Nature Reviews Molecular Cell Biology
@NatRevMCB
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A Reviews journal from @SpringerNature . Timely Review articles, Comments and Highlights of the latest research in molecular cell biology.
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We've just published a tour-de-force Review on the metabolic regulation of skeletal muscle in response to exercise 💪🏼🏃🏾
Fantastic effort by the authors:
@JonoSmith01
@KevinMurachPhD
@DyarKen
@JuleenRZierath
This Review is free to access for 30 days!
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432
Now Online Lysosomes as coordinators of cellular catabolism, metabolic signalling and organ physiology
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405
Now Online Challenges and directions in studying cell–cell communication by extracellular vesicles
1
121
392
Now Online The molecular basis of translation initiation and its regulation in eukaryotes
0
105
384
Now Online Cell cycle control in cancer
3
68
303
Now Online Global view of human protein glycosylation pathways and functions
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120
305
Now Online CRISPR technologies for genome, epigenome and transcriptome editing
2
76
300
Now Online The assembly, regulation and function of the mitochondrial respiratory chain
4
85
298
Now Online Organization, dynamics and mechanoregulation of integrin-mediated cell–ECM adhesions
1
68
292
Now Online Energy-driven genome regulation by ATP-dependent chromatin remodellers
0
74
273
Now Online Roles of mRNA poly(A) tails in regulation of eukaryotic gene expression
2
74
275
Now Online A guide to membraneless organelles and their various roles in gene regulation
0
93
272
Now Online The principles of directed cell migration
0
72
265
Now Online Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2
67
265
Now Online Revolutionizing DNA repair research and cancer therapy with CRISPR–Cas screens
0
59
256
Now Online A guide to cell death pathways
1
78
259
Now Online Transcription regulation by long non-coding RNAs: mechanisms and disease relevance
1
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249
Now Online The molecular basis for cellular function of intrinsically disordered protein regions
1
66
245
Now Online MicroRNA-mediated regulation of glucose and lipid metabolism
2
53
236
Now Online Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases
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50
238
Now Online Mechanisms of SARS-CoV-2 entry into cells
3
79
227
Now Online Cell–extracellular matrix mechanotransduction in 3D
0
64
219
Now Online Intracellular mRNA transport and localized translation
2
50
215
Now Online The cell biology of ferroptosis
2
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Now Online A guide to machine learning for biologists
1
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Now Online The expanding world of tRNA modifications and their disease relevance
0
60
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Now Online Mechanical regulation of early vertebrate embryogenesis
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Now Online Co-transcriptional gene regulation in eukaryotes and prokaryotes
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Now Online Quality control of the mitochondrial proteome
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Phase separation is hotter than ever! Don't miss out on the Review by Hyman & Rosen -- read the full article:
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Now Online Mechanics and functional consequences of nuclear deformations
1
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199
Now Online Control of satellite cell function in muscle regeneration and its disruption in ageing
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Now Online Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2
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Now Online Molecular mechanisms of dietary restriction promoting health and longevity
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Now Online Nuclear compartmentalization as a mechanism of quantitative control of gene expression
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Now Online The roles of histone variants in fine-tuning chromatin organization and function
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178
Now Online The aetiology and molecular landscape of insulin resistance
0
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Now Online Fibroblast and myofibroblast activation in normal tissue repair and fibrosis
1
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Now Online ncRNA regulation of mitochondrial transcription
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Now Online Ubiquitin ligases: guardians of mammalian development
0
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Now Online The physiology of alternative splicing
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Now Online Re-evaluate evaluation letters — set scientists free!
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A great read: Review by Statello, Guo, Chen & Huarte on Gene regulation by long non-coding RNAs
#lncRNAs
#generegulation
@MaiteHuarteLab
@CIMA_unav
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Now Online The senescence-associated secretory phenotype and its physiological and pathological implications
0
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Our newest
#NRMCBReview
is now online!
