Rout Lab
@RoutLab_RU
Followers
227
Following
153
Media
17
Statuses
130
Lab of Michael Rout @RockefellerUniv | NCDIR member (@IntActOme) | Interactomics, NPCs, nuclear transport & making nanobodies https://t.co/5nEKSfKwZe
Rockefeller University, NYC
Joined March 2023
Incredibly excited to share this paper with the community! Congratulations authors including @DrMartyTaylor, @dfhoyosg, @ArthurZalevsky, the amazing team at @rome_tx led by Donna Romero, @macro_momo, @bengrbm, Eddy Arnold @RutgersU, Matthias Götte @UAlberta, & @KathleenHBurns.
So excited to share our story revealing structures, functions and adaptations of the human LINE-1 retrotransposon, an ancient genetic parasite that has written 1/3 of the human genome and is implicated in cancer, aging, & autoimmunity. Now out in @Nature
0
6
15
Congratulations all authors, particularly @dgvjayS @neeleshsoni03 @JoshHutchings94 who led this heroic effort on the first molecular model of the NPC nuclear basket. Out now in @CellCellPress.
Our work on the architecture and model of the #NuclearBasket is now out @CellCellPress. @HHMINews, @IntActOme #NPC #teamtomo .A short tweetorial follows
0
2
12
Amazing! Congrats Steve.
Excited to share our short review on the challenges of applying single-particle cryo-EM to RNA structures and some of the methods developed to overcome them. Hope you find it useful!
1
0
2
RT @neeleshsoni03: From preprint to journal. Our nuclear gatekeepers have successfully unlocked the gates to Cell (Journal) .
0
18
0
👀👀👀.
In a great collaboration with @HummerLab and the Kräusslich lab, @jpkreysing, @MaziarHeidari1, @VojtechZila and others tackle what happens when HIV capsid goes through an NPC. Instead of the NPC cracking the capsid, the capsid appears to crack the NPC (@MPIbp @CiidHeidelberg).
0
0
0
RT @Beck_Laboratory: In a great collaboration with @HummerLab and the Kräusslich lab, @jpkreysing, @MaziarHeidari1, @VojtechZila and others….
0
31
0
0
2
17
RT @TheVillaLab: It cannot be done, they said. It's too flexible, they said. 😁.#NPC #teamtomo #integrativemodelin….
0
119
0
RT @RockefellerUniv: Rockefeller's @SanfordMSimon featured in @guardian for his work on fibrolamellar carcinoma, a rare liver cancer:. “The….
0
5
0
👀👀👀.
Collaborative work led by @svenklumpe resolves the structure of a mobile genetic element inside of developing tissue. Together with @juliusbrennecke @BriggsGroup and the fabulous Jürgen M Plitzko. #cryoET.
0
0
0
RT @Plusk4u: Dynamin-like proteins at the nuclear envelope? That and other surprises in excellent work by @PhilipMannino1 with help from @N….
0
24
0
RT @RockefellerUniv: Postdocs! Apply now for the Exceptional Scholars Workshop, a program for mentorship of postdoctoral fellows from under….
0
18
0
RT @JCellBiol: .@udi_yael et al. @RoutLab_RU present a new method for quantitative subcellular fractionation of a wide range of mammalian c….
0
25
0
RT @retrogenomics: First paper: by @DrMartyTaylor @macro_momo @rome_tx @bengrbm @RoutLab_RU @KathleenHBurns and man….
0
7
0
RT @retrogenomics: Did you ever wondered how "jumping genes" actually jump? 2 papers now published in @Nature show the 3D structure of the….
0
56
0
RT @ArmrYshr: Excited to share my final PostDoc work! Introducing MagIC-cryo-EM🪄 & DuSTER🧹, these methods reduce cryo-EM sample requirement….
0
61
0
RT @leslievosshall: Biomedical PhD with no more than 24 months of postdoc experience? Interested in learning more about the @HHMINEWS Hanna….
0
91
0
👀👀👀.
(1/2) #nuclearpores facilitate rapid changes in nuclear size in response to osmotic stress. This is relevant under changing environmental conditions. Work @pc_hoffmann Henry Kim @aobarska and others in collaboration with @HummerLab now online:.
0
0
1
Check out this great work led by @BarakRaveh, a first of its kind, integrative spatiotemporal map of the NPC explains the main molecular mechanisms underlying nuclear transport! A NCDIR @IntActOme special with our friends @salilab_ucsf, @DavidCowburn1 and @TheVillaLab.
New year, new manuscript! Our work on mapping transport between the nucleus and the cytoplasm is now on BioRxiv, and it's time to embark on a journey through the nuclear pore complex. Nuclear what? Bear with me!.
0
1
4
RT @BarakRaveh: New year, new manuscript! Our work on mapping transport between the nucleus and the cytoplasm is now on BioRxiv, and it's t….
0
11
0
Here is a link to Rout lab member @_themovingvan_ tweetorial (Xtorial?) on our major findings. Congratulations also @ArthurZalevsky and @dfhoyosg .
So excited to share our story revealing structures, functions and adaptations of the human LINE-1 retrotransposon, an ancient genetic parasite that has written 1/3 of the human genome and is implicated in cancer, aging, & autoimmunity. Now out in @Nature
0
1
4