Neelesh Soni
@neeleshsoni03
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Researcher in Computational Sciences @salilab_ucsf, @UCSF | Ph.D and BS-MS @IISERPune | Interested in designing algorithms for real-world problems
San Francisco
Joined January 2010
From preprint to journal. Our nuclear gatekeepers have successfully unlocked the gates to Cell (Journal) https://t.co/ZA1xVgZtCD
#NPC #integrativemodeling Congrats to team @dgvjayS @JoshHutchings94 @ig_ech @RoutLab_RU @salilab_ucsf @TheVillaLab Animation https://t.co/Av7fD7Yfs0
Tiny gatekeepers of our nucleus decide what gets in and out. Follow our study on Yeast and Mammalian NPC baskets and unravel the molecular structure of these cellular bouncers! Don't miss the side-by-side comparison in the video. #IntegrativeModeling
https://t.co/Fi047oKYGz
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Insightful and thought-provoking commentary on the nuclear basket model in @CellCellPress by @LuskingL Check it out:
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Navigating the seas of science and the waters of Tomales Bay! Having a blast at the lab retreat.
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1/10 📢 IISER Pune is organizing a Molecular Biology Workshop for Underrepresented Groups in Education. All-expenses paid, 7-day workshop for Masters students from marginalized groups in Category Y and Z cities of India.
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🎉Celebrating our latest publication on the NPC basket structure in Cell https://t.co/9H5sDaxpmJ!
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APPLY for PhD program at IGIB: There are lot of openings at IGIB for *computational biology* domain for this coming Dec-Jan session, including my lab. Please apply if you are interested. Feel free to write before for any informal queries.
Applications are invited for PhD program @IGIBSocial for the January 2025 session, through @AcSIR_India. For more details, visit https://t.co/XcZVOq1nKu
@souvik_csir @CSIR_IND @HRDG_CSIR
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Don't miss a short tweetorial on our NPC basket study, published in @CellCellPress! https://t.co/BYrVJXYC4F
#NPC #NuclearBasket #integrativemodeling
Our work on the architecture and model of the #NuclearBasket is now out @CellCellPress. https://t.co/OmHf7ECJns. @HHMINews, @IntActOme #NPC #teamtomo A short tweetorial follows
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Fantastic work. Great idea @Weinberger_Lab. Stealing proteins from the virus! Exciting results from engineered TIPs and modeling predictions @NehaKhetan4. Kudos to the team! 🎉 #HIVResearch #AntiviralTherapy #ProteinEngineering
Excited to be part of this novel antiviral therapy study! Engineered HIV-TIPs reduce viral load in monkeys, predicted to reduce transmission in humans: single-dose and escape-resistant! Congratulations to the team! @Weinberger_Lab @GladstoneInst @
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Exciting research from @IISERPune sheds light on the dynamic interplay between dynein and microtubules! Computational modeling done by @NehaKhetan4 beautifully captures how dynein generates wave-like oscillations. Congratulations to the authors! #Science #ComputationalModeling
🔴 A molecular motor capable of transporting cargo within a cell, generates wave-like oscillations in microtubules in a purified synthetic system, researchers at @IISERPune have found. Find more: 👇🏻 https://t.co/ruREokS4Ls
#NatureIndia
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It cannot be done, they said.. It's too flexible, they said.. 😁 https://t.co/6wDKmXeXfL
#NPC #teamtomo #integrativemodeling by @dgvjayS @neeleshsoni03 @JoshHutchings94 @ig_ech et al. Great collaboration w/ Qiang Guo, Brian Chait, Javi Fernandez-Mtnz, @RoutLab_RU @salilab_ucsf
biorxiv.org
The nuclear pore complex (NPC) is the sole mediator of nucle-ocytoplasmic transport. Despite great advances in understanding its conserved core architecture, the peripheral regions can exhibit...
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Tiny gatekeepers of our nucleus decide what gets in and out. Follow our study on Yeast and Mammalian NPC baskets and unravel the molecular structure of these cellular bouncers! Don't miss the side-by-side comparison in the video. #IntegrativeModeling
https://t.co/Fi047oKYGz
Proud to share the result of an amazing collaboration with Javi Fernandez-Martinez, @RoutLab_RU , and @TheVillaLab ! https://t.co/UslJWdFKIW Congrats to @dgvjayS @neeleshsoni03 @JoshHutchings94 @ig_ech and the team! And check out the video by @neeleshsoni03 ! #NPC
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The @UCSFSenate's 66th Annual Faculty Research Lecture in Basic Science is being awarded to Andrej Sali @salilab_ucsf for his work on computational biology and integrative structure modeling! Attend his lecture on 04/16 at Mission Bay Campus. Learn more: https://t.co/ZG0gDQYy1G
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We @QBI_UCSF @salilab_ucsf are recruiting 6 #postdoc in #computational #structuralbiology to work with multi-disciplinary teams @CancerCellMap of systems & structural biologists, as well as infectious disease experts! For more info check
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We are excited to share our recent work on hypoxia-driven epigenetic reprogramming that regulates the expression of a splicing factor to contribute to breast cancer progression. Thank you, @India_Alliance, for supporting our work. https://t.co/O0pRqzkCuE
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In this hypothesis piece, we propose that nuclear hormone receptors act as integrators of sensory information in free-living nematodes: https://t.co/wEKWKHw3Lz (1/n)
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#365IndianWomenInSTEM Neha Khetan is a computational biologist at @IISERPune who focuses on quantitative analysis, mathematical modelling & simulations of biological processes. A recent paper on the hexagonal patterns formed by microtubules and motors. https://t.co/0m1KCrOZT4
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(1/5) Some tips for the next generation of reviewers. (Because mine is doomed!) Your work as a reviewer consists of answering only three questions: #AcademicChatter #AcademicWriting
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People who live beyond 105 years tend to have unique genetic signatures that make their bodies more efficient at repairing DNA https://t.co/wFiNROaGju
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Happy to share our paper on hexagonal patterns formed by microtubules and motors. Thanks to @AthaleLab, Janet Chenevert, @IISERPune and @J_Cell_Sci. Self-organized optimal packing of kinesin-5-driven microtubule asters scales with cell size.
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