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Siân Owen Profile
Siân Owen

@implosian

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Microbiologist & phage phanatic! Enthusiastic explorer of microbial genomes. New PI at the Wadsworth Center. Currently obsessed with plasmid-dependent phages

Boston, MA
Joined October 2009
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@implosian
Siân Owen
1 year
My lab is up and running and just needs enthusiastic phage biologists to populate it! Contact me or apply in the link if you are interested in a postdoc exploring plasmid-dependent phage biology in beautiful (and super affordable!) upstate New York🍎 https://t.co/nYWsBgNih4 1/3
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@implosian
Siân Owen
11 months
In case you needed a reason to go do a PhD with @APHage_ (other than the awesome science!)
@APHage_
Alexander Hynes
11 months
Dr. @rabiafatima_ has "tPASsed". Too many feels. Thank you @implosian - sorry you couldn't make it for the presentation of the warhammer. I do get asked if I fear the graduates will use them against me... no! Not in public, anyway - they're all far too smart to get caught.
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@EllieRand3
Ellie Rand
1 year
Get ready to dance, our paper – Phage DisCo: targeted discovery of bacteriophages by co-culture – has been pre-printed! 🪩 This has been a really fun project to work on with @implosian, @baym, @nquinoneso, Kesther and Carmen! https://t.co/k04NdEUvss 1/
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biorxiv.org
Phages interact with many components of bacterial physiology from the surface to the cytoplasm. Although there are methods to determine the receptors and intracellular systems a specified phage...
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@JeremyJBarr
Jeremy J Barr
1 year
Nature News piece on the hidden players of the gut microbiome (hint, they're phages, of course) “Our virome is hugely abundant and incredibly diverse, and we’ve looked at just a tiny percentage,” https://t.co/34DeKqF2DZ
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nature.com
Nature - Viruses known as bacteriophages are difficult to study, but they are beginning to give up their secrets.
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@NIHFunding
NIH Funding
1 year
Centers for Accelerating Phage (Bacteriophage) Therapy to Combat ESKAPE Pathogens (CAPT-CEP) (P01 Clinical Trial Not Allowed)
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@PRSecor
Patrick R. Secor
1 year
🚨We're hiring a lab manager/research scientist! Come work with us @MSU_MicroImmuno at Montana State in beautiful Bozeman, MT We are a phage lab with diverse projects related to infectious disease, check us out here: https://t.co/kvoFsCZRh5 apply here: https://t.co/b6iqyTDRZd
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@implosian
Siân Owen
1 year
Addendum: check out the glorious sunsets we get from our many-windowed lab space feat. views of the Catskill mountains in the day time
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@implosian
Siân Owen
1 year
We also have openings for technical staff and students! Contact me for more info, or if you are a undergraduate, consider applying to the UAlbany BMS program https://t.co/Ck9CPhWWbf 3/3
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@implosian
Siân Owen
1 year
Do you enjoy isolating phages? Do you like the idea of discovering and dissecting brand new & exotic organisms that could one day fight AMR? Just imagine what bounty awaits you in weekly wastewater deliveries from >200 treatment plants across NY! 🤤 https://t.co/fOMVDSd6ZE 2/3
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@MaucourtFlavien
Flavien Maucourt
1 year
https://t.co/iFQW5CgV7X @vivek_mutalik and @simroux_virus, this is your new graphical abstract:
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@implosian
Siân Owen
1 year
Another step forward towards the post-plaque era! Great work helping to drag the phage field into the 21st Century. Many core methodologies we use to study phages haven't changed since they were invented almost 100 years ago
@AntaniJo
Jyot Antani
1 year
Finally, the preprint on my postdoc work from the past 3 years! With mentorship from @PaulTurnerLab and @EmonetLab, I developed a microscopic technique to measure attachment of viruses #phages to bacterial cells @YalePhage @QbioYale . https://t.co/htw12nWx6V
