Judith Simcox PhD
@JudithSimcox
Followers
3K
Following
21K
Media
191
Statuses
2K
Associate Professor @UWBiochem studying lipid signaling and regulation | Co-Director Biotechnology Training Program (BTP) | HHMI FHS
Madison, WI
Joined November 2018
Thrilled to have our story on the regulation of lysosomal lipids out in @Cell_Metabolism! The work was led by two outstanding grad students @_JessDavidson and Raghav Jain probing mechanistic control of energy expenditure @HHMINEWS @UWBiochem.
New! Online now: Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV
16
21
136
RT @JayXiaojunTan: Huge congratulations to Haoxiang & Jeff, our very first students, on publishing their exciting work! 🎉 A milestone for t….
0
6
0
RT @LammingLab: We are looking to fill the shoes of our lab manager/technician who is starting medical school Monday! If you know someone w….
0
16
0
RT @TVerkerke: I’m thrilled to share that I’ve started my lab at @UMN_IBP! The lab will study bioenergetic consequences of choline metabol….
0
9
0
RT @WeiWei_Stanford: The Wei Lab is officially up and runningđź‘Ź @longlabstanford @JudithSimcox @UWBiochem @uwmadisonipib .
0
19
0
RT @WalterWChen1: Our paper on discovering a new paradigm in peroxisome biogenesis and PEX39 (1st human peroxisomal biogenesis protein fou….
nature.com
Nature Cell Biology - Chen et al. show that PEX39 cooperates with PEX7 in the peroxisomal import of proteins containing a PTS2 site and uncover an (R/K)PWE motif in PEX39 and PEX13 that binds to...
0
28
0
RT @WARF_News: Meet Ci Ji Lim, assistant professor of @UWBiochem @UWMadisonCALS, whose long-term goal is to understand how mammalian telome….
warf.org
“CJ’s issues with cryo-EM sample preparation were not unique to him, and the solution he invented will have broad applicability in this method of growing use.”
0
5
0
RT @cell_club: Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway | Nature Communications
nature.com
Nature Communications - Cholesterol sensing by LYCHOS regulates mTORC1 signaling through GATOR1-Rag GTPase. Here, authors reveal cryo-EM structures of LYCHOS in various states, showing cholesterol...
0
8
0
RT @KatsuFunai: We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a n….
0
45
0
RT @acypess: Essential reading from @DenisPBlondin and colleagues. The thoroughness of the physiological studies is remarkable.
0
3
0
RT @DrRGJonesLab: The Jones lab is recruiting for a second opportunity @VAInstitute to study the metabolic underpinnings of autoimmune dise….
0
16
0
RT @Mel_McDowell22: Proud to share our first lab pre-print: “SND3 is the membrane insertase within a fungal multipass translocon” where @Tz….
0
11
0
Congratulations to Barbara Kahn for receiving the Roy O. Greep Award for Outstanding research. Nominated by @KajimuraLab.
2
1
7
If you’re at #ENDO2025, Come see our session on NIH/NIDDK 75th year celebration of Adipocyte Biology starting today at 4:30pm. Silvia Corvera, Annabel Wang, JoAnn Manson, Yu-Hua Tseng, Lori Zeltser, and I will be speaking.
2
1
14
RT @neuroadipo: Headed to #ENDO2025 this week? Come see us hypothalamic neurogenesis folks! Chaired by @KurraschLab, with me, @DavidPetrik7….
0
6
0
RT @CellPressNews: Discovery of peptides as key regulators of metabolic and cardiovascular crosstalk. Check out this review in @CellReports….
cell.com
Zhang et al. highlight the role of peptides in crosstalk and metabolic processes. They discuss the history of peptide discovery and recent advances in peptidomics, proteomics, and AI technologies...
0
21
0
RT @Ge_Lab_UW: Check our our recent collab in @NatureCVR ! Congratulations & many thanks to Ieng Lam Lei & @PaulTangMD for the opportunity….
0
1
0
Officially tenured. Thank you to all the mentors who guided me, and to the trainees who made this possible with your ideas, hard work, and scientific joy.
29
12
191
Because acylcarnitines are known to regulate insulin sensitivity and energy expenditure, it will be exciting to explore these pathways with the various SCD models. Finally, it was an honor to co-correspond with James Ntambi, a leader in lipid signaling and metabolism.
0
0
2
Great work by Mugagga, @LainyVonBank and @_JessDavidson from the Simcox Lab! SCD1 is known to regulate the production of monounsaturated fatty acids and development of diabetes in response of high carbohydrate diet. We showed loss of SCD1 also controls acylcarnitine levels.
Research from the James Ntambi and @JudithSimcox Labs reveals an enzyme’s important role in maintaining a healthy balance of lipids in our bodies. More on their latest research:
1
5
21
RT @UWBiochem: Research from the James Ntambi and @JudithSimcox Labs reveals an enzyme’s important role in maintaining a healthy balance of….
biochem.wisc.edu
Research from the Ntambi and Simcox Labs reveals an enzyme’s important role in maintaining a healthy balance of lipids in our bodies.
0
4
0