Hongkui Zeng
@HongkuiZeng
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Director of Allen Institute for Brain Science
Joined April 2020
Scientists at Allen Institute for Brain Science led the efforts in generating the largest electron microscopy volume of the brain ever and reconstructing the beautifully intricate wiring diagram of the mouse visual cortex. Congratulations to team for this spectacular achievement!
How does the brain work? Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. đź§µ
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It was a great pleasure to discuss why and how to study cell types in the human brain on The Transmitter.
The single-cell omics revolution is changing how we study the brain. Brain Science EVP and Director @HongkuiZeng and Sr. Investigator Ed Lein share how these tools have changed neuroscience and what's next in a new perspective piece in @_TheTransmitter.
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We can't stop aging, but can we slow it down? 🎧 @DrTorahKachur discusses our recently published aging mouse brain research examining cell types & brain regions involved with aging with @HongkuiZeng on @CBCRadioActive. This research could help scientists target effects of aging.
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Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice https://t.co/akavz0aal0
@HongkuiZeng @Nature @BosiljkaTasic
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Hallmarks of brain aging from a comprehensive single-cell sequencing of 1.2 million cells Specific cell-type pattern, role of immune response, inflammation, and a potential hypothalamus (near 3rd ventricle) hot spot for aging https://t.co/EZv7j1VjwU
@Nature @AllenInstitute
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Excited to share our single-cell study on aging mouse brain published in Nature today! We found an aging hotspot in specific hypothalamic cell types involved in energy homeostasis, which show both decreased neuronal function and increased immune responses.
nature.com
Nature - A comprehensive single-cell RNA sequencing study delineates cell-type-specific transcriptomic changes in the brain associated with normal ageing that will inform the investigation into...
New brain aging study is out today in | @Nature The largest single-cell RNA seq dataset of mouse brain aging reveals incredible insights and could pave the way for future therapies to slow or manage the impacts of the aging process. đź§µ #studyBRAIN
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The BRAIN Initiative has driven unprecedented progress in neuroscience, but a 40% funding cut threatens this momentum. Restoring funding would help solve more mysteries of the brain and developing life-changing treatments. #studyBRAIN
nature.com
Nature Neuroscience - Launched in 2013, the BRAIN Initiative (BRAIN) in the United States aimed to unlock the mysteries of the brain and develop new treatments for neurological and neuropsychiatric...
The BRAIN Initiative has been an engine of innovation but is now fighting for its survival. Here we discuss why BRAIN is special and why we must all fight for it now https://t.co/1SECiT2G7m
@TheHongLab @DrZoePhD @bjmarlin @doristsao @moriel_z @HongkuiZeng XiaokeChen ZivWilliams
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Have you used @AllenInstitute datasets, atlases, protocols, mouse lines, and other #OpenScience resources in your research or classroom? Tell us about it! Share your story at https://t.co/C4Iw9P4SC8. Select stories will be shared on our social media channels in #OpenScienceWeek.
alleninstitute.org
Have you used our open science resources to support your research or curriculum? We want to hear from you!
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Looking forward to welcoming renowned neurologist and neuroscientist @luscherc to the @AllenInstitute! If you are in the Seattle area, I hope you will join me on July 31, 5pm for what will be an illuminating presentation on the neuroscience of fentanyl addiction.
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Thanks @theNASciences for highlighting the open science we do at @AllenInstitute that has transformed neuroscience research and discovery!
As we honor #WorldBrainDay, we are highlighting #NASmember Hongkui Zeng (@HongkuiZeng) of @AllenInstitute. In a new Q&A, she explores the impact of her efforts to generate open-access datasets and tools to accelerate #neuroscience discovery. đź§ Read here: https://t.co/PT1q3QQMR6
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“The brain’s complexity and diversity surprised us,” recalled @HongkuiZeng @AllenInstitute. She and a network of researchers charted a colorful cellular map of the mouse brain, shedding light onto thousands of cell types and their intricate connections. https://t.co/HjMvcFi0aR
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To everyone who has been shocked and depressed by the staggering 40% cut to the BRAIN Initiative: we have a voice! Outside Witness Testimony (aka written testimony) for the FY 2025 appropriations cycle is ongoing. Deadline for the House side is Friday May 3 and the Senate side
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Vision plays a key role in the developing human brain. 👀🧠New @Nature study finds that a loss of sight led to major reorganization of brain cell types within the visual regions and across half of cortex. https://t.co/DPrbe61WCV
alleninstitute.org
Nature study reveals the key role vision plays in shaping the brain’s mosaic of neurons.Â
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We're excited to announce our two keynote speakers this year! We're thrilled to have both @DaphneKoller of @insitro and @HongkuiZeng of @AllenInstitute delivering keynote talks at SBI2 2024! Stay tuned for registration and abstract submission details!
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We are entering the 7th year of our Next Generation Leaders (NGL) program! I have constantly been amazed by these NGLs - they are not only brilliant, creative scientists but also incredibly kind and genuine human being. Treasure the lasting bond with them! Hope you will join us!
Open call for Next Generation Leaders! Our NGL program recognizes early career scientists with fresh and innovative perspectives. For 3 years, NGLs contribute to ongoing research and initiatiatives at the Allen Institute. Apply by June 5:
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"A colorful mosaic that maps the positions and roles of cells in the mouse brain offers insights into its functional complexities." ✍️ Laura Tran for @TheScientistLLC
https://t.co/RoMtTyqpTX
the-scientist.com
A colorful mosaic that maps the positions and roles of cells in the mouse brain offers insights into its functional complexities.
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Explore the complexity of the first complete cellular map of the adult mouse brain in our new interactive, multimedia article: https://t.co/sJgRSx0UWF
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A view from @NINDSdirector , Dr. Walter Koroshetz, on the importance of the @BrainInitiative for understanding and treating brain disorders: BRAIN at 10: A View from the National Institute for Neurological Disorders and Stroke https://t.co/UQkdOjmp2w
#NINDS
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It was an honor to join brilliant minds from @AllenInstitute, @ChanZuckerberg, and @UofWA to celebrate #SeaSynBio and this cross-institutional effort to deliver new insights and technologies to record the history of cells over time.
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TOMORROW - join our Reddit AMA with neuroscientists @HongkuiZeng and Ed Lein! Kick off #BrainWeek by asking your burning questions about brain mapping and brain diseases. 📆 Mar. 11, 2:30-4:30pm Pacific 📍r/AskScience: https://t.co/UwqQwCIK8e 🔗 More: https://t.co/7SsKsd8JsE
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