Tzu-Chiao Lu
@TzuChiaoLu
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Joined January 2016
This acquisition will bring together two pioneering companies with a shared vision: to make single cell analysis more powerful, affordable and accessible to researchers worldwide. Learn more: https://t.co/rtqbg7lFOa
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#AlzheimersDisease Affects Tissues Beyond the #Brain. @HongjieLi5 Belen lab @YeJin_YeahGene @TzuChiaoLu explain their findings in @TheScientistLLC. @NeuroCellPress @bcmhouston @bcmgenetics @BCMGradSchool @TCHResearchNews
https://t.co/Rqxa8ymgcJ
@TheScientistLLC
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Our new study, published on Neuron, shows how Alzheimer’s disease impact the whole body at the single cell level. Led by @YeJin_YeahGene and @TzuChiaoLu.
cell.com
Park and Lu et al. create a whole-organism Alzheimer’s disease (AD) Fly Cell Atlas to reveal how AD-associated proteins systemically affect the brain and body. Their work uncovers distinct effects of...
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Online now: Distinct systemic impacts of Aβ42 and Tau revealed by whole-organism snRNA-seq https://t.co/I4ddVM9emc
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#Alzheimers disease not only affects the #brain. @HongjieLi5 Belen lab @YeJin_YeahGene @TzuChiaoLu et al show it also impacts the whole body. @NeuroCellPress @bcmhouston @bcmgenetics @BCMGradSchool @TCHResearchNews
https://t.co/M9tmOnak2f
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Our December issue, featuring a Focus on Single Cell Genomics, is now live! https://t.co/SdhbkB1aLQ
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Big news! The fly connectome is featured on the cover of a special edition of Nature. This is all possible thanks to the collaboration of 292 members of The FlyWire Consortium! https://t.co/Mrz7Yrx1eU Check out the thread for an overview of the 9 #flywire papers published today
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This week in Science, @ScienceAdvances, and @ScienceTM, the #PsychENCODE Consortium lay out findings based on examining human brains at the single-cell level. Learn more: https://t.co/O1NCcM6zV8
#DecodingTheBrain
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An article in @NatureAging presents 'The Muscle Aging Cell Atlas' with around 200,000 single-cell and single-nuclei transcriptomes from 17 human donors, uncovering mechanisms of aging in muscle stem cells, and demonstrates parallels in mouse muscle aging. https://t.co/45z6OaGamN
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In the latest issue! Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD
cell.com
Cell-type-specific transcriptional changes across the ALS-FTLD disease spectrum are studied through an integrated single-cell atlas of the human motor and prefrontal cortices, revealing molecular...
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AD-Fly Cell Atlas is out: Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer’s Disease fly models | bioRxiv
biorxiv.org
Peripheral tissues become disrupted in Alzheimer’s Disease (AD). However, a comprehensive understanding of how the expression of AD-associated toxic proteins, Aβ42 and Tau, in neurons impacts the...
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Out today: SCENIC+ is a comprehensive toolbox for inferring and analyzing enhancer-driven gene regulatory networks (eGRN) using single-cell multiomic data. @steinaerts @seppe_winter @Bravo_Potato
https://t.co/favZOlwb79
nature.com
Nature Methods - SCENIC+ is a comprehensive toolbox for inferring and analyzing enhancer-driven gene regulatory networks using single-cell multiomic data.
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RIBOmap for spatially resolved single-cell translatomics is published today! Congrats to the whole team and thanks so much for the constructive feedback and great suggestion from the editor, reviewers, colleagues, and friends! https://t.co/Dmxbe7atn5
science.org
RIBOmap enables single-cell in situ profiling of mRNA translation in 3D for thousands of genes in intact cells and tissues.
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In Science, researchers present the Aging Fly Cell Atlas, a single-nucleus transcriptome map of the fruit fly as it ages. Learn more: https://t.co/RvYd8Wphxj
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Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution https://t.co/hzMtUyPWd0
science.org
The Aging Fly Cell Atlas reveals the transcriptional changes across tissues over the lifetime of a hallmark model organism, Drosophila melanogaster.
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Excited to announce the release of my Science paper today! Huge thanks to @HongjieLi5 , @mariabrbic , the dedicated members of Hongjie's lab, and all our incredible collaborators for their invaluable support.
Our Aging Fly Cell Atlas is out. Do different cell types age at the same rate? No. Which cell types age faster? Fat, liver and muscle. Which cell types age slower? Neurons. Great collaboration with @StephenQuake @HenriJasper @mariabrbic @TzuChiaoLu
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Happy to share our Aging Fly Cell Atlas - It's my first time working with so many people. Thanks to the AFCA team for accomplishing this work. @HongjieLi5 @mariabrbic @BCMFromtheLabs
Glad to share our Aging Fly Cell Atlas - our very first manuscript at Baylor @bcmgenetics @BCMFromtheLabs. @TzuChiaoLu @mariabrbic @drAOPisco @jure @lucksmith @StephenQuake
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