Tobias Janowitz
@JanowitzTobias
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Scientist and Medical Oncologist, committed to understanding the whole body response to disease/cancer @cshl
Cold Spring Harbor, NY
Joined January 2019
"Why do I no longer enjoy my favorite food and activities?" - an important question from our patients with cancer and cachexia! Cancer is a disease of the whole body, including the brain. @KepecsLab @Pignatelli_Lab @miriamferrer95 @CancerGrand @CSHL .
science.org
Cachexia, a severe wasting syndrome associated with inflammatory conditions, often leads to multiorgan failure and death. Patients with cachexia experience extreme fatigue, apathy, and clinical...
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Congratulations, Ying, both on the discovery work and excellent coordination of the team effort across species.
Excited to share our full-body single-nucleus transcriptomic survey of a fly cancer cachexia model, revealing organism-wide dysregulation during disease progression. @eze_dantas @miriamferrer95 @MarcusDGon @JanowitzTobias @PerrimonLab @CancerGrand
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Thank you to @HassalLee for her dedicated work. We hope the work will make a contribution to clinical trial and health care development.
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RT @HassalLee: Simulating commuting populations to high-volume cancer trial sites and all hospitals nationwide in the US to strategize #Hea….
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Thank you to my outstanding PhD student @KleemanSam for combining analyses of large clinical data sets with experimental validation work to establish Cystatin C as an immune modulatory glucocorticoid response gene. @dufourlab @HannahVMeyer .
cell.com
Kleeman et al. reveal a connection between cystatin C, a blood marker often used to measure kidney function, and glucocorticoid signaling. The authors further demonstrate that cystatin C plays a role...
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RT @KleemanSam: Cystatin C: not just a biomarker for kidney function. I am incredibly excited to share my 1st first-author publication of….
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Thank you to my outstanding PhD student Miriam Ferrer @miriamferrer95 for driving this discovery project and thank you for the input, support, and feedback @MarcusDGon @EileenWhitePhD @CancerGrand @TheMarkFdn @PitarresiLab @laird_barry @FrezzaLab et al.
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RT @miriamferrer95: 1/4 I am delighted to share the outcome of my main PhD project now published at @Cell_Metabolism. We studied the effect….
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Thanks for the positive comments and feedback on our review on cachexia @miriamferrer95 @CancerGrand Very happy about the broad readership. Cachexia: A systemic consequence of progressive, unresolved disease
cell.com
Cachexia is a common systemic wasting condition with high morbidity and mortality associated with many diseases, including cancers and infections. This review summarizes and connects molecular...
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RT @miriamferrer95: 1/3 Very happy to see our review on cachexia as a progressive systemic condition published in @CellCellPress - Grateful….
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RT @A__Furlan: you crave junk food? here is why! Thanks and congrats to all co-authors: @Sarsaparillla @Mr_Beto_Corona @EvaGablenz @Jackie_….
nature.com
Nature Neuroscience - Furlan et al. report that neurotensin-expressing neurons in the IPAC encode preference for unhealthy energy-dense foods and drive hedonic eating. Thus, inhibition of these...
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RT @emmakurz: (1/n) I am truly delighted (and nervous) to share with the world the culmination of 5 years of work, finally out today in @Ca….
cell.com
Kurz. et al. discover that aerobic exercise slows pancreatic cancer growth in mice through activation of the immune system, particularly CD8+ T cells. The beneficial effects of exercise can be...
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RT @miriamferrer95: @emmakurz and Dafna Bar-Sagi link exercise-induced IL-15 signaling to improved anti-cancer immunity @Cancer_Cell Congra….
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Grateful for an amazing team to tackle cachexia. Thanks Cancer Grand Challenges team! @CancerGrand @theNCI @MarcusDGon @EileenWhitePhD @OMaddocks @BiffiGiulia @StephenORahilly @theayreslab @MariamJHanjani @realTonyHui @kmustian @DrR_DUNNE @PerrimonLab @LUNGevity @acmoorephd
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RT @MarcusDGon: In all our projects, we will incorporate the patient perspective via our excellent advocacy team @LUNGevity @ICPVtweets @ac….
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RT @MarcusDGon: Thank you @CancerGrand and @theNCI for the opportunity to tackle #cachexia with an amazing team @EileenWhitePhD @JanowitzTo….
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RT @KevinJTraceyMD: Thank you @carolmassar and @timsteno @BloombergRadio for hosting me today to discuss our recent Phase 2 study of famoti….
gut.bmj.com
Objective We assessed whether famotidine improved inflammation and symptomatic recovery in outpatients with mild to moderate COVID-19. Design Randomised, double-blind, placebo-controlled, fully...
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Congratulations Miriam and thank you to you and Mirco for your excellent work! Thanks to all co-authors @timotheus_halim @FrezzaLab.
I’m excited to share our recent work on the role of neutrophils in host metabolism during cancer progression to cachexia. @MDPIOpenAccess
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RT @Sandeep_N: I am excited to share the results of our recent randomized placebo, controlled, double blind control trial. We tested if hig….
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