Nature Reviews Genetics
@NatureRevGenet
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Publishing reviews and commentaries across the fields of genetics and genomics. Part of @SpringerNature and @NaturePortfolio.
London, UK
Joined September 2009
Our November 2025 issue is now live: https://t.co/B7iHUvGbKG Topics include: the impact of SVs on the 3D genome in disease; single-cell DNA sequencing of somatic mutations; the role of transcription compartments in gene regulation; synonymous mutations and their consequences
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New online! Redefining cellular reprogramming with advanced genomic technologies https://t.co/zTZ5HlhXin
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New online! Clinical use of polygenic risk scores: current status, barriers and future directions https://t.co/bCwFJXczpV
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Our November 2025 issue is now live: https://t.co/B7iHUvGbKG Topics include: the impact of SVs on the 3D genome in disease; single-cell DNA sequencing of somatic mutations; the role of transcription compartments in gene regulation; synonymous mutations and their consequences
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New online! Microorganisms as architects of a sustainable future
nature.com
Nature Reviews Genetics - Microorganisms are central to climate stability, food security and biodiversity, yet they remain absent from global sustainability frameworks. In this Comment, Nicole...
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New online! Microorganisms as architects of a sustainable future
nature.com
Nature Reviews Genetics - Microorganisms are central to climate stability, food security and biodiversity, yet they remain absent from global sustainability frameworks. In this Comment, Nicole...
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Our featured article: Structural variants in the 3D genome as drivers of disease - Review by Varun K. A. Sreenivasan, Verónica Yumiceba & Malte Spielmann https://t.co/ageiscVvgs Free to read here:
nature.com
Nature Reviews Genetics - Disruption of the 3D genome caused by structural variation contributes to developmental disorders and cancer. The authors review the causes and molecular and clinical...
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New online! Host–pathogen interactions shape human evolution and future pandemics https://t.co/1xv0hj0rfM
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1/5 Pleased to share a review in @NatureRevGenet on Clinical Use of Polygenic Risk Scores: Current Status, Barriers & Future Directions Discusses PRSs in the context of the ACCE framework (analytic validity, clinical validity, clinical utility & ELSI) https://t.co/BK52kjAX4Q
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New online! Clinical use of polygenic risk scores: current status, barriers and future directions https://t.co/bCwFJXczpV
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The authors discuss challenges, opportunities and examples in advancing spatial technologies to clinical applications, including the increasing importance of artificial intelligence, and explore possible avenues for a more comprehensive, multidimensional assessment of tissues
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This Review examines spatially resolved pathological molecular alterations in a wide range of disease processes, such as developmental disorders, tumorigenesis, neurodegeneration, infection and inflammation, through the lens of universal biological frameworks
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Spatial analysis empowers the discovery of developmental and disease-associated molecular signatures, cell states and multicellular niches, as well as the evaluation of disease heterogeneity within and across organs
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Recent advances in high-throughput spatial omics technologies have enabled the investigation of this complexity in stunning detail, providing groundbreaking insights into how spatial molecular organization shapes health and disease
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Tissue architecture is a product of a multilayered molecular landscape, where even subtle disruptions in the spatial context can initiate or reflect disease processes
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Spatial architecture of development and disease https://t.co/zH4ioL7vcR
#Review by Enikő Lázár & Joakim Lundeberg Free to read here:
nature.com
Nature Reviews Genetics - Spatial omics has empowered the discovery of developmental and disease-associated molecular signatures, cell states and multicellular niches, as well as the evaluation of...
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