Steve Quinn
@Steve_Quinn_Lab
Followers
649
Following
1K
Media
98
Statuses
570
Single-Molecule Biophysicist @UniofYork 🔬| Senior Lecturer| Biophotonics, Alzheimer's Disease, Model Membranes, smFRET | 🦋 https://t.co/u71pvXcvRc.
York, England
Joined May 2019
🔬Want to develop a blood test for dementia? A fully funded PhD position is available in our lab to probe and detect single molecules! Join our team @UniOfYork! Find out more & apply by 4th Dec: https://t.co/O3mk1RkxlS
@YBRI_UoY @EI_science @Craggs_Lab
1
22
57
Delighted to share that our latest @UoY_PET, @PhysLifeYork & @YBRI_UoY work showcasing a new labeling strategy for #smFRET of complex RNAs is online in ChemPhysChem: https://t.co/OyNTNlDhBD Thanks to Dr Sarah Graham, @JemmaBetts, @chillzaa, @BPSIYork & @Craggs_Lab! 🔬🧬🧪
chemistry-europe.onlinelibrary.wiley.com
DNA scaffold-based labeling strategy is introduced that enables single-molecule Förster resonance energy transfer (smFRET) studies of the SARS-CoV-2 frameshifting pseudoknot. The smFRET measurements...
0
0
5
0
0
1
We are delighted that our latest @UoY_PET @PhysLifeYork & @YBRI_UoY paper- a handheld photonic biosensor for Alzheimer's disease blood biomarkers - is now online in Optica! 👇 https://t.co/WMA8DcDPRP Thanks to @alzheimerssoc @AlzResearchUK @EPSRC & @wellcometrust for support!
0
3
7
Congratulations to Dr Fran D'Rozario (@fransay_ ) from @PhysLifeYork & @UoY_PET for successfully defending her thesis! Thanks also to Prof Paula Mendes & @BPSIYork for examining, and to Prof Steve Johnson for supervising. Well done Fran!
0
0
2
New preprint! 🚨 I'm delighted to share our latest @PhysLifeYork @UoY_PET & @YBRI_UoY work: "Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching." Congratulations to Claudia from the team on her first manuscript! https://t.co/1GHmzqNZP5
biorxiv.org
Detergent-induced membrane solubilization is important for several biotechnological applications including membrane protein isolation, cell lysis and virus inactivation. The thermodynamic details of...
0
1
1
Single-Molecule Friends! Just 10 more days to apply for an exciting joint postdoc with @KlenermanLab, feel free to research out
0
11
20
Thanks to @UoY_PET @PhysLifeYork & @YBRI_UoY for support, and the amazing funders @alzheimerssoc, @AlzResearchUK, @ARUKYorkshire & @EPSRC without whom this project would not be possible! Thanks to researchers Katie, Guilherme, Augusto and Sian for running the experiments!
0
1
2
We are delighted to announce that our latest work - a handheld photonic biosensor for Alzheimer's disease blood biomarkers - has been accepted for publication in Optica! Check out the pre-print... 👇👇 https://t.co/tHo88Et0p8 ...and BBC story below: https://t.co/0D7PzxN8hZ
bbc.co.uk
Researchers say they are developing a device which could diagnose patients within seconds.
1
1
7
Thanks also to the utterly superb facilities @BiologyatYork led by @YorkBioimaging & to the funders @EPSRC @BBSRC @DiMeN_DTP & @wellcometrust!
0
0
4
Congratulations to Dr Sarah Graham for leading, with huge thanks to @chillzaa & @JemmaBetts, & #singlemolecule specialists @Craggs_Lab & @BPSIYork. Thanks also to @UoY_PET, @BiologyatYork, @YSBL_York & @YBRI_UoY & to the team @EI_science.
1
0
4
🚨 New preprint!🚨We introduce a DNA-scaffold strategy for efficient dye labelling of structured RNAs, enabling #smFRET studies of freely-diffusing SARS-CoV-2 pseudoknots🧬 👉 https://t.co/1XFSplRefV
#smFRET #RNA #biophysics #SARSCoV2 #singlemolecule #Covid
biorxiv.org
Single-molecule Förster resonance energy transfer (smFRET) studies of highly structured RNA molecules are often frustrated by issues with efficient dye conjugation. Here, we develop a DNA scaffold-...
1
2
13
Thanks to @UoY_PET , @EPSRC, @YBRI_UoY and @EI_science for support! Thanks also to the Molecular Interactions team & @YorkBioimaging @BiologyatYork for making #smFRET capabilities possible!
0
1
1
🧬New Pre-Print!🧬 @fransay_ explores how pH-sensitive DNA triplexes retain reversible switching in solution, and when densely immobilized on surfaces - a step towards hybrid electronic DNA devices? 👇👇 https://t.co/cnew6FKyem
#DNAnanotech #bioelectronics #smFRET #DNAmachines
biorxiv.org
Dynamic DNA machines exploit the specificity of base pairing and/or sensitivity to the local environment to control the reversible switching of DNA constructs between conformational states. One such...
1
2
5
New job opportunity! @LindemannTrust is recruiting 2 freelance roles: a Trusts and Grants Fundraiser and Philanthropy Events Fundraiser. For more info, and to apply, visit: https://t.co/ufUbQGTjd1 Closing date: Tuesday 19th August.
lindemanntrust.co.uk
Support If you are interested in supporting our activities, either through sponsorship or by volunteering your time, we would love to hear from you. Below are just a few examples of ways you might be...
0
1
2
🙌 Check out this brilliant example of our benchtop single-molecule fluorescence spectrometer in action! @chillzaa and his team have identified a new protein-sensitive riboswitch in viruses, which presents an attractive new target for antiviral drugs. Great work 👏 #smfret
New preprint alert! 🚨👇 I'm delighted to share the latest research from @JemmaBetts in our group: ‘A new protein-dependent riboswitch stimulates ribosomal frameshifting’. Huge congratulations to Jemma for the first manuscript of her PhD! ✨ https://t.co/EVaYSclK4k
0
1
3
🚨New Preprint!🚨Latest research led by @JemmaBetts & @chillzaa reveals the structure of a protein-dependent riboswitch, revealing new mechanistic principles that could inspire novel antivirals! Thanks to @EPSRC, @gen_res_uk, @EI_science , @YBRI_UoY & @UoY_PET for support! 👇👇
New preprint alert! 🚨👇 I'm delighted to share the latest research from @JemmaBetts in our group: ‘A new protein-dependent riboswitch stimulates ribosomal frameshifting’. Huge congratulations to Jemma for the first manuscript of her PhD! ✨ https://t.co/EVaYSclK4k
0
0
3
Fantastic evening with @LindemannTrust colleagues @royalsociety Summer Science Exhibition 2025! Brilliant talk by former Fellow @Chandri62281832 on the ethics of AI! Well worth a visit! #SummerScience
0
0
3
In this Editorial, Steven Quinn (@UoY_PET) examines the urgent and global need for democratized blood-based #biomarker diagnostics in #Alzheimer's disease 🔬 📜Read the #openaccess article here: https://t.co/LrB0KN41Rv
0
3
5
Congratulations to Dr Sarah Graham @PhysLifeYork & @UoY_PET for successfully defending her thesis! Thanks also to Dr Tara Sabir & @ANoyLab for doing the honours as examiners, @BPSIYork for co-supervising & @chillzaa for all the help along the way! Well done Sarah!
0
1
8