JAMA Network Open
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JAMA Network Open is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.
Chicago, IL
Joined April 2017
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1 in 3 academic physicians report they are considering leaving their institution within 2 years. Burnout and lack of professional fulfillment were associated with intention to leave; a comprehensive approach will be needed to reduce physician turnover.
22
256
708
First-generation medical students experience disproportionate adversity and inadequate institutional support within medical education, forcing over-reliance on grit and resilience as survival strategies.
@catiehavemann
9
203
455
In this meta-analysis of
#COVID19
vaccine trials, adverse events in placebo arms ("nocebo responses") accounted for 76% of systemic adverse events after the first COVID-19 vaccine dose, and for 52% after the second dose.
13
76
201
A
@Wiki_Guidelines
Consensus Statement: For adults with infective endocarditis, oral transitional therapy was at least as effective as IV-only therapy.
@DrEmilyMcD
@DrToddLee
4
69
144
In this cross-sectional study, oncology drugs were 40-times more likely to be deemed cost effective when the study was funded by pharmaceutical companies compared with no funding.
5
50
143
Cross-sectional study comparing Medicaid &
#ACA
Marketplace finds fewer ED visits & more office visits in Marketplace, no clear quality advantage. Marketplace costs 80% more overall, with 10x higher out-of-pocket spending.
@Prof_HeidiAllen
@HarvardHPM
0
44
129
This study found that written exposure therapy (
#WET
) is non-inferior to cognitive processing therapy (
#CPT
) for
#PTSD
. WET was also associated with fewer treatment dropouts than CPT.
@VA_PTSD_Info
@strongstar_ptsd
0
37
111
RCT: Eating 10 min longer during family mealtimes increased fruit and vegetable intake but not dessert or bread consumption. Longer family meals are a simple tool that may improve children’s health.
5
33
113
In qualitative interviews, Black patients with serious illness reported experiencing racism in clinical settings, often through epistemic injustice, that was associated with medical mistrust and poor patient-clinician communication.
0
55
107
Case analysis of >3.9 mil COVID cases in California found that pediatric vaccination averted >375,000 cases of COVID-19 and 270 hospitalizations in children 6mo-15yrs in the 4 to 7 months following vaccine availability.
@JenniferR_Head
@Justin_Remais
0
51
100
This cohort study in New Delhi found 2.5% reinfection in health care workers (HCWs). The BBV152 (Covaxin) 2-dose effectiveness against reinfection was 86%. Findings suggest infected HCWs should receive complete vaccine doses to prevent future infections.
8
48
96
Only 8% of oncology clinical trials involve surgical interventions. Surgery can be critical to cancer care. There is a need for more surgeons in cooperative research groups and increased NCI funding to study surgical interventions.
2
27
87
In a large nationwide cohort of 996,300 Danish-born females, there was no association between HPV vaccination and primary ovarian insufficiency.
@anders_hviid
0
20
79
Fathers of preterm infants reported less stress in Family Integrated Neonatal Care compared to standard care. Supporting fathers' participation in neonatal care is associated with improvements in fathers' mental health.
4
40
80
Among vaccinated recipients of allogenic stem cell transplants, the incidence of
#COVID19
infection was higher during Omicron vs Delta waves; most infections were mild, with 3 hospitalizations and 1 death out of 211 patients at one center in France.
2
28
77
Women and parents report greater burden from early AM/late PM multi-disciplinary tumor boards. Radiologists, pathologists, those with ≥2 kids, or attending ≥3 hrs/wk of tumor boards report greater overall burden.
@_katelynatkins
@CedarsSinai
0
29
73
Eli Perencevich MD, MS, has been named Editor in Chief of
@JAMANetworkOpen
. Dr Perencevich is a professor of internal medicine and epidemiology at
@IowaMed
and is a founding Associate Editor of JAMA Network Open.
He will assume the position July 1.
174
8
74
This first of its kind study shines a light on a troubling problem - women physicians are underrepresented among perspective-type journal articles in top pediatrics journals. Read more from
@JulieSilverMD
:
#WomenInMedicine
1
46
72
Cohort study finds excess mortality during the early phase of the
#COVID19
outbreak in New York City was comparable to that observed during the peak of the 1918 H1N1 pandemic.
