Lucas Schirmer
@schirmerlab
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Neurologist physician-scientist @UniHeidelberg focusing on #SingleCell, #SystemsBiology, #NeuroGlia, #MultipleSclerosis, #progressiveMS and #Neuroimmunology
Mannheim, Germany
Joined February 2019
@saezlab @NatureNeuro This has been a wonderful journey decoding the MS lesion rim dynamics using paired transcriptomics. Big thanks to @Cels121 and @PauBadiaM for carrying this over the finish line! Great collaboration with @saezlab and happy to see this back2back with the work of @EggenBart lab.
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Returning from our annual society meeting with a bunch of new ideas, great catching up with friends and colleagues. Wonderful platform talks about MS and IBM transcriptomics by team members @TimTrobisch and @SvenWischnewski - well done!
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Thanks to all lab and division members, mentors and supporters of our research over the past years - I feel immensely proud to have met wonderful people along my path and look very much forward to tackling the scientific questions that lay in front of us! @Neuro_MA @schirmerlab.
👏The MCTN congratulates Lucas Schirmer @schirmerlab @unimedizinma @MCTNeuroscience @UniHeidelberg, who received the Science Award of the German Society of Neurology at the DGN Congress currently taking place in Berlin. 👉
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RT @MCTNeuroscience: 👏The MCTN congratulates Lucas Schirmer @schirmerlab @unimedizinma @MCTNeuroscience @UniHeidelberg, who received the Sc….
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RT @NatureNeuro: And, examining subcortica lesions identified niches such as perivascular spaces, the inflamed lesion rim, and the lesion c….
nature.com
Nature Neuroscience - Lerma-Martin et al. generated a paired single-nucleus RNA sequencing and spatial transcriptomics dataset from subcortical multiple sclerosis lesions, identifying spatial...
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RT @kellie_horan_: Two fantastic papers were published today in @NatureNeuro highlighting some major advances in understanding MS using spa….
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RT @saezlab: Our work with @schirmerlab in multiple sclerosis (MS) is out today in @NatureNeuro. We investigated lesion progression and cel….
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RT @bayraktar_lab: WebAtlas for visualising single cell & spatial data online is out: With @Muzz_Haniffa @BioinfoTo….
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RT @clintomics: Now out - WebAtlas pipeline for visualizing and processing integrated single cell and spatial transcriptomics data @nature….
nature.com
Nature Methods - WebAtlas pipeline for integrated single-cell and spatial transcriptomic data
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Thrilled to feature our latest review on iron scavenging and myeloid cell polarization with a particular focus on multiple sclerosis and functions of iron-loaded macrophages at the rims of chronic active MS lesions.
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RT @MCTNeuroscience: REVIEW @TrendsImmuno @schirmerlab.Iron scavenging and myeloid cell polarization.👉
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RT @MCTNeuroscience: Bei der akademischen Mittagspause von.@ResearchLifesci ist MCTN-Forscher Prof. Dr. Lucas Schirmer (@schirmerlab) mit s….
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RT @ResearchLifesci: Nächsten Montag beginnt die letzte Woche der Akademischen Mittagspause 2024! @majendrusch, Kai Melde, @schirmerlab, Ka….
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RT @martingarridorc: Very happy to see this paper out in @NAR_Open !! Congrats to @vicpaton on his first publication, and big thanks to all….
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RT @FdeCastroS: Proud of the @GlialRede+@redglial (@fernandes_lab+myself) symposium on #MultipleSclerosis from different #glial perspectiv….
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RT @Nature: Nature research paper: Senescent glia link mitochondrial dysfunction and lipid accumulation
nature.com
Nature - The authors identify naturally occurring senescent glia in aged Drosophila brains and decipher their origin and influence, determining that they can appear in response to neuronal...
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RT @SvenWischnewski: Happy to share our latest work on single nucleus and spatial transcriptomics in inclusion body myositis!.@NatureAging….
nature.com
Nature Aging - Inclusion body myositis (IBM) is a progressive inflammatory muscle disease of unknown cause, prevalent in older adults. Through spatial and single nuclear profiling, the authors...
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RT @MCTNeuroscience: @schirmerlab @SvenWischnewski (@mctn @unimedizinma @Neuro_MA) and collaborators provide new insights into molecular ch….
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Neue Erkenntnisse und Therapieansätze bei entzündlichen Muskelerkrankungen
nachrichten.idw-online.de
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Excited to share our work on cell type mapping of inflammatory muscle diseases highlighting a selective vulnerability of type 2 fibers in inclusion body myositis with data about potential new drug targets. @SvenWischnewski @Tlloyd4_jhmi
nature.com
Nature Aging - Inclusion body myositis (IBM) is a progressive inflammatory muscle disease of unknown cause, prevalent in older adults. Through spatial and single nuclear profiling, the authors...
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