JAMA Internal Medicine
@JAMAInternalMed
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JAMA Internal Medicine is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.
Chicago, IL
Joined July 2009
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Urgency is not an emergency. Using IV
#drugs
for hypertensive urgency can lead to more harm than good
@IcahnMountSinai
#highvaluecare
1
530
617
Study findings do not support the treatment of elevated inpatient blood pressures in hospitalized older adults without evidence of end organ damage and highlight the need for randomized clinical trials of inpatient blood pressure treatment targets.
6
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505
JAMA Internal Medicine introduces a new series, the Guide to Statistics and Methods, to be accessible to clinicians and researchers contextualizing and interpreting statistical methods applied in studies published in JAMA Internal Medicine.
3
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305
Findings suggest that older patients, particularly those with limited autonomy, who spend the night in the ED awaiting hospital admission may have a higher risk of in-hospital mortality and morbidity; they should be prioritized for admission to a ward.
8
131
254
#Hypertension
is common in the inpatient setting, but antihypertensive intensification is not. Intensification of therapy without signs of end-organ damage is associated with worse outcomes
4
89
208
Defecation-induced cardiac arrest is an unrecognized cause of sudden cardiac death in patients with advanced cardiomyopathy. An increase in parasympathetic tone with sympathetic withdrawal is suggested. In contrast to atropine, epinephrine should be used
20
62
186
In this randomized clinical trial, a 5-day course of oral ivermectin administered during the first week of
#COVID19
illness did not reduce the risk of developing severe disease, when compared with standard of care alone.
15
140
176
The generic names of many new drugs are unpronounceable. It is embarrassing and unsafe for patients. Let's fix this.
10
161
178
Topical NSAIDs are associated with greater pain relief without increase in adverse events when treating musculoskeletal conditions such as sprains, strains, and contusions.
8
120
168
This study found that 46% of all meta-analysis publications of the ARISTOTLE clinical trial had conclusions altered by publications with falsified data, and 32% of all the analyses had a considerable change in the outcome.
6
146
164
An AI chatbot generated quality & empathetic responses to patient questions posed in an online forum, finds study. Chatbot-generated responses were preferred to physician responses. Further exploration of this tech is necessary.
#artificialintelligence
5
68
156
Findings of this meta-analysis suggest that colorectal cancer screening with sigmoidoscopy may extend life by approximately 3 months; lifetime gain for other screening tests appears to be unlikely or uncertain.
5
81
158
The great
@sarahkliff
on the high costs of ED care and surprise medical billing and lessons learned from her
@voxdotcom
reporting on the practice
2
52
153
Overdiagnosis of penicillin allergies leads to adverse consequences in the pre-op setting
3
170
146
Diabetic Foot Guidelines: Test patients w
#diabetes
for peripheral neuropathy using the Semmes-Weinstein test
2
121
144
Older adults taking statins for primary prevention may not benefit according to re-analysis of SPRINT trial data.
1
142
143
Study suggests that the Epic Sepsis Model poorly predicts
#sepsis
; its widespread adoption despite poor performance raises fundamental concerns about sepsis management on a national level
1
45
139
Dr.
@sharon_inouye
will become the Editor in Chief of JAMA Internal Medicine. Dr. Inouye is an internationally recognized leader in geriatric medicine and aging research.
4
26
135
In this randomized clinical trial of overweight adults who habitually sleep <6.5 hours per night, sleep extension reduced daily energy intake by ~270 kcal. Maintaining adequate sleep duration could be a viable intervention to prevent or reverse obesity.