@jeremyfaust
@CarlosdelRio7
2
46
67
Every $1 invested in the New York City
#COVID19
vaccination campaign yielded an estimated $10.19 in cost savings from lower infection and mortality rates, fewer productivity losses, and averted health care use.
@suhas_gondi
@davechokshi
@Alison_Galvani
2
33
66
Cohort study finds 33% of mildly ill individuals reported persistent
#COVID19
symptoms at an average of 6 months after their acute infection.
@HelenChuMD
@UWMedicine
1
26
64
When physicians attend to emotions and then stop to allow a family to respond, families are able to express their emotions and provide valuable information. Learn more in this
#Pediatrics
Original Investigation:
6
46
61
Cross-sectional study finds few oncology clinical trials assess QoL until death which is important particularly when gains in OS are marginal.
@VPrasadMDMPH
3
41
64
40% of low income households with young children "churn" off SNAP benefits due to missed administrative deadlines at recertification, despite being eligible. Streamlining administrative processes needed.
#OAResearch
0
32
60
Health care worker (HCW)-collected throat specimens may have higher sensitivity than HCW-collected nasal specimens for COVID-19 rapid antigen testing. Self-collected specimen sensitivity may improve by combining nasal & throat specimens.
1
31
61
Tax policy is an important, modifiable social determinant of health. Increased state-level tax revenue and increased tax progressivity (ie, higher taxes for wealthier individuals) were both associated with decreased infant mortality in the US, 1996-2019.
1
41
58
21% of medical journal articles cited by GPT-4 were found to be fake; GPT-3.5 cited an estimated 98% fake articles. Narrower topics had more fake articles than broader topics. Despite its promise, ChatGPT is currently not a reliable source of medical data.
2
27
57
Only 13-14% of
@usnews
-ranked medical schools give faculty 12-wks parental leave at full pay; lower rates for adoption/foster leave. Inadequate parental leave contributes to physician workforce attrition &
#BurnOut
.
@JessSlostadMD
@nedalai
@ShikhaJainMD
3
26
59
Integrating buprenorphine and harm reduction kits into primary care could improve clinical outcomes, and be cost-effective to health systems.
0
21
59
Case series observing 9 emergency medicine residents shows that 50% of ROS and PE content of physician documentation is inaccurate, likely to fulfill
@CMSGov
charting requirements.
@carlberdahl
(on
#JNOLive
Tuesday at 3 pm cst)
7
28
57
Employer-mandated switching of people with
#diabetes
to high-deductible health plans is linked to higher rates severe hypoglycemia and hyperglycemia, especially for low-income and non-White employees.
@RozalinaMD
@DavidHJiang
@NIDDKgov
@MayoClinic
1
16
55
The introduction of
#ChildTaxCredit
advanced payments in July 2021 was associated with a 26% drop in
#FoodInsufficiency
among households with children, in a study using
@uscensusbureau
data.
@shaferpr
@katie_mo_
@stephanieedc
@AllisonBovell
@juliaraifman
1
30
52
Cohort study finds men interrupt more than women at internal medicine residency teaching conferences, more so with a male faculty discussant.
@amrapalimaitra
@MariaYialamas
@HarvardMed
@brighamwomens
0
10
53
This cohort study found no association in positivity rates among health care workers who wore medical masks vs respirator masks in routine patient care suggesting that medical masks protected HCWs from acquiring
#COVID19
1
24
51
For infants born at 22-23 weeks, antenatal steroids at 21-22 weeks is associated with better survival in this
@NICHD_NIH
Neonatal Research Network study.
#neoEBM
#OAResearch
1
17
52
This model-based analysis estimated "on-ramps" and "off-ramps" for unmasking elementary students, using readily available data (case counts and vaccination rates). Appropriate metrics for unmasking will depend on community goals.
@SalomonJA
2
27
49
The
#COVID19
vaccine rollout in the US saved an estimated 240,000 lives and averted 1.13 million hospitalizations from the start of vaccination campaign to June 30, 2021.