🧬Revolutionizing DNA repair research and cancer therapy with CRISPR–Cas screens✂️
by
@SamahAwwad3
,
@almuseben
, John C Thomas,
@vg29029
and
@SPJacksonGroup
🔗
0
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A classic! Review on CRISPR -- know more abut this powerful tool. Full text here:
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Now Online Guidelines and definitions for research on epithelial–mesenchymal transition
0
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Now Online The plasticity of DNA replication forks in response to clinically relevant genotoxic stress
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✨New
#NRMCBReview
🥳
Control of stem cell renewal and fate by YAP and TAZ
by
@driskilljordan1
& Duojia Pan
Read here how the 🦛pathway effectors YAP/TAZ regulate stem cell function:
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Now Online Cellular and molecular mechanisms of skin wound healing
2
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Now Online Enhancer selectivity in space and time: from enhancer–promoter interactions to promoter activation
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Now Online Cellular origins of dsRNA, their recognition and consequences
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To further explore the universe of
#biomolecularcondensates
see this Collection of
#Reviews
, journal clubs and selected research articles
@NaturePortfolio
highlighting recent progress in mechanisms and roles of
#LiquidLiquidPhaseSeparation
in biology
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Fresh from press
#Review
by Henry De Belly, Ewa Paluch & Kevin Chalut discussing the cooperation between
#mechanosensing
,
#cellsignalling
and
#cellmechanics
in regulating
#cellfate
@KevinChalut
@PaluchLab
@Henry_de_belly
@Cambridge_Uni
@UCSF
0
34
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Now Online Regulation of microtubule dynamics, mechanics and function through the growing tip
0
25
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Now Online Cytoskeletal control of early mammalian development
0
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Fresh from press
#Review
by Claudio Collinet and Thomas Lecuit discussing how tissues are shaped during development - program versus self-organization
@LecuitLab
@centuri_ls
@cdf1530
#morphogenesis
#development
1
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Now Online Applications of CRISPR–Cas in agriculture and plant biotechnology
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Now Online Human topoisomerases and their roles in genome stability and organization
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New frontiers in
#mechanobiology
!
Fresh from press
#Review
by Dupont, Frezza and co. on the crosstalk between
#mechanotransduction
and
#metabolism
@SirioDupont
@UniPadova
@FrezzaLab
@MRC_CU
#cellmechanics
#cellmetabolism
1
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Now Online The molecular principles of gene regulation by Polycomb repressive complexes
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New
#Review
from
@VolkerHaucke
lab
@LeibnizFMP
on the role of
#phosphoinositides
in shaping and directing membrane dynamics
#lipidsignaling
Access FREE pdf here:
#sharedit
1
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Now Online Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids
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Now Online Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins
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Now Online Context-dependent TGFβ family signalling in cell fate regulation
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Now Online Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design
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Now Online Phosphoinositides as membrane organizers
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Now Online Mechanisms of substrate processing during ER-associated protein degradation
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Now Online Cellular and molecular mechanisms of Hedgehog signalling
0
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♨️Hot article notification♨️
Challenges and directions in studying cell–cell communication by
#ExtracellularVesicles
@DaveCarter1234
,
@guillaume_niel
@VaderPieter
Clayton Lambert & Raposo
#EVsAreCool
FREE pdf:
Full text:
2
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Featured on June cover
#Review
by Tsutomu Suzuki on
#tRNA
modifications and their roles in disease
#RNAmodifications
@UTokyo_News_en
0
34
120
The lipotype hypothesis - our newest comment from
@Gio_Dangel0
and
@GioeleLaManno
(
@EPFL
) on how membrane lipid composition impacts on signalling:
🔗
0
43
118
Now Online Long non-coding RNAs: definitions, functions, challenges and recommendations
2
46
120
Now Online Mechanisms of BCL-2 family proteins in mitochondrial apoptosis
1
44
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Now Online Autophagy and autophagy-related pathways in cancer
0
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Are you looking for a comprehensive Review on selective
#autophagy
? Tamotsu Yoshimori,
@LabYoule
and colleagues discuss the different autophagy pathways in their recent
#NRMCBReview
:
🚨
0
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Our first
#NRMCBReview
of 2023 is out now and it's a special one! John Mattick and colleagues have put together a Consensus Statement addressing the definition, nomenclature and classification of long non-coding RNAs.