0
36
129
Over the course of AY2016-2017, some internal medicine residents in a single academic medical center ordered an astonishing 7-8 times more diagnostic tests than their peers. Read the details here
#lessismore
10
68
125
2017 Hypertension Guideline
Begin meds if
- Clinical CVD or
- 10y ASCVD risk >= 10% AND SBP >=130 mm Hg / DBP >= 80 mm Hg or
- 10y ASCVD risk >= 10% AND SBP >=140 mm Hg / DBP >= 90 mm Hg or
1st-line meds =
- Thiazides
- CCBs
- ACE inhibitors or ARBs
0
104
122
After 14 years, JAMA Internal Medicine Editor
@RFRedberg
stepping down June 2023. Editorial milestones include
#impactfactor
44.46; 15M+ annual article downloads;
#LessIsMore
series discussing unnecessary medical tests;
#research
on important topics like health care reform.
7
14
124
Evidence-Based Guidelines to Eliminate Repetitive Laboratory Testing
0
104
113
2017 Hypertension Guideline
Begin meds if
- Clinical CVD or
- 10y ASCVD risk >= 10% AND SBP >=130 mm Hg / DBP >= 80 mm Hg or
- 10y ASCVD risk >= 10% AND SBP >=140 mm Hg / DBP >= 90 mm Hg or
1st-line meds =
- Thiazides
- CCBs
- ACE inhibitors or ARBs
0
106
120
The Role of P Values and Hypothesis Tests in Clinical Research
2
111
119
Too Good To Be True? Helmet non-invasive ventilation reduced intubation and mortality
6
134
114
Overdiagnosis of penicillin allergies leads to adverse consequences in the pre-op setting
2
145
112
Diabetic Foot Guidelines: Test patients w
#diabetes
for peripheral neuropathy using the Semmes-Weinstein test
1
93
112
The AST and ALT are a little elevated - now what? When the test of time may be a more useful and less harmful diagnostic tool: a Teachable Moment on the step-wise evaluation of mildly elevated transaminases.
@grammargandhi
@NilooLatifi
#highvaluecare
0
56
113
Treat benign paroxysmal positional
#vertigo
with the Epley maneuver
http://t.co/3sZIMb3Csq
#BPV
#epley
http://t.co/4p9x4T8RB2
0
108
112
Benefits of physical activity have a threshold; a dose-response relationship study
http://t.co/prUmZJQtor
http://t.co/Zlh4HoFT04
3
202
107
This cohort study found overestimation of arterial oxygen saturation levels by pulse oximetry occurred in Asian, Black, and Hispanic patients with
#COVID19
and delayed care compared with White patients.
@AshFawzyMD
@GoldenSherita
@AmandaBradke
@BTGaribaldi
4
56
103
A form of intermittent fasting called early time-restricted feeding (eTRE) was more effective for losing weight, lowering diastolic blood pressure, and improving mood than eating over a ≥12-hour window.
4
40
103
The generic names of many new drugs are unpronounceable. It is embarrassing and unsafe for patients. Let's fix this.
3
110
101
Primary preventive BP lowering prevent death and cardiovascular disease only when SBP is above 140 mmHg
1
93
100
Did You Know? New studies indicate that the gut
#microbiome
can influence the effectiveness of
#cancer
immunotherapy and manipulating gut bacteria might expand the population of patients who benefit from treatment
#PD1Inhibitors
0
68
93
Diabetic Foot Guidelines: Test patients w
#diabetes
for peripheral neuropathy using the Semmes-Weinstein test
2
60
99
ChatGPT wrote History of Present Illness summaries that were comparable to those written by senior internal medicine residents.
5
24
99
Most clinicians rarely use statistical terms to explain treatments, and overestimate of harm & benefits
1
110
97
Evidence-Based Guidelines to Eliminate Repetitive Laboratory Testing
0
95
93
Diabetic Foot Guidelines: Test patients w
#diabetes
for peripheral neuropathy using the Semmes-Weinstein test
0
59
90
Who needs a nutritional
#supplement
? Almost no one. Yet millions of Americans spend $$$ on vitamins & supplements without any
#evidence
of benefit. Read our patient page on the subject for more information & help deciding if you can toss that multivitamin
6
82
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Evidence-Based Guidelines to Eliminate Repetitive Laboratory Testing
0
71
88
It doesn't have to be in PubMed to count as a citation -
Medical Cannabis Laws and Opioid Mortality
0
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84
Evidence-Based Guidelines to Eliminate Repetitive Laboratory Testing
0
62
82
Given what we now know about disease processes, an understanding of nutrition is as key to medical practice as an understanding of pharmaceuticals
2
33
84
Delirium associated with accelerated cognitive decline that continued for 72 months following the index delirium episode; it's uncertain if delirium causes cognitive decline or if pts with preclinical brain disease are more likely to develop delirium.
