I am grateful and excited to share this work. MscK is a beautiful protein - working with it has been a joy. Congratulations to my supportive coauthors, mentors, and friends who made this possible @YuanLabWUSTL, Grigory Maksaev (WUSTL), Brock Summers (WUCCI), and @JAJFitzpatrick.

First they came for the Immigrants. And I wrote a memo. Then they came for trans people. And I wrote a memo. Then they came for the comedians. And I wrote a memo. Then they came for me. And there was no one to write a memo for me.

Fixed it: --> last year, the U.S. sold more educational services to the rest of the world than it sold in natural gas and coal **combined** --> every $1 of research funded by NIH generates $2.56 in economic activity --> more than 1.1M foreign students come to the U.S. each year

Oh please. There’s a lot of room for improvement at the NIH, but its entire budget is less than 1% of total federal expenditures in 2024.

Dear Ion Channel and Structural Biology friends - I'm moving over to Bluesky! I'll still be here from time to time but plan to be more active over there (jmount@bsky.social). Catch you on the flipside!

Two of the most qualified women in the country ran for president against an unqualified, racist game show host who had a history of committing fraud and sexual abuse. And the country was basically split 50-50. That should tell us some things.

Happy Halloween!

This meme is a joke but also life-changing advice if taken to heart

If Billionaires like Jeff Bezos and Elon Musk don't want Kamala Harris to win, maybe she's actually good for people who aren't billionaires.

Collaborative work of @slavicaPD, @Hashemyaser4, Jovanovic Lab and @DjuranovicLab - a new method to isolate ribosomes and translational material in minutes. We show multiple usage of our RAPPL method in biochemical and structural assays with ribosomes. Please be free to contact

Wonderful news! Parafilm M rules! Very well-deserved recognition after helping so many other #NobelPrize winners achieve their breakthroughs! Congratulations @ParafilmM

Excellent thesis defense by Dr. Gao! Congratulations Jian, we are very proud of you! 🥳

My PI: So, do you have a plan? Me: I have concepts of a plan My PI:

Conformational change in transitioning from the inactive UvrD1 monomer-DNA structure to the leading subunit of the activated UvrD1 dimer-DNA structure. https://t.co/LIEhbapyms

Congratulations to Drs. Irfan Lodhi, Jeffrey Millman, Maria Remedi, and Julie Silverstein on achieving full professorship in their careers! Learn about each of their journeys: https://t.co/tikXeoPGLY. @JeffreyRMillman @LodhiLab @WUDeptMedicine

Nature research paper: Signatures of magnetism control by flow of angular momentum

Any sufficiently advanced research project is indistinguishable from a drunken walk.

@ChandaLab06 @JonathanMount6 @YuanLabSinai A huge shoutout to my 'partner in crime' @JonathanMount6 and the invaluable contributions of Jian Huang, @johncowgill11, Yongchang Chang, Kathleen Bickel, the @YuanLabSinai, and the Jianhan Chen lab at UMass. I’ve learned a lot from these amazing people!

The open state was certainly tricky to capture and revealed more than a few unexpected features! Happy to have played a role. Thanks and congratulations to @veburts @ChandaLab06 @YuanLabSinai @johncowgill11, Yongchang Chang, Jianhan Chen and Jian Huang, and Kathleen Bickel

A pervasive view is that TRP channels represent primary sensors of mechanical forces. Along with @PooleLab1 and @BorisMartinac we reviewed the evidence supporting this in @TrendsBiochem

First structures that illustrate opening of wild-type human TRPV3 (no sensitizing mutations!) by agonists, 2-APB or THCV, acting through different binding sites and expelling lipid from the vanilloid site. @knadezhdinPhD @arthurCantab @IrinaTalyzina https://t.co/rWltNPZUbZ