
ROME Therapeutics
@rome_tx
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We are developing novel therapies for cancer and autoimmune diseases by unlocking the role of the dark genome in human health and disease
Boston, MA
Joined February 2022
Wishing you a season of love & light! We’re proud of our 2024 accomplishments illuminating the #DarkGenome and advancing LINE-1 RT inhibition as a promising therapeutic approach for autoimmune & neurodegenerative diseases. Looking forward to further pioneering efforts in 2025!
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Thank you to all speakers, panelists, poster presenters, in-person & virtual attendees, our co-hosts (@Enara_Bio, @NucleomeTx & @nyulangone), and sponsors! We’re so proud of how far the #DarkGenome field has advanced, pioneering a new frontier in biology and medicine. #DGS2024
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We’re closing out the 3rd annual #DarkGenomeSymposium with a keynote address: “Drugging the #DarkGenome: Lessons from HIV Reverse Trancriptase.” We’re honored to have Eddy Arnold, PhD, Distinguished Professor at @RutgersU, with us to share his insights! #DGS2024
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We appreciated all of today’s short talks from selected #DGS2024 posters! We saw promising data in #ParkinsonsDisease, #RheumatoidArthritis, and #Cancer. Thanks to all presenters!
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The final #DarkGenomeSymposium panel discussion will discuss: “Are Dark Antigens the Key to Off-The-Shelf Approaches for Next-Generation Immuno-Oncology Targets?” #DGS2024
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Thank you to the Session 4 #DGS2024 presenters for sharing your insights on the promise of #DarkGenome approaches in immuno-oncology! #TranslationalMedicine #CancerResearch #DarkGenomeSymposium
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The fourth and final session of this year’s #DarkGenomeSymposium is kicking off now! Erwei Song, Daniel DeCarvalho, Abhijeet Pataskar, and session chair Sophie Papa will discuss immune-oncology and the #DarkGenome. #DGS2024
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ROME’s poster highlighting our first data in #NeurodegenerativeDisease was selected for a #DGS2024 short talk, presented by Sarah Knutson, PhD. Learn more about the therapeutic potential of LINE-1 RT inhibitors in #ParkinsonsDisease:
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The next #DGS2024 panel will discuss the question: “Is the #DarkGenome an instigator or innocent bystander in autoimmunity and neurodegeneration?” Looking forward to further illumination of this next frontier in biology and its potential role in challenging diseases.
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Fantastic presentations from the #DGS2024 Session 3 speakers elucidating the potential of #DarkGenome therapeutic approaches in a range of #AutoimmuneDiseases and #NeurodegenerativeDiseases. Thank you for sharing your research! #TranslationalMedicine #Lupus #Alzheimers
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"When we put this meeting together, we wanted to combine the basic science and translation -- developing therapies to ultimately benefit patients.". -Heike Keilhack, Chief Scientific Officer, ROME. #DGS2024 #TranslationalMedicine #DarkGenome
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This morning’s #DGS2024 session is on the role of retroelements in #autoimmunity & #neurodegeneration, chaired by our CSO Heike Keilhack. Mounting scientific evidence suggests repetitive elements like LINE-1 are implicated in a range of autoimmune & neurodegenerative diseases.
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Day 2 of the 3rd annual #DarkGenomeSymposium is starting soon. Thank you @nyulangone for hosting us and providing the beautiful space for this event. #DGS2024
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We’re proud to debut the first preclinical data of ROME’s LINE-1 RT inhibitors in #NeurodegenerativeDiseases at #DGS2024. These data in #ParkinsonsDisease will be presented at a short talk podium presentation later this morning. Learn more: #DarkGenome
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As we wrap up Day 1 of the #DarkGenomeSymposium, we want to say a hearty thank you to the Scientific Planning Committee, who put together a marvelous lineup of presenters, panelists, and posters representing a broad range of #DarkGenome topics. Thank you! #DGS2024
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We’re so pleased to have more than 30 posters being presented at this year’s #DarkGenomeSymposium. The scientific advances and momentum in this space are awe-inspiring!. #DGS2024 #DarkGenome
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Up next at #DGS2024 is a panel discussion entitled “Beyond Coding: Unraveling the Regulation and Unconventional Functions of the #DarkGenome” featuring panelists from both industry and academia.
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And that's a wrap on the #DarkGenomeSymposium Session 2 presentations! Thanks to all the speakers for the great talks focused on non-coding RNA and epigenetics. #DGS2024 #DarkGenome
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