0
41
81
2017 Hypertension Guideline
Begin meds if
- Clinical CVD or
- 10y ASCVD risk >= 10% AND SBP >=130 mm Hg / DBP >= 80 mm Hg or
- 10y ASCVD risk >= 10% AND SBP >=140 mm Hg / DBP >= 90 mm Hg or
1st-line meds =
- Thiazides
- CCBs
- ACE inhibitors or ARBs
3
74
83
Many patients are on multiple medications. Over time, some medications that were once helpful may no longer be needed. Safely lowering or stopping unnecessary medications is called deprescribing. Find out more with this JAMA Patient Page.
0
42
83
Older adults taking statins for primary prevention may not benefit according to re-analysis of SPRINT trial data.
1
67
81
2017 Hypertension Guideline
Begin meds if
- Clinical CVD or
- 10y ASCVD risk >= 10% AND SBP >=130 mm Hg / DBP >= 80 mm Hg or
- 10y ASCVD risk >= 10% AND SBP >=140 mm Hg / DBP >= 90 mm Hg or
1st-line meds =
- Thiazides
- CCBs
- ACE inhibitors or ARBs
1
56
83
Evidence-Based Guidelines to Eliminate Repetitive Laboratory Testing
0
60
79
Most new drugs fail to show adequate efficacy, safety in late-stage clinical trials
5
83
80
Clinical Review: Management of Asthma in Adults
0
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78
#Hydroxychloroquine
taken daily by hospital-based health care providers over 8 weeks did not prevent
#SARSCoV2
infection, in a double-blind randomized placebo-controlled trial performed at 2 University of Pennsylvania hospitals
10
51
76
Clinicians should verify the validity & impact of machine learning methods just as they would any other diagnostic or prognostic tool in
@JAMA_current
0
45
80
How to Read a Systematic Review and Meta-analysis and Apply the Results to Patient Care
0
99
78
No benefit found when pravastatin used for primary prevention in adults w/ moderate hyperlipidemia & hypertension
6
71
75
Older adults taking statins for primary prevention may not benefit according to re-analysis of SPRINT trial data.
1
76
76
In this randomized clinical trial, a hospital ward-based improvement program did not result in a reduction in most hospital-associated complications in older adults, although there was a significant reduction in delirium.
1
34
75
Cancer Screening, Overdiagnosis, and Regulatory Capture
0
69
75
Older adults taking
#statins
for primary prevention may not benefit according to re-analysis of SPRINT trial data.
0
82
76
#Hydroxychloroquine
taken daily by hospital-based health care providers over 8 weeks did not prevent
#SARSCoV2
infection, in a double-blind randomized placebo-controlled trial performed at 2 University of Pennsylvania hospitals
1
71
74
Topical NSAIDs are associated with greater pain relief without increase in adverse events when treating musculoskeletal conditions such as sprains, strains, and contusions.
3
59
73
Comparison of patients just either side of the +ve D-dimer cutoff - who differ markedly in their probability of CTPA scan but are otherwise similar - found no eGFR difference up to 6 mths later, suggesting IV contrast is not linked w/long-term renal injury
3
15
74
The
@JAMANetwork
welcomes
@sharon_inouye
, the new Editor in Chief of
@JAMAInternalMed
. Dr. Inouye comes to us from
@harvardmed
. We are thrilled to have her lead JAMA Internal Medicine starting July 1.
