Julio Saez-Rodriguez
@JulioSaezRod
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Computational Biologist, Head of research @emblebi, part-time @UniHeidelberg, codirector @DR_E_A_M challenges. Low-activity account, mostly retweets @saezlab
Heidelberg, Germany
Joined March 2011
We present NetworkCommons, a unified platform 🪐 for network biology, providing access to omics data, knowledge, and contextualization methods, all with a consistent API 👇 Paper: https://t.co/Fm6FEHQcl2 Docs: https://t.co/Sw6CskluRu
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Congrats to @teichlab @humancellatlas We are happy to have contributed a bit to https://t.co/8q8YuXoBvl, improving robustness of scAutoQC @slobentanzer, & cell-cell communication analyses @DanielBDimitrov with LIANA+ ( https://t.co/MsFr5uWCJi), supervised by @juliosaezrod
liana-py.readthedocs.io
main GitHub issues Documentation Status codecov Downloads LIANA+ is a scalable framework that adapts and extends existing methods and knowledge to study cell-cell communication in single-cell, spat...
🚨 New publication alert! 🚨 As part of the exciting #HCA publication bundle in @Nature, we reveal metaplasia’s role in inflammation in gut diseases, powered by a single-cell atlas of the entire human gastrointestinal tract. 🌟 https://t.co/NL0SlzNXYk
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What are the key disrupted multicellular processes in heart failure? In our new work we combine 23 years of molecular data with recent single-cell atlases to draw a cross-study patient map. How did we navigate the heart failure space? 🧵⬇️ https://t.co/aRDqdQxC5j
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Are you a student in France studying computer science, statistics, or bioinformatics? @FranceintheUK has opened a new round of internships hosted at EMBL-EBI. Find out more and apply. https://t.co/o9QdzfUKyn
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Welcome @TimCoorens to @emblebi ! Looking forward to working together; Tim is hiring postdocs 👇 #emblebiresearch
Very happy and excited to announce that I'll be starting my own research group at @emblebi! The group will focus on lineage tracing, somatic evolution and the origins of cancer. Interested in doing a postdoc in the group or know someone who is? Please reach out!
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📢 Introducing CORNETO: a unified, knowledge-driven framework for multi-sample network learning & modeling via constrained optimization, supporting a wide variety of network methods and prior knowledge 💻Code: https://t.co/OuM9Acrs9U 📜Paper: https://t.co/XFjEbKMAAL 🧵👇
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Our work with @schirmerlab in multiple sclerosis (MS) is out today in @NatureNeuro. We investigated lesion progression and cell-cell communication events in MS using snRNA-seq and spatial transcriptomics 🧠 See below ⬇️ https://t.co/j6LIwv4IgU
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We're hiring! Join @saezlab as a Staff Bioinformatician at Heidelberg University- Work on multi-omics data in heart disease research (CRC 1550). PhD in computational biology or relevant experience required. 📅 Apply by Nov 18, 2024.
jobrxiv.org
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
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How good is our understanding of signaling pathways? In this study together w/ @savitski_lab @EMBL, we combine multiple state-of-the-art resources to evaluate signaling pathway inference using phosphoproteomics and kinase-substrate networks https://t.co/T2iIKGYuiZ
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Kidney fibrosis as a molecular process is poorly understood. In this new study together w/ Pepperkok lab @EMBL, we present a time-resolved #multiomics + computational network modeling approach in combination w/ phenotypic assays to study #kidneyfibrosis
https://t.co/9I1axrjUYl
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We're also hiring a Research Software Developer. Join us to redesign @omnipathdb and work with Postgres, Python, TypeScript & more) in systems biomedicine. PhD or relevant experience in engineering, CS, or computational bio required. Apply by Nov 18, 2024.
jobrxiv.org
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
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Post-doc opening to join our lab @emblebi #EMBLEBIresearch to develop/apply #bioinformatics methods to study cellular organization, int/extra cell networks to extract disease mechanisms from sc and spatial multiomic data, with @YvanSaeys, supp by @CZI 👇 https://t.co/c6aecDDZ55
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🫀Check out our new study on fibrosis in HFpEF, a result of great team effort with the @LeuschnerLab #heart
scRNA-Seq profiling of 🫀interstitial cells reveals fibrosis in HFpEF to be distinct from HFrEF including the induction of basement membrane collagens and a protective ⬆️ of ANGPTL4 in murine and human HFpEF | led by @LauraWienecke and @jan_lanzer
https://t.co/DgALDoP5Zn
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👉Consider joining us for a post-doc at @emblebi & @ASTRAZENECAUK as part of the EAZPOD program to study multicellular mechanisms associated with #cancer treatment resistance! #postdoc
https://t.co/Pfyp0P1fEf
ebi.ac.uk
EMBL-EBI-AstraZeneca postdoctoral fellowships (EAZPOD)
Apply to the 2024 EAZPOD Programme at EMBL-EBI & AstraZeneca in Cambridge. Work on cutting-edge computational biology in oncology with world-class scientists & access to state-of-the-art facilities! Learn more & apply: https://t.co/ji3s10HGbn
#Postdoc #Oncology
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Postdoc Opportunity. Join the Saez Rodriguez group! Develop computational methods to explore cellular organization & disease mechanisms using multi-omic data. #Postdoc
https://t.co/lpvhPtGKEW
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🚨Closing soon: ESPOD fellowships in collaboration with @sangerinstitute - the perfect opportunity to combine experimental & computational approaches for cutting-edge life science research! 🗓️Deadline 29 September Explore funding, themes and timelines👇 https://t.co/Qe3NZV7YfY
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Check the latest @DR_E_A_M paper, evaluating methods to deconvolve cellular composition from bulk gene expression, with contributions from our (former) @alvaldeolivas & @JulioSaezRod 👇
Paper is out! Deconvolve cellular composition from bulk gene expression
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Still time until 15th September to submit an abstract to join us in Berlin in the @SpatialBio conference 👇
Important information: The abstract deadline for the ESSB conference (December 12/13 2024) has been extended. It is now possible to hand in your abstract until September 15th! Submit and become part of the ESSB community! #spatialbiology #ESSB
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Looking for a PhD? Take a look at @embl programme. Among many cool projects, we are recruiting @emblebi, including one position to study host-microbiome interactions in the gut, an @ERC_Research project w @giacomello_lab @ejvillablanca @ZellerGroup
Applications for the EMBL International PhD Programme are open! 👀 The programme offers fully funded PhD positions at EMBL’s six sites across Europe 🌍 Have a look at this opportunity to start your career in the life sciences here: https://t.co/wlj1i614ey
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📣 The much-revised manuscript of LIANA+, our all-in-one solution to study cell-cell communication from single-cell, spatial, and multi-omics technologies, is now published in @NatureCellBio
https://t.co/KkHX3GVLn1
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