than the FDA Aduhelm disaster… …but this story absolutely is.
@awaisaftab
Awais Aftab
2 years
Shocking! There are serious concerns that key images may have been fabricated in multiple influential papers pertaining to the amyloid hypothesis of Alzheimer’s, and that this may have misdirected subsequent research efforts for the last 16 years
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@bnrome
Ben Rome
4 years
@rose_m_olson Those HPIs are also the primary reason Ortho consults ID
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@bnrome
Ben Rome
2 years
Huge thanks to @akesselheim for the nomination and mentorship! Excited for this opportunity to connect with a really amazing group of colleagues.
@akesselheim
Aaron Kesselheim
2 years
Congrats to @bnrome at @PORTAL_Research for being selected to the 2022 class of @theNAMedicine Emerging Leaders in Health and Medicine! Very well deserved honor and impressive group of scholar-leaders:
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@bnrome
Ben Rome
1 year
Pharma routinely argues that high prices are need to recoup expensive R&D costs. But that isn’t true. In reality, they choose prices to maximize revenue. Aduhelm, case and point 👇👇👇
@damiangarde
Damian Garde
1 year
The documents provide a rare glimpse at how drug companies decide on prices. Biogen surveyed insurers and neurologists, learning that anything over about $40,000 would be perceived as “overpriced.”
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@bnrome
Ben Rome
2 years
5/ So what’s the solution??? Why not negotiate prices of newly approved drugs based on evidence of clinical benefit? In fact, the US is the only high-income country that DOESN’T evaluate and negotiate prices for new drugs. 📄 @ZekeEmanuel
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@bnrome
Ben Rome
3 years
Excellent reporting by @GlobeSpotlight 🌎 🔦 It’s time for @MassGenBrigham and other Boston hospitals to rethink COI policy for execs. If pharma-sponsored lunches and pens aren’t acceptable, neither should millions of 💵 for sitting on a board.
@BostonGlobe
The Boston Globe
3 years
From @GlobeSpotlight : Boston’s hospital chiefs moonlight on corporate boards at rates far beyond the national rate.
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@bnrome
Ben Rome
2 years
New @OIGatHHS report estimates that Medicare and Medicaid spent $18B on accelerated approval drugs with unconfirmed clinical benefit from 2018-2021! Few thoughts 👇
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@bnrome
Ben Rome
4 years
@francisdeng The reason USMLE was comfortable making this change is because they don’t lose any money. 100% of students still need to take it regardless of scoring... but I’m with you. Curious to see what comes next.
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@bnrome
Ben Rome
5 years
Excited to share our new study in @JournalGIM (with @DrStephMueller ) about duplicate imaging ordered after inter-hospital transfer. Bottom Line: 1 in 4 patients had 1+ duplicate imaging study, and real-time shared EHR data may help...
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@bnrome
Ben Rome
3 years
🚨NEW PAPER🚨 in @Health_Affairs Led by superstar HS student Aayan Patel, we found that *1 in 5* generic drugs had a price spike (doubled in <1yr) from 2014-17. 💊🏷📈 With @akesselheim 🔗 Brief highlights in 🧵👇
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@bnrome
Ben Rome
3 years
@walidgellad @MassGenBrigham Great to hear. @MassGovernor has been holding onto a tiered vaccine roll out despite the new federal recommendations to vaccinate all >65. Seems like they allocated too many doses to big hospital systems, and those hospitals are using the tiers to justify not vaccinating pts.
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@bnrome
Ben Rome
3 years
Amazing how Pfizer is super interested in studying a booster dose… …but not studying the efficacy of a single dose strategy. Financial incentives matter.
@EricTopol
Eric Topol
3 years
Pfizer plans to file an EUA for a booster vaccine to counter Delta (+ do a clinical trial) There are currently insufficient data to warrant that it'll be necessary. Beyond neutralizing antibodies, our immune response consists of memory B cells, T cells
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@bnrome
Ben Rome
2 years
9/ Since this study, @BrighamWomens has started distributing role identification badges to ALL patient-facing staff. Hopefully our findings will convince other academic medical centers to follow suit.
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@bnrome
Ben Rome
1 year
🗞️New Paper🗞️ in @JAMAInternalMed Humira is the biggest blockbuster drug of all time. 💊💰 So why did Medicaid spending for Humira spike by $4.4B from 2018-21??? 🤔 Read the 🧵 to find out 👇👇👇! 📃 @PORTAL_Research @akesselheim @charliecwlee
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@bnrome
Ben Rome
2 years
He was there to promote #drugprice reform!