@Alison_Galvani
@Pratha_Sah
@MeaganCFitz
@abhiganit
5
25
50
Does repeated flu vaccination reduce protection in children? A 3-year study says no and protection against H3N2 was increased by repeated vaccination.
1
39
49
Qualitative study describes female academic surgeons' perceptions of factors promoting and hindering their professional success.
@UMichSurgery
@JAMASurgery
#JNOVA50
cc:
@mdaware
1
31
49
Prostate safety is a concern of men considering testosterone treatment. In the TRAVERSE Trial, a large testosterone RCT in men with hypogonadism, rates of prostate cancer and other prostate events were low and did not differ vs placebo.
2
20
49
Amid a changing landscape of public charge rules, nearly 1 in 6 low-income immigrant adults avoided public programs out of fear it would negatively impact immigration status, leading to delayed medical care.
@UCLACHPR
@NinezPonce
@UCLAFSPH
@CalEndow
2
39
46
Open Access from the JAMA Network:
The Burden of Cardiovascular Diseases Among US States, 1990-2016
#cardiology
1
29
47
Ultra-Restrictive Opioid Prescription Protocol (
#UROPP
): radical decrease in postoperative opioid use with no changes in pain scores & opioid refills.
12
31
46
Cohort study finds the
#ACA
was associated with 2 million fewer adults experiencing catastrophic health expenditures each year; 11 million, including 6 million privately insured, experience catastrophic spending annually.
@chasliu
@krchhabra
@DrJohnScott
0
25
47
Comparative effectiveness study with 41k insured people w OUD finds only buprenorphine/methadone associated with reduced
#overdose
at 3 & 12 mos; longer treatment assoc w lowest OD risk
#VisualAbstract
@DrSarahWakeman
@MDaware
0
30
48
Commentary: Although many believe observational, real-world data will someday fill the gaps, for the time being, randomization remains the reference standard in cancer research.
@RahulBanerjeeMD
@VPrasadMDMPH
1
20
48
RCT: Eating 10 min longer during family mealtimes increased fruit and vegetable intake but not dessert or bread consumption. Longer family meals are a simple tool that may improve children’s health.
0
18
48
Structural racism in the form of historical housing discrimination known as “redlining” is associated with higher stroke prevalence in NYC communities, even after controlling for classic stroke risk factors and other social determinants of health.
0
21
45
This cohort study found that after the
#MuslimBan
, missed primary care appointments and emergency department visits increased among people from Muslim-majority countries living in Minneapolis-St. Paul.
0
30
43
In this cohort study there was no evidence to support an association between a higher number of lumbar segments with radiographic changes and more severe back pain–related disability cross-sectionally or over time.
4
19
47
Modeling study by
@CCDD_HSPH
supports frequent screening testing to control nursing home outbreaks of
#COVID19
and finds staffing based on infection history can protect residents.
@ingaholmdahl
@rebeccajk13
@jameshay218
Caroline Buckee
@michaelmina_lab
1
23
47
Meta-analysis: 94% of patients with atraumatic altered mental status received a noncontrast CT head, with an average yield of 11% which varied by setting: 18% in ED patients, 12% of ICU patients, and 3% of general inpatients had positive findings on CT.
7
12
46
Editorial: Current events surrounding racially motivated police brutality highlight that journals must focus on the effects of structural racism on the care of Black, Hispanic, indigenous, and other people of color, including interventions.
@GbengaOgedegbe
0
20
45
This phase 3 randomized controlled trial demonstrated that a new macrophage-regulating drug significantly improved the incidence of complete wound closure in treating chronic diabetic foot ulcers.
15
28
39
Prognostic study finds modeling real-time, dynamic changes in suicidal thoughts improves prediction of suicide attempts post-psychiatric hospitalization.
@ShirleyBWang
@mk_nock
@NockLabHarvard
0
8
42
Gender-affirming surgery increased substantially among US adults from 2016 to 2019 and declined slightly in 2020. Breast and chest surgeries were the most common procedures performed and genital reconstruction was more common on older individuals.
0
8
44
High doses of oral CBD can exacerbate THC’s effects through inhibition of THC metabolism, leading to stronger drug effects. Cannabis users, clinicians, and regulators stakeholders must understand the potential risk of drug interactions.
