In response to the ongoing
#COVID19
pandemic, we will deploy our large-scale genome sequencing platform, alongside regional sequencing centres, to better understand the coronavirus outbreak in the UK
We are deeply saddened to announce the death of Professor Sir John Sulston, founding director of the Wellcome Sanger Institute. He was a great scientific visionary and leader who made historic contributions to science.
#OnthisDay
we celebrate the centenary of Fred Sanger - inventor of DNA sequencing, double Nobel Laureate & self-described ‘chap who messed about in the lab’. Read more on the father of genomics
@yourgenome
#OTD
Rosalind Franklin was born in 1920.
She is best known for producing Photograph 51, an X-ray image used by Watson & Crick to create their model of the structure of DNA.
Franklin’s work was unacknowledged at the time, but Crick later called her contribution critical.
It's our anniversary! 🎉🎂
#OnThisDay
1993, the (then called) Sanger Centre opened, leading the UK contribution to the Human Genome Project 🧬
Warm wishes to all of our staff, collaborators and friends from the past 29 years
#OnThisDay
Barbara McClintock was born in 1902.
She developed theories to explain the suppression and expression of genetic info from one generation of maize plants to the next. She is the only woman to receive an unshared Nobel Prize in Physiology or Medicine.
#WomenInSTEM
🧬 The Sanger Institute was opened in 1992 to be a major contributor to the Human Genome Project.
#OTD
2000, the first draft was published, revolutionising biological research as we know it 🔬🧪🦠🧫
#HumanGenome20
It took us 25 years to read the same amount of DNA that we have been able to read in the past 12 months. Rapid technological advancements and the
@uk_biobank
project have led to a huge acceleration in our data production
#10petabases
#BigData
@illumina
Huge congratulations to Prof Matt Hurles (
@mehurles
) who has been appointed as the new Director of
@sangerinstitute
! 🎊
Currently Head of the Human Genetics Programme, Matt will formally take up the Directorship later this year.
Find out more⤵️
The mission to map the genetic code of 66,000 UK species has begun. We are delighted to welcome Mark Blaxter to lead our new Tree of Life programme & Sanger’s contribution to the UK-wide Darwin Tree of Life Project.
#SequencingLife
#OTD
1902 Barbara McClintock was born.
She won the
@nobelprize
for discovering that sections of
#DNA
can change position on a chromosome, affecting gene expression.
She is the only woman to receive an unshared Nobel Prize in Medicine.
#WomenInSTEM
We were very sad to hear of the passing of our Honorary Faculty member Sydney Brenner, a giant figure in molecular biology.
Hear more about his life and work here:
Rosalind Franklin, pioneering chemist & X-ray crystallographer, was born
#OnThisDay
in 1920. She played a key role in solving the structure of
#DNA
, but died before knowing the true impact of her work. Read more on
@yourgenome
#WomeninSTEM
"Scientific research is one of the most exciting and rewarding of occupations. It is like a voyage of discovery into unknown lands, seeking not for new territory but for new knowledge. It should appeal to those with a good sense of adventure."
Fred Sanger was born
#OTD
in 1918
As of 15:00 BST, all of our 17
@illumina
NovaSeq sequencing machines are up and running, and we’re ramping up to sequence 10,000 whole genomes a month for the
@uk_biobank
Whole Genome Sequencing Project.
#OTD
1920 Rosalind Franklin was born 👩🔬
Her research was critical to the discovery of the structure of DNA 🧬 though she received little recognition in her lifetime
Find out more about her life and work
@yourgenome
👉
#WomenInSTEM
#Franklin100
From a teenage author 📙 to aiming to map every cell in the human body🧍Sarah Teichmann has had an inspirational career so far.
Read about our Head of Cellular Genetics on our blog ⬇️
#WomenInSTEM
#HumanCellAtlas
@teichlab
We are thrilled to launch our new programme, Generative and Synthetic Genomics! 🎉
Led by
@BenLehner
, we’ll use big
#data
&
#AI
to understand & predict the effects of mutations, and engineer biological systems 🧬
With support from
@wellcometrust
Our sequencing labs are abuzz with excitement as first batch of human DNA samples arrive for
@uk_biobank
#VanguardStudy
. We will sequence whole genomes of 50,000 volunteers on
@illumina
tech to transform understanding of human
#health
.
Find out more:
What a special day. We reflect on 25 years of scientific achievements since our founding for the Human Genome Project, and look forward with excitement to the next 25 years of discovery. Thank you to all who make it happen!