@choo_ek
Esther Choo, MD MPH
2 years
Okay now we're just waiting to hear who the little kid with the blue tie is #SOTU
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@bnrome
Ben Rome
9 months
Out now in @JAMA_current , Alex Egilman, @akesselheim , and I defend the use of foreign HTA assessments to evaluate drugs' clinical benefit. And we argue that the US should get in the HTA game like all our peer countries! @PORTAL_Research
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@bnrome
Ben Rome
1 year
5/ The fact that some MGB leaders believe that a union will harm teaching and mentoring is truly sad and disappointing. As a faculty, I’ll 100% support residents and trainees, regardless of whether a union passes. That is our duty.
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@bnrome
Ben Rome
1 year
This is a 🔥 take. Non-profit hospitals blame their current financial woes on 📈 labor costs and 📉 clinical revenue. But maybe it’s actually just from 📉 investments because the markets are down.
@GeBaiDC
Ge Bai
1 year
Here is the link to our @Health_Affairs Forefront study, coauthored with @CM_Whaley & Sebahattin Demirkan:
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@bnrome
Ben Rome
4 years
Fantastic @NBCNightlyNews coverage of work by @ChanaSacks and @akesselheim (in @JAMA_current ) Bottom line: Combination 💊 often much more expensive, leading to $1 billion in excess Medicare spending in 2016! 💰💰💰
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@bnrome
Ben Rome
1 year
So what did we learn from this momentous CMS guidance about the drug price negotiation process? Here's a brief 🧵with some early cliff notes. No way I can adequately capture 93 dense technical pages in Tweet form, but here goes nothing... 👇👇
@bnrome
Ben Rome
1 year
Too much @CMSGov #DrugPricing news for 1 day?? New guidance on how CMS will negotiate drug prices. Initial observation: Offer will be based on net prices of therapeutic alternatives. More thoughts once I dig in further!
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@bnrome
Ben Rome
3 years
Based on Pfizer CEO comments, it sounds like the we'll soon have data showing that booster vaccines increases antibody response. This is a surrogate measure for what we really care about -- reducing serious infections and (hopefully) transmission. 2/
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@bnrome
Ben Rome
5 years
Just finished my first day as an *attending* PCP @TheJenCenter ! Grateful to all the staff who are helping me get accustomed, and feeling lucky to care for some amazing patients.
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@bnrome
Ben Rome
3 years
It’s a fallacy that making an ineffective drug available is good for patients... these drugs cause side effects and contribute to financial toxicity. @US_FDA should protect patients by requiring evidence of efficacy and safety. Cc @oncology_bg @VPrasadMDMPH
@ZacharyBrennan
Zach Brennan
3 years
ODAC votes to keep Keytruda and Tecentriq accelerated approvals in bladder cancer -
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@bnrome
Ben Rome
1 year
Exciting new proposals from @CMSinnovates 1️⃣ $2 generic drug list for part D 2️⃣ New payment models for cell/gene therapies 3️⃣ altering payment for accelerated approval drugs to incentivize faster post-market evidence
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@bnrome
Ben Rome
3 years
This week I one of my MCR patients stopped taking his GLP1ra because it was costing him >$300/mo. His insulin is >$100/mo and I learned today it will be (slightly) cheaper if he goes to Walmart and pays cash. We cannot go on like this. We need #PartD reform. Badly.
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@bnrome
Ben Rome
8 months
Is this the first academic publication co-authored by @mcuban ??
@PMCram
Peter Cram
8 months
Comparison of Hospital Online Price and Telephone Price for Shoppable Services from outstanding @utmbhealth medical student Merina Thomas @UTMBGenMed @UTMBProvost
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@bnrome
Ben Rome
1 year
Well that pretty much sums it up… coming out next week in @Health_Affairs 😉 #OpenAI 🤖
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@bnrome
Ben Rome
3 years
"We cannot let this regulatory erosion send us back to a pre-thalidomide era." @akesselheim and #JerryAvorn via @nytimes
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@bnrome
Ben Rome
2 years
2/ This idea started back in 2017-18. Based on anecdotes from female colleagues about frequently being misidentified by patients and other staff as non-physician team members. With support from @DrJoelKatz & @MariaYialamas , we distributed Doctor badges to @BrighamMedRes
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@bnrome
Ben Rome
4 years
“Powerful” antibodies? Seems like @nytimes is doing some marketing for @Regeneron . What’s a non-powerful antibody??
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