Cancer Cachexia: Liver Identified as Active Driver of Body Wasting. 👉 Up to half of all #cancer patients experience #cachexia – a severe syndrome marked by dramatic loss of muscle, fat, and even heart tissue. It is a major cause of therapy resistance,

Cancer associated fibroblasts (CAFs) have been implicated in the pathogenesis of tumor #cachexia through their ability to modulate inflammation, metabolic reprogramming, and immune responses. Learn more in this new review! 📚.

＼心不全で入院症例／（投稿許可あり）. 🧐 心臓悪液質（Cardiac Cachexia）.・下腿の骨格筋量と脂肪の減少.・指輪っかテスト陽性（smaller）.・男性で下腿毛（すね毛）なし.・本例は重症の心不全（Stage D）

50-year-old female with iron deficiency anemia and cachexia. Likely diagnosis?

筋肉が減るのは運動不足だけ？. J Cachexia Sarcopenia Muscleの最新レビューでは、実は、体内の“脂肪”が筋肉を壊すスイッチになっているかもしれないことが示唆されています。. サルコペニアと脂肪の意外な関係を解説しています↓.

Recent study at @NImmunology posits VDR as a key metabolic switch during weaning. It shows vitamin D receptor (VDR) disrupts liver glycogenolysis, triggers hypoglycemia, fat wasting and cachexia, but Ca/P- rich diets rescue energy balance. Read more:

We are delighted to announce the outstanding speakers for two more scientific sessions at the 2025 @CancerCachexia Conference. Don't miss the registration deadline of August 1!

New! Online now: MIF-ACKR3 causes irreversible fat loss by impairing adipogenesis in cancer cachexia

I'm excited to share the lab’s new paper on PDAC-associated cachexia on bioRxiv today, led by star postdoc @Nikita2106. Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis. A 🧵 below, if you're interested.

Cancer-associated Cachexia is a lethal metabolic syndrome marked by systemic inflammation, CNS appetite dysregulation, & muscle/fat loss—better characterized with imaging. Prevalent in cancers like pancreatic/lung, it's linked to IL-6, GDF-15, & tumor-driven energy drain. Trials

Great Keystone meeting in Ireland! #cancer #cachexia #obesity #diet #metabolism #microbiome #immunity.

📢New from our #CANCAN team: We report outcomes from a multidisciplinary cachexia clinic embedded in endocrinology. Multimodal care stabilized weight loss and improved function in cancer patients. #cachexia #oncology #endocrinology #metabolism

Now online! Functional liver genomics identifies hepatokines promoting wasting in cancer cachexia

Tomorrow at the Muscle Biology and Cachexia Conference, Mamata Chaudhari, a graduate student from Dr. Baba’s laboratory, will present work on skeletal muscle scavenging of carbonyls in heart failure and how this may improve exercise capacity.

Functional liver genomics identifies hepatokines promoting wasting in cancer cachexia: Cell

Nutrition, cachexia, and supportive care aren't extra, they're essential!!!.This @myESMO preceptorship isn't just education, it's about improving survival, quality of life, and daily oncology practice!!! .#Oncology #SupportiveCare #ESMO25 #cancer #nutrition #cachexia.@myESMO.

Niacin for mitochondrial myopathy and counteracting cancer cachexia

Papers on cancer metabolism - April 2025 . Metabolism of glucose and other sugars, amino acids, lipids, starvation responses and nutrient sensing, immunometabolism of cancer, cachexia . MetaboList.

Functional liver genomics identifies hepatokines promoting wasting in #cancer cachexia @CellPressNews