Paras Verma, Ph. D
@parasvcb
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Computational Biologist, Research fellow at IISER Mohali
Joined May 2012
Glad you like it! It's the nano-protein-viewer that I built over the summer Really need to work on marketing lol
@stevenyuyy Whoa what plugin is this? So much prettier than protein viewer
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UFβs Perez Lab Gators team wins international AI protein design competition https://t.co/5GTPa9ZZk0
@UFChemistry
news.clas.ufl.edu
The Perez Lab Gators aim to produce high-impact, reproducible science through physics- and AI-based tools to improve human health.
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RUNX1C isoform identified as driver of chemoresistance in acute myeloid leukemia - ... a way to potentially disarm it. In findings newly published in Blood Cancer Discovery, a team led by JAX assistant professor Eric Wang reports onΒ ... -
news-medical.net
One of the biggest challenges in cancer treatment is that certain cancers reappear after chemotherapy-and an aggressive type of blood cancer called acute myeloid leukemia (AML) is notorious for this.
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Thank You @biopatrika for featuring my work! Grateful to @ChabaRachna!
#authorinterview Dr. Swati Singh @swatisingh2511 working with Prof Rachna Chaba @ChabaRachna at IISER Mohali @IiserMohali talks about her work on "Decoding the impact of genetic variations in DgoR on D-galactonate metabolism" @JBacteriology @ASMicrobiology
https://t.co/d64iaWSGcZ
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Happy to share our latest publication in Scientific Data @ScientificData on genome assembly and annotation of Nasonia oneida, the youngest species in the jewel wasp complex. @IiserMohali @DBS_IISERM
https://t.co/YwoWBWCafD
nature.com
Scientific Data - Genome assembly and annotation of the parasitoid jewel wasp Nasonia oneida
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Postdoc position in our group at @emblebi , analyzing single cell data to better understand and treat neurodegen diseases, collab with @AndrewBassett43 , @mo_lotfollahi, @bayraktar_lab M Strauss and others @OpenTargets . Deadline 20/07. Please shareπ:
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This is absolutely terrible. The benefits that those tools have brought to the scientific community are incommensurable.
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Thrilled to see #SAVANA out in @naturemethodsπ₯³ SAVANA detects haplotype-resolved somatic SVs and copy number aberrations (SCNAs) and infers tumour purity & ploidy in clinical samples using long-read sequencing with or WITHOUT a matched germline control π https://t.co/AdZhqHUsDb
nature.com
Nature Methods - SAVANA is a tool to detect somatic structural variants and copy number aberrations using long-read sequencing data, offering high sensitivity, specificity and compatibility with or...
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Deep-learning-based single-domain and multidomain protein structure prediction with D-I-TASSER @NatureBiotech οΌοΌD-I-TASSER is a hybrid deep-learning and physics-based pipeline that outperforms AlphaFold2 and AlphaFold3 in both single-domain and multidomain protein structure
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"Only diamonds are made under pressure; good scientists are made with love and support." https://t.co/F77h4I6XYR
elifesciences.org
An eLife survey explores the experiences of those in the research community who support colleagues struggling with their mental health.
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𧡠You filtered your VCF. But the output broke your pipeline. Why? You didnβt keep the header. Let's fix that.
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New Online! Uncovering mRNA sequences that control translation initiation https://t.co/nfH6licvtD
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A highlight of our recent research article by @_AndrewLeduc et al. https://t.co/3385ua1gGj
azolifesciences.com
A new study in Nature Communications presents a solution to protein leakage in single-cell proteomics, improving data quality by identifying and excluding permeabilized cells using a machine learning...
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New online! RNA splicing β a central layer of gene regulation
nature.com
Nature Reviews Genetics - Technological and computational advances in recent years, from cryo-electron microscopy to sequencing technologies and machine learning, have substantially deepened our...
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πͺ What if we could map muscle repair pixel by pixel? π¬ Our group leader Dr @Wi_Roman (@ARMI_Labs) built a low-cost spatial transcriptomics platform to do just that - revealing how muscles heal, grow & communicate. It's reshaping regenerative medicine. https://t.co/jZ3jMEosA6
emblaustralia.org
Dr William Roman, an EMBL Australia & Baker Foundation group leader at the Australian Regenerative Medicine Institute (ARMI), is reimagining the future of muscle repair β one pixel and protein at a...
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14/14 π’ We welcome feedback, queries, and collaborations! Tag us or email to explore how ENACTdb can support your work. π Method paper: https://t.co/1v48SjPflm π DB paper: https://t.co/5rKVv1Nkv9
#AlternativeSplicing #Transcriptomics #Bioinformatics #Proteomics
academic.oup.com
AbstractMotivation. Gene transcripts are distinguished by the composition of their exons, and this different exon composition may contribute to advancing p
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13π Acknowledgments Thanks to my supervisor Dr. Shashi Pandit ( https://t.co/aO2jgJIJnB) for his constant mentorship. Also grateful to co-authors @Deeeksha_Thakur & @Deepanshi_awast for building the algorithm, DB, and analysis! Supported by @DBTIndia & @IiserMohali
#TeamScience
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12/14 π» Try ENACTdb now and find functional insights like: β’ Polymorphic attributes of exons β’ Mapping exonic variation to protein domains β’ Detecting how splicing reshapes protein features β’ Identifying indels/substitutions from exon changes. π
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11/14 𧩠Why use ENACT/ENACTdb? ⒠Explore how splicing/transcriptional choices diversify the proteome ⒠Understand how splicing architecture impacts local/global protein changes ⒠Functional genomics, disease variant interpretation, evolution studies
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10/14 π ENACTdb: Data for the community and features! We annotated genes across 5 model organisms (human, mouse, zebrafish, fly, worm). ENACTdb enables: β’ Gene-based search (name or Entrez ID) β’ Exon-to-protein feature mapping (Pfam, structure, disorder) β’ Isoform comparison
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