#Sanger25
#Birthday
#Science
#BigData
#Genomics
The Whole Genome Sequencing project will become a game-changing resource in understanding, diagnosis, treatment and prevention of life-changing diseases.
With £9.4m from
@wellcometrust
, the Sanger Institute & partners will launch the first phase of sequencing the genomes of all 60,000 species on the British Isles.
#DarwinTreeOfLife
#BigData
Sanger Institute International Fellow
@daniela_oaks
@LIIGH_UNAM
has been awarded a
@wellcometrust
Career Development Fellowship 🙌
Her research focuses on understanding the genetic causes of acral melanoma, a type of skin cancer
Find out more ⬇️
We are delighted to launch the Sanger Excellence
#Postdoctoral
Fellowship 👩🏿🔬👨🏿🔬🧑🏿🔬
Open exclusively to early-career researchers with a degree and PhD from a UK institution, and are from a Black heritage background
Find full info ➡️
#BlackInSTEM
📢 Introducing the virtual Sanger Seminar Series! 📢 Hear from a member of our Faculty each month on their latest research.
First up, Sarah Teichmann! 🧫🧬🔬
📆 Weds 15 July, 4-5pm BST
🔗 More info 👉
#SangerSeminars
#ScienceTwitter
#HumanCellAtlas
#OTD
20 years ago the
#HumanGenomeProject
was completed, revolutionising the field of
#genetics
🧬
Today, we continue to build upon this incredible achievement, exploring new ways to use genetic information to improve human
#health
.
#OnThisDay
Dorothy Crowfoot Hodgkin was born in 1910. She won the 1964 Nobel Prize in Chemistry, and determined the structures of penicillin, vitamin B12 and insulin. She remains the only British woman to have won a science Nobel Prize.
#WomenInSTEM
19% of our staff are from the EU, and 24% of our scientific and technical staff are from the EU. We could not do the work that we do without these invaluable people.
#TogetherScienceCan
#Brexit
"One should not underestimate how important this event is in human history" – John Sulston
#OTD
1990, the Human Genome Project was officially launched 🧬
#HumanGenomeProject
#OTD
1920 Rosalind Franklin was born 👩🏻🔬
Her research was critical to the discovery of the structure of DNA 🧬 though she received little recognition in her lifetime
Find out more about her life and work
@yourgenome
➡️
#WomenInSTEM
On being asked if an institute could be named after him, Fred Sanger replied "it had better be good". We celebrated the centenary of Fred Sanger this year, and hope we have made you proud
#HoHoHighlights
#OnthisDay
we celebrate the centenary of Fred Sanger - inventor of DNA sequencing, double Nobel Laureate & self-described ‘chap who messed about in the lab’. Read more on the father of genomics
@yourgenome
Sanger International Fellow
@daniela_oaks
began her scientific career milking scorpions to study anti-venoms 🦂
Now, she is a PI
@UNAM_MX
, studying
#AcralMelanoma
, the most common
#Melanoma
in parts of Latin America, Asia, and Africa 🔬👩🏻🔬
We stand with our staff, collaborators, and friends around the world in condemning racism and discrimination. We’ve still got work to do, and we are committed to doing it.
#BlackLivesMatter
#BlackInSTEM
Applications for the Sanger Prize are now open! This prize gives LMIC undergrad students the opportunity to work in one of our labs for three months, all expenses paid 🏅🧪🔬🥼
📅 Deadline 11 December
Full info on how to apply 👉
#SciencePrize
#Funding
As we look back on this year, we would like to take a moment to once again remember Prof Sir John Sulston, who passed away in March. We owe a huge amount to John, and can only thank him for his contributions to Sanger, and science as a whole
The first human
#pangenome
has been published🧬
This important work better captures genetic variation and diversity.
Find out more in our latest blog ⬇️
We’ve now sequenced more than 5 Petabases of DNA. If you strung all the 5,000,000,000,000,000
#DNA
bases together that our sequencing machines have read, then the result would be out of this world.
