Stefan W. Hell
@Stefan_W_Hell
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Physicist, Nobel Laureate in Chemistry, Father of four
Joined September 2020
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Huge congratulations Katalin! So deserved for the live-saving work that hardly anyone expected a decade ago. Creativity + perseverance is a recipe for real breakthroughs and
#NobelPrize
@kkariko
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Folks, let’s open up a new chapter in the quantification of protein movements and conformational changes!
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Powerful microscope captures motor proteins in unprecedented detail
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MINSTED goes Ångström 😎
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#STED
at Å precision! See
New article by Weber, von der Emde et al. Fantastic applications ahead; stay tuned!
#Nanoscopy
#Superresolution
#Microscopy
@mpi_nat
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Superresolution fluorescence microscopy with molecule-size resolution now walks on two feet: see our preprint on MINSTED nanoscopy by Weber, Leutenegger et al
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Happy holidays and a good resolution for 2024 🔬😀!
"It's not a goal that is the goal, it's actually the path towards the goal."
2014 chemistry laureate Stefan Hell shares his best career advice for young scientists and researchers.
#NobelPrize
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You think you know how kinesin walks on microtubules - after all, you know the famous cartoon…
#MINFLUX
now forces us to think differently.
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Enhanced incorporation of subnanometer tags into cellular proteins for fluorescence nanoscopy via optimized genetic code expansion | Proceedings of the National Academy of Sciences
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The roaring twenties of microscopy have just begun…
Building on Nobel-winning research into optical superresolution microscopy, researchers have now achieved nanometer and millisecond precision simultaneously—good enough to watch the motions of proteins in real time.
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MINSTED is on the fast track 🤓
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Interacting with so many bright young minds is a real privilege and highlight for me, every year.
Mind-blowing talk by
@Stefan_W_Hell
, bringing fluorescent microscopy to Angstrom resolutions.
#LINO23
@lindaunobel
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#STED
shows a new and unexpected facet of its capabilities: quick, effective and precise fluorophore tracking.
#MINFLUX
. Good work Henrik, Lukas, Michael, Mira...
Out today from
@StefanHellLabs
MINSTED enables single-particle tracking with nanometer/millisecond spatiotemporal precision.
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Relaxing after a series of spectacular lectures on the very latest developments in astronomy, biology, mathematics and chemistry at
@CasinaPioIV
. What a day!
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Bioorthogonal Caging-Group-Free Photoactivatable Probes for Minimal-Linkage-Error Nanoscopy | ACS Central Science
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A place that makes you think and feel humble: Albert Einstein's summer home in
#Caputh
near Berlin, where he spent three happy years of his life before his life and that of millions of others were struck by terrible events.
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Three-dimensional single-cell transcriptome imaging of thick tissues
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It’s wonderful to see so many successful alumni and current lab members driving the field forward and making an enormous impact. I am very proud of all of you!
The
@StefanHellLabs
family at
#SMLMS2023
— 🍩's past and present united!
@AndImaging
, R. Gerasimaite,
@IlariaTesta4
@LOstersehlt
@VicidominiLab
@BalzarottiFran
, I.Jansen,
@RLincolnChemist
@ElisaDEste
, J.O.Wirth, S.J.Sahl,
@wmarkbates
@bewersdorflab
Missing:
@JGDanzl
&
@SSchnorren
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Photoactivatable Xanthone (PaX) Dyes Enable Quantitative, Dual Color, and Live‐Cell MINFLUX Nanoscopy - Remmel - Small Methods - Wiley Online Library
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Glad to see Thomas Ebbesen, a truly outstanding chemist and physicist with whom I shared the 2014
@KavliPrize
in
#nanoscience
.
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Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX
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🤔Guess what comes after kinesin?
Dynein, of course!
See our latest paper by Jonas Schleske et al
#MINFLUX
in living cells.
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MINFLUX is hot on the heels of kinesin in cells
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4Pi MINFLUX sets benchmarks in 3D tracking of fluorescence emitters. Check out:
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Our youngest, Wolfgang, got his t-shirt signed by the captain of his favorite soccer team VfL Wolfsburg after they beat Union Berlin 2-1 (who will play Real Madrid on Wednesday).
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A fantastic student. I love working with her.
Katarina Chapman
#PhysikerinderWoche
- Katarina is a Ph.D. student in the
@StefanHellLabs
at the
@mpi_mr_hd
@maxplanckpress
in Heidelberg, working on
#MINFLUX
#nanoscopy
...
@BMBF_Bund
#womeninscience
#womeninphysics
#physikerin
👩💻👉
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Nice to see the cristae come out so clearly. 👌
Exploring mitochondria dynamics with
#abberior
LIVE ORANGE mito! Our
#STEDYCON
microscope captures the live-cell magic, deconvolved and rendered with
@svi_huygens
. Thanks to
@CrisBenincaPhD
from
@UCLA
for the cells.
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#MINFLUX
now changes the game of protein tracking:
🌶😎🌶

MINFLUX dissects the unimpeded walking of kinesin-1
See also spectacular work by
@JonasRies
lab in living cell:
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The pleasure was all mine! It made me happy to see you record great data and being happy with the
#MINFLUX
system.
I had a lovely visit to
@Abberior
in Heidelberg and tried my favourite protein Nup98 with Minflux! The resolution is mind-blowing!🤯🤩 I asked Clara how often they meet with Stefan Hell here. She said roughly once per month. AND then Stefan just came in! I was super excited!😇
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So nice seeing Queen Silvia of Sweden again, on the occasion of her receiving the honorary citizenship of Heidelberg.
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It has been wonderful to meet
@OnsMSaad1
, formerly of the
@bewersdorflab
at Yale and hear about her great
#panExM
work!
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I look forward to presenting at the conference!
We are delighted to welcome Professor Stefan W. Hell (who received the Nobel Prize in Chemistry in 2014) for a seminar about fluorescence
#spectroscopy
on Monday, December 11 at 11 am.
👇Join the conference via Zoom here :
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I look forward to participating at this year’s event! Great people and great science, as always.
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I really enjoyed reading this fantastic study. Congratulations to Ardem, Eric and the whole team!
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Schnell auch im Nanometerbereich – Durchbruch in der hochauflösenden Fluoreszenzmikroskopie
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Fancy a donut? Makes you feel twice as good: when you eat it and when you see how it makes hot data…
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Another cutting-edge application using
#MINFLUX
More will follow soon.
Published in Cell:
#NINJ1
mediates plasma membrane rupture by cutting and releasing membrane disks.
#MINFLUX
imaging was used to confirm ring formation of endogenous NINJ1.
Great collaborative project from
@WuLabHarvard
@LironDavid2
@BobbyHollings
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An ingenious combination of design, suitability for everyday use and low cost. I think it’s the nicest car that Peugeot ever built 😊…
Talking about France, while visiting
@Abberior
's new building in Göttingen recently, I had the pleasure to learn that
@Stefan_W_Hell
owns a french car and likes driving them since the 1990s ! Maybe an early inspiration for studying molecular motors with
#MINFLUX
?
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Congratulations Siva! Excellent work. Also, it’s very rewarding to see that DyMin STED and MINSTED were helpful. By coincidence another MINSTED paper - on tracking- came out today in Nature Methods. I’m sure it’ll be useful, as well:
On the
@NeuroCellPress
cover is our ‘Lord of the Vesicles’! Largest synaptic vesicle pool in the brain carry two
#transporters
, VGLUT1 and ZnT3. Very rewarding collaboration with JahnLab
@Stefan_W_Hell
@miloseviclab
@apoliscope
@mpi_nat
@yourUMG
!! Thanks
@sci_illustrate
!
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