Deepanjali Dwivedi, PhD
@Deepanjali25
Followers
246
Following
884
Media
0
Statuses
216
Scientist I at Allen Institute for Brain Science. Former post-doc in Gord Fishell's lab at Harvard Medical School and the Broad Institute.
Seattle, WA
Joined March 2017
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests. By @OliviaGieger
https://t.co/kezWjarq2k
thetransmitter.org
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.
0
8
24
Ever feeling like that when you're doing your conference presentations?
19
421
2K
One of the most fun collaborations I ever had. Thanks @GPouchelon and @GordFishell for giving me the opportunity to contribute to this study. Congratulations to all the authors who made this paper possible.
1
4
15
Huge effort from our team @AllenInstitute. A suite of enhancer AAVs and transgenic lines for targeting cortical cell types.
A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types https://t.co/e0yhFnmCdm
#biorxiv_molbio
0
2
11
Neurogliaform cells are probably the least studied type of interneurons. My dear lab mate @Su_hang_ has spearheaded the study performing in vivo two-photon imaging of these interneurons, capturing them in action during visual stimuli and locomotion.
A big shout out to @Su_hang_ for her amazing work with me and @LeenaAIbrahim , in identifying and studying the role of neurogliaform interneurons in V1 cortex. Come read about how these regulators of cortical function act in different cortical layers!
0
1
7
A big shout out to @Su_hang_ for her amazing work with me and @LeenaAIbrahim , in identifying and studying the role of neurogliaform interneurons in V1 cortex. Come read about how these regulators of cortical function act in different cortical layers!
biorxiv.org
Neurogliaform cells are a distinct type of GABAergic cortical interneurons known for their ‘volume transmission’ output property. However, their activity and function within cortical circuits remain...
1
15
86
Happy to share our new J Neurosci paper, showing how mediodorsal (MD) thalamus engages CCK+ interneurons to evoke CB1R-sensitive feed-forward inhibition in L3 of prelimbic prefrontal cortex (PFC), led by @aichurokkamal, @kmanoocheri, and @theXL92: https://t.co/aksHMgmuCb
jneurosci.org
Interneurons in the medial prefrontal cortex (PFC) regulate local neural activity to influence cognitive, motivated, and emotional behaviors. Parvalbumin-expressing (PV+) interneurons are the primary...
1
17
64
Our paper just came out in @Nature. Congrats to everyone involved, and thanks to our amazing collaborators/former mentors @TonyZador @JesseAGillis Stephan Fischer, and Patrick Kanold.
nature.com
Nature - BARseq interrogates the expression of 104 cell-type marker genes in 10.3 million cells over nine mouse forebrain hemispheres to reveal the role of peripheral inputs on cortical area...
5
20
118
The Fishell lab https://t.co/67Mk53XbAa
@GordFishell at the Broad Institute @broadinstitute is hiring a computational associate. You will work with scRNAseq, scATACseq, spatial transcriptomics and more to learn about interneuron and developmental neurobiology! Please DM me/RT!
fishelllab.hms.harvard.edu
0
11
18
We're still not over this beautiful double cover for the October 13 issues of @ScienceMagazine and Science Advances! 😍🧠 Credit: Ivana Kapustová and Sten Linnarsson, The Karolinska Institute with the Allen Institute for Brain Science
1
23
76
Extremely excited about the beta release of our brand-new Allen Brain Cell (ABC) Atlas web portal! Currently it includes an scRNA-seq dataset & a MERFISH dataset, each with ~4M cells, representing ~5200 clusters in the whole mouse brain. It is based on https://t.co/Dp1PXfOC9m.
biorxiv.org
The mammalian brain is composed of millions to billions of cells that are organized into numerous cell types with specific spatial distribution patterns and structural and functional properties. An...
Introducing the Allen Brain Cell (ABC) Atlas [ʙᴇᴛᴀ] representing ~5,200 newly transcriptomic-defined cell types and their spatial locations across the whole mouse brain. 🧵 Access ABC Atlas data visualization & pre-publication #openscience datasets: https://t.co/7ogBtSMb14
5
113
364
For those of you who may have missed it, here is a new paper on the surprisingly selective connectivity of cortical somatostatin cells that we just published in @NeuroCellPress ! @JJSherryWU @elaine_sevier
3
40
201
Brain imaging without compromise. ✨🔬 Using technology originally designed for defect detection in electronics manufacturing, the ExA-SPIM microscope is showing scientists the brain as it’s never been seen before. Look into the future of #microscopy at https://t.co/MrYDZQmrO6
6
103
363
Our own @HongkuiZeng has been elected to @theNASciences! She was chosen for her contributions to society's understanding of mammalian brain cells and connections, and leading the development of #OpenScience data and tools.
We are thrilled to announce the election of 120 members and 23 international members to the National Academy of Sciences in recognition of their distinguished and continued achievements in original research. https://t.co/Uei58ej6WI Congratulations to our new #NASmembers! #NAS160
0
6
12
So after a 3 year revision, @LeenaAIbrahim 's take on how activity and Nova2 interact to direct synaptogenesis in SST interneurons. This is definitely a case where the reviewers comments helped. Hopefully published shortly in a peer-reviewed journal!
biorxiv.org
Somatostatin interneurons are the earliest born population of cortical inhibitory cells. They are crucial to support normal brain development and function; however, the mechanisms underlying their...
3
7
84
Our paper is now online! Thank you @3RakeshMishra for everything and @shubhanshupande for lovely help. Also, a big thanks to @intron2exon, @binitaghosh12, Mandar Naik for providing the outstanding support during the project. Work explained in thread: @ccmb_csir @CRISPR_News 1/n
11
12
75
https://t.co/LRFAoKK7Rk We @GaitiHasan @TheCoffeeNeuron report transgene- & feeder- free iPSC lines from a 21y old PLA2G6- Parkinson's patient & control @NCBS_Bangalore. Thanks to @BijuViswanath13, Dr Sanjeev Jain @NIMHANS_BLR for the patient samples,@India_Alliance for funding
16
7
58
Very happy to share my first preprint showing a role for an insula-amygdala pathway in aversive signaling during fear learning. Cheers also to all my talented colleagues and co-authors!
An insular cortex to lateral amygdala pathway in fear learning https://t.co/OUJyZ2PFV1
#biorxiv_neursci
1
5
31