Our Immune Cell Biology collection emphasizes cellular dynamics, immune regulation, and disease mechanisms. Explore the mechanisms of dendritic cell regulation, T cell migration, neutrophil spreading and macrophage motility in tumor invasion: #AAI2025

Lipid synthesis supports membrane growth and organelle biogenesis. Sunyoung Hwang, Eduardo Torres et al. @UMassChan show that synthesis of sphingolipids, mainly long-chain bases, is essential to increasing nuclear membranes during #CellDivision.

Spindle morphology changes rapidly & dramatically at the meiosis to mitosis transition in early embryogenesis. Cantwell et al @berkeleyMCB reveal differential CK2 regulation of the RanGTP pathway of spindle assembly in meiosis & mitosis driving this change

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Stathatos, Dunleavy, O'Bryan et al. @UniMelb reveal essential roles for TUBD1 in male germ cell development and male fertility, specifically in stabilizing the meiotic kinetochores during division and shaping the sperm head via the manchette. #Development

The E3 ligase Parkin ubiquitinates many proteins. Joanna Koszela, Helen Walden and colleagues @UofGlasgow identify and biochemically validate a direct Parkin interaction with a substrate, Miro1.

Stewart, @m_p_miller et al. @UofUBiochem show that Stu2 displays dynamic localization patterns in the #CellCycle, with different kinetochore and microtubule distributions during distinct phases.

Juhi Narula and Sarah Wignall (@swignall) @NorthwesternU identify a new role for the conserved kinase PLK-1 in suppressing centrosome maturation in oocytes, which surprisingly is opposite to its role in mitosis. #CellCycle #Genetics #Development

Davide Basello, David Staněk et al. @imgprague show that coilin oligomerization and its interactions with RNA and snRNPs are essential for Cajal body integrity and propose a mathematical model describing Cajal body dynamics.

Bobby White, Pawel Swietach et al. @OxfordDPAG show that sustained hypoxic stabilization of HIF1a requires alkaline conditions, which may not be representative of most under-perfused tumors. #CellSignaling #Cancer #CellMetabolism #Hypoxia

Spotlight: Sabina Elmi and Jesper Nylandsted highlight work by Williams and colleagues ( that provides new insight into the role of annexins in the repair of plasma membrane lesions. . #Biochemistry #membrane #lipid

We're hiring! The Journal of Cell Biology (JCB) seeks Scientific Editor or Senior Scientific Editor, dependent on experience. Join our team in New York City! Apply here 👉 . #STEMjobs #LifeScienceJobs #PublishingJobs #ScienceJobs

RT @Jor_Ferreir: Beautiful work and images are amazing.

New study showing the development of pan-Expansion Microscopy by Morgan, King et al. @YaleMed to reveal the molecular composition and structural plasticity of individual nuclear pore complexes including LINC complex-dependent dilation.

Mackin, Samuel et al. @bcmhouston reveal that the kinase LKB1 is crucial for migration & nuclear positioning of a specialized type of retinal ganglion cell called F-RGCs. Its absence leads to misplacement, altered morphology & increased cell death

Atg9 is a conserved regulator of #lysosome repair. Ruoxi Wang & Eric H. Baehrecke discuss new studies by Peng et al in JCB ( and De Tito et al. in @Dev_Cell (:.

Tatsuya Hirano @riken_en reviews mitotic genome folding with an emphasis on the mechanistic aspects of #condensins, #topoisomerase II, and #histones. . #CellCycle #CellDivision #Genetics #Mitosis #Chromatin

RT @timisstuck: One of the final papers I handled over at JCB 🥲.Very happy for these authors linking metabolism with outgrowth of micro met….

RT @CassieJClarke: Delighted to share the work of @GounisMichalis describing how metabolic reprogramming of micrometastatic cells influence….

Wood, Wolff et al. of Paula Cohen's lab @Cornell show that cyclin N-terminal domain containing 1 (CNTD1) is a critical regulator of crossover formation during prophase I of #meiosis in females. #Genetics #CellCycle #CellDivision

Attending @KeystoneSymp's meeting on #Neuroimmunology and #Neurodegeneration? Meet our Executive Editor Tim Spencer who is attending! Bring all your publication-related questions 🔬 💻 📄 . ✉️ Email Tim: . #ksneuroimmune25 #ksneurodegen25