Lew Lab @ WashU
@Lew_Lab
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Playing with #singlemolecules, bending light, and algorithms to see really small things. Led by Matthew Lew, Associate Professor @WashUESE @WashUengineers
St Louis, MO
Joined October 2015
"A new polarized dual-view inverted selective-plane illumination microscope (pol-diSPIM), coupled with engineering insights provided by its imaging model, offers an exciting way forward." My commentary is online in PNAS
pnas.org
Painting rich six-dimensional pictures using polarized fluorescence microscopy
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Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates:
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RT @NaturePhysics: Experiments confirm the prediction that fluid-like biomolecular condensates are defined by spatially inhomogeneous organ….
nature.com
Nature Physics - Experiments confirm the prediction that fluid-like biomolecular condensates are defined by spatially inhomogeneous organization of the underlying molecules.
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nature.com
Nature Physics - Experiments confirm the prediction that fluid-like biomolecular condensates are defined by spatially inhomogeneous organization of the underlying molecules.
A team of #WashUEngineers researchers has developed a new method to study biomolecular condensates — tiny, shifting blobs in our cells that help organize important molecules. Learn more. {link}.
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RT @WashUengineers: Matthew Lew of @WashUESE & grad student Yiyang Chen developed a new method to improve precision in molecular imaging. T….
engineering.washu.edu
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RT @naturemethods: Out today from the Lee lab @SteveTheChemist In the POLCAM paper, they make polarization cameras compatible with single-m….
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News coverage of our JPC article "Wobbly molecules get a closer look" via @WashUengineers @shawncballard.
engineering.washu.edu
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We made the cover! Check out Weiyan's work exploring the "Fundamental Limits in Measuring the Anisotropic #RotationalDiffusion of #SingleMolecules" in @JPhysChem @WashUESE @WashUengineers
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Brian's study on using the #binding #orientations of Nile blue to decipher the architectures of growing, decaying, and remodeling #amyloid #fibrils is now online in @NanoLetters !.#singlemolecule @WashUESE @WashUengineers
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Congratulations Dr. O! @wuimgsci_stuco @WashUengineers.
Congratulations to Joseph O’Sullivan, the Samuel C. Sachs Professor of Electrical Engineering! He was among 12 faculty and staff awarded at the 25th Annual Outstanding Faculty and Staff Awards. Read more here:
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Our work with @JaiRudra4 is online here
pubs.acs.org
Synthetic peptides that self-assemble into cross-β fibrils are versatile building blocks for engineered biomaterials due to their modularity and biocompatibility, but their structural and morpholog...
Matthew Lew & Jai Rudra's teamwork brings forth a new imaging method. Their technique highlights interlocking peptides, crucial in identifying toxic strains in Alzheimer’s. #WashUEngineers #Imaging @WashUBME @WashUESE.
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Resharing our recent cover article on imaging the architecture of peptide assemblies using #singlemolecule #orientation imaging!.
From the cover of our new issue: Researchers led by @Lew_Lab & @WashUengineers show the nanostructure of β-Sheet #peptide self-assemblies using Nile red (NR) & single-molecule orientation–localization microscopy (SMOLM). Read more 👉
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Excited to share Weiyan's work with @JaiRudra4 on using #singlemolecule orientation-localization microscopy to visualize these helical assemblies! @WashUESE @WashUengineers
pubs.acs.org
Synthetic peptides that self-assemble into cross-β fibrils are versatile building blocks for engineered biomaterials due to their modularity and biocompatibility, but their structural and morpholog...
Thanks to a wonderful collaboration with Matt Lew @Lew_Lab helping us visualize polymorphisms in amyloid-inspired peptide assemblies using Single Molecule Orientation-Localization Microscopy.
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Happy to see @Tingting_Wu_'s review chapter on 6D dipole-spread function engineering now online @WashUengineers @WashUESE .A big thanks to @JinyangLiang for putting such a great volume together!
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Our work has made the inside cover! Check out "#singlemolecule #electrochemical imaging resolves the midpoint potentials of individual fluorophores. " in the latest issue of @ChemicalScience! @WashUengineers @WashUESE
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Congratulations to Prof. Jin Lu, now at the National Center for Nanoscience, whose work on single-molecule electrochemical imaging is now online in @ChemicalScience! #MyFirstChemSci
Single-Molecule Electrochemical Imaging Resolves the Midpoint Potentials of Individual Fluorophores on Nanoporous Antimony-Doped Tin Oxide
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Great to hear W.E. on the podcast with wisdom for young scientists and engineers! #SingleMolecule @WashUengineers.
Prof W.E. Moerner is the Harry S. Mosher Professor of Chemistry and is a Professor, by courtesy, of Applied Physics at Stanford University and an alum of #WashUESE. He recently appeared on The Master Mind Podcast. Listen here:
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Join us for @Tingting_Wu_'s PhD defense, "Information-Rich #6D #SingleMolecule Imaging Using Optimization," tomorrow at 1 PM CST in Rodin Auditorium! @WashUESE @wuimgsci_stuco @wustlspectra @WashUengineers
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