PitarresiPhD
@PitarresiLab
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Jason R. Pitarresi. Father. Studying pancreatic cancer, cellular plasticity/metastasis, and tumor-host interactions. @pitarresilab.bsky.social
Joined February 2021
I'm excited to share the lab’s new paper on PDAC-associated cachexia on bioRxiv today, led by star postdoc @Nikita2106. Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis. A 🧵 below, if you're interested.
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RT @Aiims1742: New @iScience_CP paper by @NinaSteele17 @Pasca_Lab .Primary and metastatic cellular landscapes in human #PancreaticCancer .h….
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RT @washingtonpost: Harvard, the nation’s oldest university, is facing off in court against the president today in a legal showdown, the ou….
washingtonpost.com
Harvard called the government’s rationale for cutting billions of dollars in federal funding illegal and “cooked up”
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RT @OSUGeneTherapy: 🧬We are thrilled to announce that Bin Liu, PhD (@BinLiu49077152) has joined the Gene Therapy Institute! Bin completed h….
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RT @Marcus_Ruscetti: It finally happened! Congrats to @katcmurph and @peura_jessica on officially receiving their F31 fellowships! Very pro….
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RT @Marcus_Ruscetti: Congrats to @katcmurph from our lab and @peura_jessica from @PitarresiLab on their great F31 application scores! Very….
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Awesome new preprint from Christine Chio's group @Chiolaboratory on the role of Iron-regulating signaling in cancer cachexia! A new mechanism fueling adipose browning in cachexia.
biorxiv.org
The browning and atrophy of white adipose tissue (WAT) are early events in cachexia, a lethal metabolic disorder affecting nearly half of cancer patients, including those with pancreatic ductal...
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RT @BenStanger01: 50% OFF From One Cell: A Journey into Life's Origins and the Future of Medicine - through Aug 11!
audiobooks.com
Each of us began life as a single cell. From this humble origin, we embarked on a risky journey fraught with opportunities for disaster. Yet, amazingly, we reached our destination intact, emerging as...
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Congrats to Calvin in the lab for winning a travel award for the AAI Advanced Course! He's leading the tumor immunology efforts in the lab and I'm excited to see what he learns at the workshop!. 🙏 Grateful to the AAI for supporting trainees during these tough financial times!
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RT @Aiims1742: A jobs bonanza from @michiganstateu @HenryFordHealth hiring TEN cancer researchers! .Applicants focu….
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NOA!!. 🚨 Congrats to @peura_jessica in the lab for getting her NCI F31 notice of award today!! 🚨. With the NIH slowdowns, this has been quite the journey, but I'm happy to see some NOAs coming through for the trainees!. @UMassChan
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RT @Aiims1742: New @AGA_Gastro study by Suresh Chari @MDAndersonNews: .The 1st prospective study to estimate the risk of #PancreaticCancer….
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RT @DrJashDatta: 🔥🚨New from #DattaLab @SylvesterCancer in Cancer Immunology Immunotherapy @SpringerNature:.We report a cell-specific nanoen….
link.springer.com
Cancer Immunology, Immunotherapy - Pancreatic ductal adenocarcinoma (PDAC) is characterized by intratumoral abundance of neutrophilic/polymorphonuclear myeloid-derived suppressor cells (PMN-MDSC)...
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RT @Dev_Cell: Online now: Conserved signals control self-organization and symmetry breaking of murine bilayered epithelia during developmen….
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Excited to present at this fantastic meeting!.
The first morning of the @CancerCachexia Conference will be focused on how the tumor microenvironment and metastasis drive, and impact, cachexia from basic science and clinical perspectives. The early-bird registration deadline is June 30th:
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RT @MuzumdarLab: 1/🚨 New preprint out!🚨.We uncovered that #PI3K-driven wild-type RAS activation bypasses #KRAS inhibition in pancreatic ade….
biorxiv.org
Despite the availability of RAS inhibitors and the dependence of >90% of pancreatic ductal adenocarcinomas (PDAC) on oncogenic KRAS mutations, resistance to KRAS inhibition remains a serious obstac...
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RT @CedricBlanpain: I am delighted to share our new study uncovering the role of innate immunity in regulating cell plasticity and reprogra….
nature.com
Nature Cancer - Blanpain and colleagues delineate lineage reprogramming following PTEN deletion in different prostate cancer-originating cells, demonstrating that in basal cells the NF-κB...
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RT @ChadPecot: Now in @Cancer_Cell our group reports the development of a first-in-class EGFR-directed KRAS G12V selective inhibitor. KRA….
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RT @MaxReichertMD: 🤩Super excited our branched #PancreaticCancer #Organoids to capture tumour heterogeneity made it on the cover of @natBME….
nature.com
A 3D collagen system is used to generate a phenotypic landscape of mouse and human pancreatic cancer organoids, uncovering heterogeneity of the disease. Most...
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RT @Nature: A US judge has ordered hundreds of terminated research projects at the NIH to be reinstated, calling the processes that led to….
nature.com
Nature - The decision means that the US biomedical agency has to restore funding to hundreds of research projects, but the government is likely to appeal.
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