2
25
40
Subgroup analyses are common in oncology trials. However, a new study of 379 phase III trials suggests most claims for differential treatment effects in subgroup analyses have low credibility.
@MDAndersonNews
@AlexSherryMD
@PavlosMsaouel
@PavlosMsaouel
0
15
42
SSRI antidepressant use may reduce mortality from
#COVID19
,
@Cerner
EHR study found those who had taken fluoxetine had a 28% ⬇️ in the relative risk of death
@msirota84
@NimaAghaeepour
@oskotsky
@AliceTang_mstp
@ivana_mmari
@tomiko22
@SirotaLab
@UCSF_BCHSI
0
18
39
For patients with limited English proficiency undergoing surgery, interpreter use is low and only 12% of patients received language-concordant discharge forms, which provide critical opportunities to tangibly enhance care plans’ quality & understanding.
1
11
39
Many firearm owners store firearms unlocked; those who lock their firearms most often use gun safes. Concerns about access speed often keep firearm owners from using locks, whereas concerns about child access may increase the odds they will use a lock.
0
29
38
In this cohort study of adult daily cigarette smokers with no plans to ever quit smoking, those who took up daily e-cigarette use experienced 8-fold greater odds of discontinuation versus those who did not use e-cigarettes.
1
20
37
Racial, gender, and socioeconomic inequities are present in access to SGLT2i, which if unaddressed, may widen well-documented disparities in renal and cardiovascular outcomes in the US
@eberly_lauren
@sri_adu
@pennmedicine
@PennLDI
@AmakaEMD
0
12
37
IV sodium thiosulphate (STS) treatment is not associated with improvements in skin lesions and survival in patients with calciphylaxis with chronic kidney disease in this meta-analysis of observational studies.
1
24
37
What are the core competencies in evidence-based practice (
#EBP
) that health professionals should meet? Visit to view the findings.
2
25
36
Cross-sectional study finds
#NIH
funding not associated with more female faculty; increases in female faculty was modest vs increases in women’s matriculation in medical schools.
@ebmalinzakMD
@ZoinksScoob78
@mswami001
@DukeMedSchool
0
16
37
Older vs younger patients with cancer (≥70 vs <70) enroll in
#NCI
clinical trials at similar rates when screened and offered trial entry in the community setting, where 80% of older patients receive their
#GeriOnc
care.
@minasedrakmd
@WilliamDale_MD
#OAR
1
14
36
This consensus statement & systematic review uses a WikiGuidelines methodology for clinical guideline development (precluding recommendations based on low-quality data/opinion), addressing 7 questions regarding osteomyelitis management.
@BradSpellberg
0
19
36
Quality improvement study from
@MSFTResearch
Project InnerEye team uses
#DeepLearning
to maintain clinical accuracy and reduce manual contouring time in radiotherapy treatment-CT scan mark up for radiotherapy in head & heck & prostate cancers.
@ozanoktay_
0
12
36
Mortality associated with adverse effects of medical treatment decreased 21.4% from 1990-2016
#patientsafety
0
30
34
Half of people who disenrolled from Minnesota Medicaid in 2018 or early 2019 had no observable coverage 6 months later, and a large share returned to Medicaid within a year, suggesting many were still eligible or had very short-term changes in eligibility.
0
10
36
Vitamin D supplementation may be less helpful at increasing circulating vitamin D concentration among individuals with higher BMI.
5
13
35
The impact of PRISM resilience coaching seems to last: Cancer survivors who received it reported sustained improvements in hope and quality of life 2 years later.
@AbbyRosenbergMD
@JohnMSalsmanPhD
@seattlechildren
@UWMedicine
@UWPeds
#hapc
#pedpc
#AYACSM
0
14
35
Cross-sectional study finds states with legal recreational marijuana had fewer cases of e-cig/vaping associated lung injury
#EVALI
.
@aaronecarroll
@ajhollingsworth
@AshleyCBradford
@coady_wing
#VisualAbstract
4
22
34
Pooled results from
@rheum_covid
,
@SecureIBD
, and
@PsoProtect
, representing >6000 patients with immune-mediated inflammatory disease and
#COVID19
, support TNFi monotherapy use during the pandemic.