#5petabases
The developing human lung has been mapped in unprecedented detail, identifying 144 cell types in the early stages of life
Acting as a guidebook to healthy lung development, this can be used to investigate how
#lungdiseases
originate
Read more 👇🏻
#OTD
1918 Fred Sanger was born 👨🔬
Known as the “father of
#genomics
”, when John Sulston asked if he could name the institute after him, Fred replied “it had better be good” ✨
Read more about Fred’s life and work 👉
Congratulations to Dr
@imartincorena
for receiving the prestigious Dr Josef Steiner Cancer Research Award 2023 for his pioneering research into the development of
#cancer
🎉
Find out more about the award and the work it will enable, here ⤵️
Applications for the BioData Developers Network Future Innovators Mentorships are open 📢
For graduates and final-year undergraduates from 136 countries who are interested in pursuing a
#computation
or
#Bioinformatics
career.
🗓️Monday 15 April '24
We recruit talented scientists and software developers from around the world to deliver our science and make the UK a global leader in genomics. We need an immigration system that allows us to recruit the best and brightest.
The Sanger Prize offers undergrads from low and middle-income countries the chance to spend 3 months with a research group at the Sanger Institute, with travel, living and research expenses covered. Find out how to apply for our 2019 Prize
#SciencePrize
Providing new insights into how blood and immune systems develop in the first 17 weeks in utero, scientists have created the human developmental liver cell atlas
#HumanCellAtlas
#StemCells
We are delighted that Alan Turing and his science will be celebrated as the new face of the £50 note.
We were also thrilled that our namesake Fred Sanger was shortlisted for this honour, for his pioneering contributions to our understanding of genetics
#ThinkScience
We are thrilled to be part of the
@uk_biobank
Whole Genome Sequencing collaboration to sequence 500,000 human genomes, powering the next wave of genetic and health research
#HoHoHighlights
#Genomics
🧬 Determining the order of four letters of DNA has transformed how we understand life on Earth 🌍
We’re reflecting on what followed the Human Genome Project for the Sanger Institute, and what the future holds 🔮
#HumanGenome20
It’s
#AdaLovelaceDay
! We asked some of our software developers and bioinformaticians which
#WomenInTech
inspired them 👩🏻🔬👩🏽🔬👩🏿🔬
Find out who they said on our blog ⬇️
Today we celebrate our 26th anniversary! Many congratulations and thanks to all of our staff, collaborators and friends from the past 26 years.
Here’s to the next 26!
As a sequencing hub for the national
@CovidGenomicsUK
effort, we’re often asked how many
#SARSCoV2
genomes we sequence. These are the numbers, as of this week ⤵️
Check out our blog for more info on the data ➡️
#COVID19
Cancer is, at its core, a genomic disease. The hunt for the precise DNA changes that turn a healthy cell into a cancerous one has led to new understanding and new treatments.
@cosmic_sanger
#CancerGenomics
#BigData
Today marks the next chapter in the UK’s relationship with Europe. Whatever the outcome of Brexit, we will remain open and welcoming to scientists and students from around the world.
#ScienceIsGlobal
#Brexit
@embl
@TheCrick
@emblebi
By resurrecting a 50,000-year-old gene sequence, scientists have uncovered how the world’s deadliest
#malaria
parasite jumped from gorillas to humans
@MIVEGEC
#Plasmodium
We’ve just read our 5,000,000,000,000,000th base. In fact, by the time you’ve finished reading this sentence, our sequencing machines will have read another 273 million
#DNA
bases.
#5petabases
#Sequencing
the
#DNA
of 1.5 million species - all known animals, plants, fungi & protozoa on Earth - is estimated to cost $4.7bn. This is less than the cost (in today's money) that it took to sequence just one human genome.
#EarthBioGenome
#SequencingLife
Government proposals to increase the immigration health surcharge will have a detrimental impact on UK & global science.
International collaboration is vital for research and innovation.
The UK has one of the most expensive immigration systems globally, putting science at risk.
As a sequencing hub for the national
@CovidGenomicsUK
effort, we’re often asked how many
#SARSCoV2
genomes we sequence. These are the numbers, as of this week 🧬⤵️
Check out our blog for more info on the data ➡️
#COVID19
#Organoids
are clusters of cells that resemble miniature organs and are becoming commonplace in research, giving researchers a way to mimic how conditions such as cancer and
#CysticFibrosis
affect cells.
Learn more on our blog ⬇️
We are delighted to welcome Prof Ben Lehner to
@SangerInstitute
this week
He joins the Human Genetics Programme & will be using high-throughput experiments and AI to lay the foundations for programmable biology and protein engineering
Find out more ⬇️
We have sequenced over 240,000 human genomes in a record 3.5 years, for the
@uk_biobank
project🧬
The data will be available, together with health info, for researchers studying diseases like
#cancer
and
#diabetes
Find out more 👉