2
13
72
Did You Know? New studies indicate that the gut
#microbiome
can influence the effectiveness of
#cancer
immunotherapy and manipulating gut bacteria might expand the population of patients who benefit from treatment
#PD1Inhibitors
3
53
71
Diabetic Foot Guidelines: Test patients w
#diabetes
for peripheral neuropathy using the Semmes-Weinstein test
0
46
71
Continuing ACE-I/ARB in patients with declining kidney function may provide cardiovascular and survival benefits without excessive harm of ESKD.
3
33
71
Only 1 of 159 medical students correctly performed all 11 elements in a BP check challenge with simulated patients
8
84
71
Doctors who receive opioid-related
#marketing
from pharmaceutical companies prescribe more
#opioids
the next year, shows new research from
@The_BMC
and
@DrScottHadland
1
62
67
How to mitigate burnout in physicians? A meta-analysis of interventions builds the evidence.
0
100
69
To decrease antibiotic treatment related to asymptomatic bacteriuria, hospitals should prioritize reducing unnecessary urine cultures (ie, diagnostic stewardship).
0
30
68
Mediterranean diet w olive oil or
#nuts
associated w improved cognitive function
http://t.co/ASFq1XYfcs
#rct
http://t.co/Xnp8hGReOa
4
143
67
Diabetic Foot Guidelines: Test patients w
#diabetes
for peripheral neuropathy using the Semmes-Weinstein test
2
64
69
2017 Hypertension Guideline
Begin meds if
- Clinical CVD or
- 10y ASCVD risk >= 10% AND SBP >=130 mm Hg / DBP >= 80 mm Hg or
- 10y ASCVD risk >= 10% AND SBP >=140 mm Hg / DBP >= 90 mm Hg or
1st-line meds =
- Thiazides
- CCBs
- ACE inhibitors or ARBs
2
40
66
Hypertension treatment thresholds in the general population:
Age < 50 <120/80
Age 50-74 <130
Age >= 75 <140
1
96
69
Largest
#smoking
cessation clinical trial (EAGLES) found anti-smoking medications (
#varenicline
,
#bupropion
, and nicotine patch) don't increase risk of serious
#CV
events in a general population of smokers
0
47
67
In-hospital exercise can reverse the functional and cognitive impairment associated with acute hospitalization in older adults. Watch this
#video
or visit to learn more.
1
55
66
Reducing inappropriate
#polypharmacy
: the process of deprescribing
http://t.co/URgDjMTtLN
http://t.co/xxnEI85kdx
11
103
64
Fewer internal medicine residents nationally are planning a career in general internal medicine than 2011. Based on 2019-2021 in-training exam data, less than 10% of IM residents are now reporting GIM career plans.
3
19
64
Review of Antimicrobial Resistance by Tony Fauci and colleagues
0
61
66
Controlled Interventions to Reduce Burnout in Physicians
0
63
65
Proton pump inhibitor use is associated with 20-50% higher risk of chronic
#kidney
disease.
4
114
65
Urgency is not an emergency. Using IV drugs for
#hypertensive
urgency can lead to more harm than good
#highvaluecare
via researchers at
@IcahnMountSinai
1
45
63
Older women taking 4,400 steps/day have lower mortality than those taking 2,700; "more is better" up to 7,500 steps/day, when mortality rates level
#ACSM19
0
51
64
Screening
#mammography
detects additional small
#cancers
w/o reduction of death
http://t.co/17BpKFZhH8
#lessismore
http://t.co/HygCGd6rvB
1
68
62
Effect of moderate to vigorous physical activity on all-cause mortality
http://t.co/WU8pUG2Wxb
http://t.co/U1MIFB7kVO
4
93
59
Evidence-Based Guidelines to Eliminate Repetitive Laboratory Testing
2
47
60
Clinical trial shows moderate exercise is effective for nonalcoholic fatty liver disease.
0
50
58