@IzadiZara
@EJBrenner_MD
@JYazdanyMD
@MichaelKappel12
0
15
34
Only 0.2% of children 6-17-years-old with
#COVID19
in Sweden were diagnosed with
#LongCovid
, more often in girls, those hospitalized for COVID or with comorbidities, and those whose parents had post-COVID conditions, suggesting a possible genetic link.
17
11
34
This study finds that the first two overdose prevention centers to open in the US with government support were not associated with changes to neighborhood crime and disorder. Overdose prevention centers have a long track record of saving lives.
0
19
33
Liver metastases was associated with poorer survival (vs non-liver metastases) in patients with mismatch repair-deficient metastatic colorectal cancer treated with first-line pembrolizumab.
0
15
33
Systematic review & meta-analysis finds steroid injections & physical therapy are associated with the best outcomes for frozen shoulder.
@tendonglasgow
3
17
33
Cohort study finds racial/ethnic, gender, age, language & SES differences in accessing telemedicine for primary care and specialty ambulatory care during
#COVID19
; differences may compound existing inequities in care.
@eberly_lauren
@sri_adu
@PennMedicine
0
18
33
The surveillance rate for low-risk
#ProstateCancer
has risen from 27% to 60%, 2014-2021, but overtreatment remains common, with substantial local variation.
@dr_coops
@dannymak
#pcsm
@amerurological
Quality AQUA Registry
0
10
31
Nine of 10 sports supplements listing novel botanical ingredients were inaccurate when tested, and 12% contained
@US_FDA
-prohibited stimulants.
1
15
31
Living donor kidney transplants from donors biologically related to their recipients have a higher rate of allograft failure than those from unrelated donors after accounting for degree of HLA mismatching.
@SAHusainMD
@SumitMohanMD
@columbiakidney
3
8
31
Patient-level economic analysis found that icosapent ethyl to be cost-effective in the US healthcare sector at common willingness-to-pay thresholds for high-risk patients with hypertriglyceridemia.
0
12
31
Intelligence, cognitive flexibility and academic performance improved following a 20-week RCT based on aerobic + resistance training among children with overweight or obesity.
@ortegaporcel
@profithugr
@canalUGR
and collaborators.
#OpenAccess
#Research
0
18
31
Study found that among countries hosting
#COVID19
vaccine trials, high-income countries received proportionately more doses than their middle- and low-income counterparts, reflecting disparities in vaccine access.
@reshmagar
@jsross119
@millerbioethics
0
13
31
Women who benefited from the Brazilian Cash Transfer Program had an 18% lower risk of maternal death, reinforcing the great potential of these programs to improve maternal survival.
0
9
29
This cohort study in Scotland found that labor epidural analgesia was not independently associated with adverse neonatal or childhood development outcomes.
0
12
28
Comparative effectiveness study uses
#COVID19
data from Wuhan and Guangzhou to estimate need for early & strict disease control strategies in US cities to mitigate the demand for inpatient and ICU beds.
@ruoranepi
@cmyeaton
@megan_b_murray
@mlipsitch
0
13
29
Cross-sectional study finds < 2% of OB-GYNs who treat Medicaid enrollees have X-waiver training to prescribe buprenorphine; those who are are more likely to work in suburban counties.
@MaxJordan_N
@Eugenia_South
@zacharymeisel
3
6
30
This systematic review and meta-analysis including 15,000 infants estimates rates of bacteremia and meningitis are low in febrile infants; nearly half as low in the second month of life
@JAMAPediatrics
#JNOVA50
cc:
@mdaware
3
26
30
Adjuvant stereotactic radiosurgery for resected brain metastases within 22-30 days minimizes both local failure and post-treatment radiation effects.
@MSKNeurosurgery
@Dr_N_Moss
@BrainMets_MSK
@evanbanderMD
@MSK_RadOnc
@MSKBiostats
@telahmadieh
0
15
29
RCT: The dural-puncture epidural technique provided a faster onset and improved block quality for cesarean delivery when used for epidural extension, vs the standard epidural technique.
1
15
29