Glad to share this online: we’ve expanded our transcriptomics meta-analysis of heart failure to the multicellular level. Check out how you can use this reference to support your own data analysis! This was another rewarding team effort w @roramirezf94 #HeartFailure

Organoids have incredible potential in drug discovery and disease modelling. In this Scientific Computing World interview, @Iguaracysousa discusses organoid construction, nanobots, and how bioinformatics is transforming biomedical research. https://t.co/5iyI549Mo5

We are looking for a PostDoc with strong computational expertise to join our lab with a focus on computational tissue biology: https://t.co/LE55mFesUj

We use Multiome and HiC to build a comprehensive single cell variant to enhancer to gene map for coronary artery disease. Join effort with @PaulChungrohLee and IttaiEres in Nate Stitziel Lab and in collaboration with @Amgen @WUSTLmed https://t.co/bM6RPUcUEW

Excited to share our study on spatio-temporal reconstruction of cardiac scar formation led by @ChanAndyson. We combine scRNA-seq with spatial transcriptomics to resolve the fibrotic niche and the niche of dedifferentiating cardiomyocytes. https://t.co/LHlktVYU4W

Our work with @schirmerlab in multiple sclerosis (MS) is out today in @NatureNeuro. We investigated lesion progression and cell-cell communication events in MS using snRNA-seq and spatial transcriptomics 🧠 See below ⬇️ https://t.co/j6LIwv4IgU

📢 Introducing CORNETO: a unified, knowledge-driven framework for multi-sample network learning & modeling via constrained optimization, supporting a wide variety of network methods and prior knowledge 💻Code: https://t.co/OuM9Acrs9U 📜Paper: https://t.co/XFjEbKMAAL 🧵👇

Are you interested in sc-spatial multiomics data, motivated by improving patient outcomes in lung cancer, and keen to join a young and growing lab taking single-cell atlassing to clinical applications? Please apply :). We're looking for Postdocs! https://t.co/l3iEgt1gIB

Check out our work on fibroblast activation patterns in HF models! Huge thanks to my co-lead @LauraWienecke 🙏 from @LeuschnerLab!

🚨 We are looking for a PhD student 🚨 to join the Tanevski Lab and @DenisSchapiro Lab at the Heidelberg University Hospital, working at the intersection of machine learning and spatial omics as part of the Translational Spatial Profiling Center. Please RT

Congrats Julio!!

We welcome Julio Saez-Rodriguez @JulioSaezRod as our new Head of Research! Associate Director for EMBL-EBI Services Jo McEntyre @jomcentyre has been promoted to Deputy Director of EMBL-EBI & Rolf Apweiler is stepping back to Associate Director as he looks towards retirement.

See this great perspective by @roramirezf94 and others on multicellular processes and how to study them using single cell omics!

1) Are you interested in computational approaches to study the immune system 🔎🦠by integrating single-cell + spatial multi-omics data with prior knowledge? Check our review 📖out now in @NatImmunol https://t.co/ilWxyshOLR 🧵

Our @jan_lanzer will present his work (together w @roramirezf94) on multicellular programs in heart failure at #EMBOCardioBiology this week. Come find him if you are interested in how we can leverage public single cell atlases to study coordinated events in myocardial remodeling

Super excited to organize a local site for this @nf_core hackathon with @kubranarci in Heidelberg. Hoping to see many of you code some @nextflowio with us there 🤩✨🧑‍💻!

Multicellular Factor Analysis is now fully available in @eLife's website, including the editor's evaluation and our updated revision. Estimate multicellular programs and perform unsupervised analysis of samples from cross-condition single cell atlases https://t.co/K4BI3OFZ03

🧬Explore disease at a multicellular level, capturing variations in patient samples across cell types, tissue features, studies, and technologies with Multicellular Factor Analysis, peer-reviewed by @ReviewCommons and now published @eLife https://t.co/bRVOBdptFm

Thx @ERC_Research for funding our #ERCSyG project w @ejvillablanca @ZellerGroup @giacomello_lab 🙏. Looking fwd to synergizing our expertise in immunology, #spatial techs, microbiome🦠 & computational modeling💻 to study gut host-microbiome interactions in health & disease

Check out our new preprint🥳 We focused on using #gutmicrobiome 🦠data to predict heart 🫀failure risk with @erawijantaript @openreslabs @JulioSaezRod @saezlab @LevinsonLab...