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@implosian
Siân Owen
1 year
A great summary here of the challenges (and promises!) of studying non-canonical bacteriophages
@vivek_mutalik
Vivek Mutalik
1 year
Some partnerships are always fun!! Excited to share one such 🎉 product w @simroux_virus perspectives on our favorite “atypical” phages, for special issue to celebrate my former mentor Carol Gross @UCSF Tapping the treasure trove of atypical phages
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@vivek_mutalik
Vivek Mutalik
1 year
Some partnerships are always fun!! Excited to share one such 🎉 product w @simroux_virus perspectives on our favorite “atypical” phages, for special issue to celebrate my former mentor Carol Gross @UCSF Tapping the treasure trove of atypical phages
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@wheezenfeld
Type VI Sophia System
1 year
Come see Amy at poster 174 & learn about how active prophages may change the trajectory & evolution of resistance to DNA damaging antibiotics 💊 ⚡️ #EMBOEvoEco
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@BursteinLab
Burstein lab
1 year
Fellow microbial immunity, mobile elements, and plasmid enthusiasts: the paper of our wonderful @BruriaSamuel on anti-defense genes in plasmids is now published in @Nature!!! Check out her thread below for highlights of our new results. 1/2
@BruriaSamuel
Bruria Samuel
1 year
Meet The Shielded Plasmid🛡️🧬 Our new @Nature paper reveals how plasmids outsmart bacterial defenses during conjugation. It's all about being in the right place at the right time! The positioning of anti-defense genes boosts transfer efficiency🧵(1/7) https://t.co/6n8brUx1PU
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@ThomasMBartlett
Thomas M Bartlett
1 year
The Bartlett Lab is open for business at the Wadsworth Center! We study pathogens with "unusual" shapes (balls & corkscrews) to find vulnerabilities in their growth plans, and learn how bacterial shape impacts infection. We are hiring... join us! https://t.co/zNLe43FnAD
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@AsherLeeks
Asher Leeks
1 year
I'll be speaking about viral sociality at TEDxNewEngland on Wednesday 25th September, alongside a great lineup of other speakers. List of speakers & tickets here for anyone in the Boston area who might want to come: https://t.co/RRj0XtZ3yR #TEDxNE #SocialViruses #LoveVirology
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tedxnewengland.com
Bridging the gaps
@TEDxNE
Old TEDxNE Account
1 year
Asher Leeks is pushing the boundaries of biomedical science with his innovative research on sociality in viruses🦠. To hear more about @AsherLeeks' approach to the future of viral research, attend our inaugural MIND+LIFE conference on 9/25. Info in bio.
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@implosian
Siân Owen
1 year
A nice little highlight here in @NatureRevMicro by @cazares_adr and team on our work (+ from the Dechesne lab) rediscovering plasmid-dependent phages! A hundred or so are known (most isolated in the last few years!) and we've only scratched the surface 👀
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nature.com
Nature Reviews Microbiology - This Genome Watch highlights how the revived interest in phages that target plasmid-carrying bacteria is expanding our knowledge of viral diversity, ecology and...
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@seth_shipman
Seth Shipman
1 year
Multiplexed editing of phage genomes using retrons, now published at @NatureBiotech with lots of new bells and whistles. @ChloeFishman @katecrawdaddy @BhattaraiKline @Darshini_Poola @thekarenzhang @alex_gonzadel @matromont https://t.co/rkVtTEhVo1
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@implosian
Siân Owen
1 year
The most beautiful exploration of a single phage's infection cycle that I have ever seen, incredible work @PlevkaLab !!
@PlevkaLab
Plevka Lab
1 year
📢 Publication alert 📢 Congratulations to Lucie Valentová on her debut paper! 👏 *Structure and replication of 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 phage JDB30* recently published in The EMBO Journal! https://t.co/VI7Ln68LEV #PhageResearch @CEITEC_Brno 🧵1/12
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