Lucien Weiss
@LucienWeissLab
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Now at https://t.co/WnBCLXwgBQ Cell biophysics, superres microscopy, & curious-methods enthusiast. We have open positions for Interns, MSc, PhD & Postdocs!
Montréal, Québec
Joined September 2010
New preprint: we show wavefront shaping with a new kind of MEMS megapixel spatial light modulator that has fast pistoning micro-mirrors: https://t.co/uChEkDHyoT (includes code to run it fast). Great effort from project lead José @carl00s01, also with @gsdgordon @joelacarpenter.
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Woohoo! "A guide to single particle tracking" is now online! Together with @Francois__Simon & @S_vanTeeffelen, we share our thoughts on going beyond MSD analysis in Nature Reviews Methods Primers. https://t.co/Q2TlYurE4u Free read link: https://t.co/TG3IhJqTOY
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Join our faculty in Eng. Physics at Polytechnique Montréal, Quebec! Clusters in optics, semiconductors, nanomaterials, quantum, and biophysics. Quebec & Canada's funding structures support new faculty, and a research chair may be possible! Reach out! :) https://t.co/IVHAlOQn3w
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🌟 Day 2 begins with @AlonSaguy from @TechnionLive, discussing AI for enhancing spatiotemporal #SuperResolution in microscopy with #DBlink
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🚨 Meta introduces Segment Anything Model 2 (SAM 2) — the first unified model for real-time, promptable object segmentation in images & videos. 🚀SAM 2 is available today under Apache 2.0 so that anyone can use it to build their own experiences ➡️ https://t.co/mkH0Zti9d1
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Woohoo! Localization in 4D (x, y, z, λ) at video framerates - "Vortex light field microscopy: 3D spectral single-molecule imaging with a twist" Thanks, @BoyaZhang4, @koholleran! @samofmidworld, C. Zhu, M.O. Lens,@LisaMariaN91,@Ruby_Peters_,@SteveTheChemist
https://t.co/aWlIBLwkCd
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Please repost: Positions for: Project coordinator, Platform manager, Lab manager, Postdoc, Ph.D. for 4-year $21 million project to develop an integrated, active learning-based antibiotic discovery pipeline. See jobs at https://t.co/UvsnyL7Uo6. Email Brun.AB.Discovery@gmail.com
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New research led by Carolyn Ott, a senior scientist @JLS_Lab, provides the most detailed & comprehensive description yet of cilia in the mouse visual cortex, giving scientists new insights into the formation & function of this small & elusive organelle. 🔗 https://t.co/HAIyr7d7V5
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Internet friends, I’m thrilled to share our work out today in @Nature! We've developed a label-free, single-molecule method using high-finesse microcavities, enabling us to profile molecules in solution. 1/10
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What does diffusion look like in the crowded bacterial cytoplasm? Is it as weird as people say? Check out our new preprint on 3D tracking of GEMs in live E. coli from @dsvalverdem and @AlpSunol! A fantastic experiment-theory collaboration with @TheZiaLab.
biorxiv.org
The crowded bacterial cytoplasm is comprised of biomolecules that span several orders of magnitude in size and electrical charge. This complexity has been proposed as the source of the rich spatial...
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30-COLOR DNA-PAINT at 3D sub-15 nm RESOLUTION. We are overly excited to announce the publication of our latest work “Spatial proteomics in neurons at single-protein resolution” in @CellCellPress. Huge collaborative effort led by @EduardUnterauer. 1/9 https://t.co/w9BHydkC6B
cell.com
Development of SUM-PAINT, an approach that is capable of potentially unlimited super-resolution multiplexing, enables rapid visualization of distinct synapse types at single-molecule resolution.
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Another paper from our lab @SiereckiGambin - Single molecule fingerprinting reveals different growth mechanisms in seed amplification assays for different polymorphs of alpha Synuclein fibrils.
biorxiv.org
Alpha-synuclein (αSyn) aggregates, detected in the biofluids of patients with Parkinson’s disease, have the ability to catalyze their own aggregation, leading to an increase in the number and size of...
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Our work has made the inside cover! Check out "#singlemolecule #electrochemical imaging resolves the midpoint potentials of individual fluorophores..." in the latest issue of @ChemicalScience! https://t.co/XfH5Ty89fs
@WashUengineers @WashUESE
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A #SPADarray in any laser-scanning #microscope. #fluorescence #lifetime #imagescanningmicroscopy has never been so simple. Stay tuned, this is just the beginning. Soon also a thread. #BrightEye_ERC #photonresolvedmicroscopy #STED
@IITalk @ERC_Research @genoainstrument
✅ Fluorescence lifetime imaging ✅ Multicolour ✅ Super-resolution ... and everything all at once✨ (Almost) everything is possible with the SPAD Array Detector! New paper from @ZuninoAle and me, with my friends at @VicidominiLab and @genoainstrument! https://t.co/iyAgruyEqC
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Come join us at Polytechnique Montréal - Biomedical Engineering (department of MechE). Venez nous rejoindre à Montréal - Ingénierie biomédicale (département de génie mécanique)! Pour plus d'informations, veuillez cliquer ici: https://t.co/2eZmwJfcVy
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4Pi MINFLUX sets benchmarks in 3D tracking of fluorescence emitters. Check out: https://t.co/3WFn7M5jXj
biorxiv.org
We introduce MINFLUX localization with interferometric illumination through opposing objective lenses for maximizing the attainable precision in 3D-localization of single inelastic scatterers, such...
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* Soft fatigue-resistant hydrogel optical fibers that reliably function in living animals for months. * Fatigue-resistant reliable connections with other devices. * Easy and reproducible protocol. * The paper can be downloaded here. https://t.co/8uCOI5S0QJ
The @SiyuanRao lab developed flexible and fatigue-resistant optical fibers made from hydrogel that allow optogenetic manipulations in the periphery in freely behaving mice. @xinyue1liu @AnikeevaLab @ProfZhaoMIT
https://t.co/yduDHAHhcb
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Woohoo! Congratulations Janka Zsok and Elisa Dultz! A big thank you for sharing these awesome single-particle tracks!
Congratulations to Janka Zsok and Elisa Dultz for their paper on the #nuclearpore basket in collaboration with @LucienWeissLab. The first preprint from the Dultz group! "doRITE" and have a look at tracks of single NPCs. https://t.co/U14i91BZRX
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We’ve always wondered if there was something beyond CRISPR for genome editing. We now report that animals, plants, fungi and viruses have troves of programmable nucleases capable of efficient gene editing in human cells An update on our Fanzor work! https://t.co/9oAJFDmOpH 1/7
science.org
Fanzor is an RNA-guided DNA endonuclease widespread in eukaryotes and their viruses.
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Our latest @UoY_PET, @PhysLifeYork & @YBRI_UoY paper is now out in @acsnano! Interested in multiplexed optical trapping of hundreds of vesicles/beads in parallel (using low powers!)? Check it out! #science #AcademicTwitter #photonics 👇👇 https://t.co/7akT7SIElz
pubs.acs.org
Optical tweezers have had a major impact on bioscience research by enabling the study of biological particles with high accuracy. The focus so far has been on trapping individual particles, ranging...
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