Have a read here: 🔗
#lncRNA
1
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115
A must read for all
#CRISPR
enthusiasts
This time highlighting the yang: mechanisms and
#biotechnology
applications of anti-CRISPR proteins!
by Ning Jia & Dinshaw Patel
@sloan_kettering
FREE pdf available
#sharedit
0
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Now Online Immortalizing switch to OXPHOS
0
33
114
Now Online Molecular mechanisms underlying nucleotide repeat expansion disorders
1
33
115
Now Online Mechanisms of bone development and repair
0
32
107
Now Online Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics
0
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Check out our new
#Review
by Pere Roca-Cusachs
@IBECBarcelona
and Johanna Ivaska
@johannaivaska
@IvaskaLab
on Integrins as biomechanical sensors of the microenvironment
#integrin
#mechanobiology
#extracellularmatrix
#mechanosensing
#development
#cancer
0
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Now Online White adipocyte dysfunction and obesity-associated pathologies in humans
1
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Now Online Mechanisms controlling pancreatic islet cell function in insulin secretion
1
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109
In their recent
#Review
Chen And Rechavi discuss the role of small RNAs in cellular and organismal communication
#signaling
#smallRNA
@UCRCNAS
@odedrechavi
1
30
111
Celebrate
#DNAday2020
with this
#Review
by Maxim V. C. Greenberg
@maxvcg
& Deborah Bourc’his
@DeborahBourchis
@institut_curie
discussing the diverse roles of
#DNAmethylation
in mammalian
#development
and
#diseases
Access here:
1
38
111
✨ICYMI: New
#NRMCBReview
on the role of actin in mitochondrial biology, e.g., during mitochondrial fission, dysfunction and
#mitophagy
, or motility.
➡️"The multiple links between actin and mitochondria" by
@TakShunFung
,
@raj_mito
and
@hhiggslab
.
2
35
110
Now Online Pore-forming proteins as drivers of membrane permeabilization in cell death pathways
0
28
107
Now Online Regulation and functions of non-m6A mRNA modifications
0
25
108
New
#Review
by Ivana Jerkovic´ & Giacomo Cavalli
critically discussing methods for
#GenomeOrganization
analysis
#3Dgenome
#ChromatinOrganization
@giacomo_cavalli
@IGH_MTP
Full article link:
FREE pdf is here:
#sharedit
0
40
106
In July issue: the multifaceted functions of reactive oxygen species in cell biology
#Review
by Helmut Sies and Dean Jones
@EmoryDeptofMed
@HHU_de
#reactiveoxygenspecies
#redox
#cellsignaling
Access here:
1
35
105
Now Online The multiple links between actin and mitochondria
0
25
103
Now Online Patterning of the cell cortex by Rho GTPases
1
29
105
Our newest & very comprehensive
#NRMCBReview
discusses both established and cutting-edge multi-omics technologies, and the optimization of throughput and resolution, modality integration, and accuracy.
@AlevBaysoy
,
@Zhiliang_Bai
,
@RongFan8
&
@satijalab
👉🏼
0
29
104
Now online 📢 New
#NRMCBReview
🚨
@BakerLabUtah
and
@RutterLab
review the literature on how metabolites can act as signalling molecules in different cellular processes.
Read their comprehensive discussion here:
🔗
1
29
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!Conference ALERT!
Virtual
@NatureConf
on Metabolism in Health and Disease
@NatRevMCB
is organizing together with our colleagues
@NatureCellBio
and
@NatMetabolism
will be FREE to attend!
Register here:
Looking forward to it!
#NatConfMetabolism
1
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104
A must read! New
#Review
by Charles Gersbach
@DukeU
on the next generation of CRISPR–Cas technologies and their applications
#CRISPR
#genetherapy
0
48
99
Understand how cancer cells proliferate with this excellent
#Review
on
#CellCycle
control in cancer by Matthews, Bertoli & de Bruin
@DeRobertus
@helenkmatthews
@uclcancer
@MRC_LMB
#MitoticCheckpoint
0
33
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